Abstract
Norman Barrett originally described two special conditions, namely, a congenital short esophagus with an intrathoracic gastric columnar lining and congenital gastric heterotropia in the esophagus with ulceration. Thereafter, these conditions began to be known as “Barrett's esophagus.” It is an acquired condition of esophageal columnar metaplasia following chronic gastroesophageal reflux, and the classical Barrett's esophagus has been defined as having a circumferential columnar metaplasia spreading minimally 3 cm or more upward from the esophagogastric junction, because the esophagogastric junction still tends to be difficult to recognize precisely. Recently, from the point of view of adenocarcinogenesis of the esophagus, the term and concept of short-segment Barrett's esophagus (SSBE) as a developing condition of the classical Barrett's esophagus and the confirmation of intestinal metaplasia has been required; however, the definition of Barrett's esophagus still remains controversial. In Japan, although the prevalence of short-segment Barrett's esophagus has been reported to vary considerably, from 1% to 52%, the prevalence of long-segment Barrett's esophagus (LSBE) tends to range from 0% to 2%, which is a quite lower rate than that observed in Western countries. The great difference in the prevalence of SSBE is caused by the differences in the criteria of the esophagogastric junction and the definition concerning the necessity of intestinal metaplasia. A universally accepted definition of Barrett's esophagus is thus needed to accurately determine its actual prevalence.
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N Vakil SV Zanten P Kahrilas J Dent R Jones InstitutionalAuthorNameGlobal Consensus Group (2006) ArticleTitleThe Montreal definition and classification of gastroesophageal reflux diseaseas: A global evidence-based consensus Am J Gastroenterol 101 1900–20 Occurrence Handle16928254 Occurrence Handle10.1111/j.1572-0241.2006.00630.x
A Watson RE Sampliner HD Appleman SJ Spechler NA Shepherd (2003) The definition of “Barrett's esophagus.” R Giuli JR Siewert D Countrier C Scarpignato (Eds) Barrett's esophagus John Libbey Eurotext Montrouge 1–4
WJ Blot S Devesa R Kneller JF Fraumeni SuffixJr (1991) ArticleTitleRising incidence of adenocarcinoma of the esophagus and gastric cardia JAMA 265 1287–9 Occurrence Handle1995976 Occurrence Handle10.1001/jama.265.10.1287 Occurrence Handle1:STN:280:DyaK3M7ktVOqsQ%3D%3D
SS Devesa WJ Blot JF Fraumeni (1988) ArticleTitleChanging patterns in the incidence of esophageal and gastric carcinoma in the United States Cancer (Phila) 83 2049–53 Occurrence Handle10.1002/(SICI)1097-0142(19981115)83:10<2049::AID-CNCR1>3.0.CO;2-2
J Powell CC McConkey (1990) ArticleTitleIncreasing incidence of adenocarcinoma of the gastric cardia and adjacent sites Br J Cancer 62 440–3 Occurrence Handle2206952 Occurrence Handle1:STN:280:DyaK3M%2Fgt1amsg%3D%3D
AA Botterweck LJ Schouten A Volovics E Dorant PA van Den Brandt (2000) ArticleTitleTrends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries Int J Epidemiol 29 645–54 Occurrence Handle10922340 Occurrence Handle10.1093/ije/29.4.645 Occurrence Handle1:STN:280:DC%2BD3cvlvVarug%3D%3D
M Endo (1990) ArticleTitleBarrett's esophagus: review of literatures Stomach Intest 25 391–7
H Makuuchi (1997) ArticleTitleDiagnosis and treatment of Barrett's esophagus Endosc Dig 9 879–89
M Nakamura T Kawano M Endo K Nagai K Yano Y Ohkura (1997) ArticleTitleSuperficial esophageal cancer in Barrett's esophagus: report of a case Stomach Intest 32 115–20 Occurrence Handle1:CAS:528:DyaK2sXmtFKnsQ%3D%3D
T Nishi H Makuuchi H Shimada O Chino Y Tanaka G Ohshiba S Himeno T Machimura T Sasaki T Tajima A Shigeta K Hibi (1997) ArticleTitleIncidence of Barrett's esophagus and Barrett's epithelium in endoscopic screening Endosc Dig 9 891–6
SJ Spechler (1997) ArticleTitleThe columnar-lined esophagus. History, terminology, and clinical issue Gastroenterol Clin N Am 26 455–66 Occurrence Handle10.1016/S0889-8553(05)70306-X Occurrence Handle1:STN:280:DyaK2svlsFSjsw%3D%3D
H Makuuchi (1996) ArticleTitleEndoscopic mucosal resection for early esophageal cancer: indication and techniques Dig Endosc 8 175–9
T Kawano M Endo (1988) Technique of endoscopic cardiac mucosectomy using a multipurpose tube H Bismuth JP Galmiche Huguier D Jaeck (Eds) Monduzzi Editore International Gastrosurgical Club Rome 171–5
T Kawano K Nagai H Inoue K Yano T Nagahama Y Izumi et al. (1997) ArticleTitleBiopsy diagnosis of Barrett's esophagus Endosc Dig 9 903–10
A Paull JS Ther MD Dalton RC Camp P Loeb RP Goyal (1976) ArticleTitleThe histological spectrum of Barrett's oesophagus N Engl J Med 295 476–80 Occurrence Handle940579 Occurrence Handle1:STN:280:DyaE283kt1yjtQ%3D%3D Occurrence Handle10.1056/NEJM197608262950904
T Nishimaki AH Holscher M Schuler E Bollschweiler K Becker JR Siewert (1991) ArticleTitleHistopathologic characteristics of early adenocarcinoma in Barrett's esophagus Cancer (Phila) 68 1731–6 Occurrence Handle10.1002/1097-0142(19911015)68:8<1731::AID-CNCR2820680814>3.0.CO;2-0 Occurrence Handle1:STN:280:DyaK38%2FgsFamug%3D%3D
P Sharma TG Morales RE Sampliner (1998) ArticleTitleShort-segment Barrett's esophagus: the need for standardization of the definition and of endoscopic criteria Am J Gastroenterol 93 1033–6 Occurrence Handle9672325 Occurrence Handle1:STN:280:DyaK1czjs1Sluw%3D%3D
NR Barrett (1950) ArticleTitleChronic peptic ulcer of the oesophagus and “oesophagitis.” Br J Surg 38 175–82 Occurrence Handle14791960 Occurrence Handle1:STN:280:DyaG3M%2FitFGisg%3D%3D
PR Allison AS Johnstone (1953) ArticleTitleThe oesophagus lined with gastric mucous membrane Thorax 8 87–101 Occurrence Handle13077502 Occurrence Handle1:STN:280:DyaG3s7gt1Gktw%3D%3D
R Moersch FH Ellis JR McDonald (1959) ArticleTitlePathologic changes occurring in severe reflux esophagitis Surg Gynecol Obstet 108 476–84 Occurrence Handle13635268 Occurrence Handle1:STN:280:DyaG1M%2FmsVyluw%3D%3D
J Hayward (1961) ArticleTitleThe lower end of the oesophagus Thorax 16 36–41 Occurrence Handle13712529 Occurrence Handle1:STN:280:DyaF3c%2Fjt1Sktg%3D%3D Occurrence Handle10.1136/thx.16.1.36
CG Bremner VP Lynch FH Ellis (1970) ArticleTitleBarrett's esophagus: congenital or acquired? An experimental study of esophageal mucosal regeneration in the dog Surgery (St. Louis) 68 209–16 Occurrence Handle1:STN:280:DyaK1Mvht12luw%3D%3D
Y Kawaura Y Tatsuzawa T Wakabayashi N Ikeda M Matsuda S Nishihara (2001) ArticleTitleImmunohistochemical study of p53, c-erbB-2, and PCNA in Barrett's esophagus with dysplasia and adenocarcinoma arising from experimental acid or alkaline reflux model J Gastroenterol 36 595–600 Occurrence Handle11578062 Occurrence Handle10.1007/s005350170042 Occurrence Handle1:STN:280:DC%2BD3MrjtFKqtA%3D%3D
DB Skinner BC Walther RH Riddell H Schmidt C Iascone TR DeMeester (1983) ArticleTitleBarrett's esophagus: comparison of benign and malignant cases Ann Surg 198 554–565 Occurrence Handle6625723 Occurrence Handle10.1097/00000658-198310000-00016 Occurrence Handle1:STN:280:DyaL2c%2Fit1Oktg%3D%3D
BJ Reid RC Haggitt LE Rubin PS Rabinovitch (1987) ArticleTitleBarrett's esophagus: correlation between flow cytometry and histology in detection of patients at risk for adenocarcinoma Gastroenterology 93 1–11 Occurrence Handle3582897 Occurrence Handle1:STN:280:DyaL2s3hvFOjug%3D%3D
SJ Spechler RK Goyal (1996) ArticleTitleThe columnar-lined esophagus, intestinal metaplasia and Norman Barrett Gastroenterology 110 614–21 Occurrence Handle8566611 Occurrence Handle10.1053/gast.1996.v110.agast960614 Occurrence Handle1:STN:280:DyaK287ls1SltA%3D%3D
TG Schnell SJ Sontag G Chejfec (l992) ArticleTitleAdenocarcinoma arising in tongues or short segments of Barrett's esophagus Dig Dis Sci 37 137–43 Occurrence Handle10.1007/BF01308357
GW Clark AP Ireland JH Peters P Chandrasoma TR DeMeester CG Bremner (1997) ArticleTitleShort-segment Barrett's esophagus: a prevalent complication of gastroesophageal reflux disease with malignant potential J Gastrointest Surg 1 113–22 Occurrence Handle9834337 Occurrence Handle10.1016/S1091-255X(97)80098-4 Occurrence Handle1:STN:280:DC%2BD28nhslSnsg%3D%3D
SJ Spechler JM Zeroogian DA Antonioli HH Wang RK Goyal (1994) ArticleTitlePrevalence of metaplasia at the gastro-oesophageal junction Lancet 344 1533–6 Occurrence Handle7983953 Occurrence Handle10.1016/S0140-6736(94)90349-2 Occurrence Handle1:STN:280:DyaK2M%2FnsFWguw%3D%3D
NJ Trudgill SK Suvama KC Kapur SA Riley (1997) ArticleTitleIntestinal metaplasia at the squamocolumnar junction in patients attending for diagnostic gastroscopy Gut 41 585–9 Occurrence Handle9414961 Occurrence Handle1:STN:280:DyaK1c%2Fns1KlsA%3D%3D Occurrence Handle10.1136/gut.41.5.585
S Nandurkar NJ Talley CJ Martin THK Ng S Adams (1997) ArticleTitleShort segment Barrett's oesophagus: prevalence, diagnosis and associations Gut 40 710–5 Occurrence Handle9245922 Occurrence Handle1:STN:280:DyaK2szovVKruw%3D%3D
AP Weston P Krumpotich WF Makdisi R Cherian A Dixon DH McGregor (1996) ArticleTitleShort segment Barrett's esophagus; clinical and histological features associated endoscopic findings, and association with gastric intestinal metaplasia Am J Gastroenterol 91 IssueID5 981–6 Occurrence Handle8633592 Occurrence Handle1:STN:280:DyaK283ht1OgsQ%3D%3D
SJ Spechler (1997) ArticleTitleShort and ultrashort Barrett's esophagus – what does it mean? Semin Gastrointest Dis 8 59–67 Occurrence Handle9109693 Occurrence Handle1:STN:280:DyaK2s3mtlyhsw%3D%3D
RE Sampliner (1988) ArticleTitlePractice guidelines on the diagnosis, surveillance and therapy of Barrett's esophagus Am J Gastroenterol 93 1028–31 Occurrence Handle10.1111/j.1572-0241.1998.00362.x
AJ Cameron AR Zinsmeister DJ Ballard JA Camey (1990) ArticleTitlePrevalence of columnar-lined Barrett's esophagus. Comparison of population-based clinical and autopsy findings Gastroenterology 99 918–22 Occurrence Handle2394347 Occurrence Handle1:STN:280:DyaK3czmsl2gsA%3D%3D
SJ Spechler JM Zeroogian DA Antonioli HH Wang RK Goyal (1994) ArticleTitlePrevalence of metaplasia at the gastro-oesophageal junction Lancet 344 1533–6 Occurrence Handle7983953 Occurrence Handle10.1016/S0140-6736(94)90349-2 Occurrence Handle1:STN:280:DyaK2M%2FnsFWguw%3D%3D
MH Johnston AS Hammond W Laskin DM Jones (1996) ArticleTitleThe prevalence and clinical characteristics of short segments of specialized intestinal metaplasia in the distal esophagus on routine endoscopy Am J Gastroenterol 91 1507–11 Occurrence Handle8759651 Occurrence Handle1:STN:280:DyaK28zit1Wlsw%3D%3D
AP Weston P Krmpotich WF Makdisi et al. (1996) ArticleTitleShort segment Barrett's esophagus: clinical and histological features, associated endoscopic findings, and association with gastric intestinal metaplasia Am J Gastroenterol 91 981–6 Occurrence Handle8633592 Occurrence Handle1:STN:280:DyaK283ht1OgsQ%3D%3D
TG Morales RE Sampliner A Bhattacharyya (l997) ArticleTitleIntestinal metaplasia of the gastric cardia Am J Gastroenterol 92 414–8
N Chalasani JM Wo JG Hunter et al. (1997) ArticleTitleSignificance of intestinal metaplasia in different areas of esophagus including esophagogastric junction Dig Dis Sci 42 603–7 Occurrence Handle9073146 Occurrence Handle10.1023/A:1018863529777 Occurrence Handle1:STN:280:DyaK2s3isFyktA%3D%3D
WK Hirota TM Loughney DJ Lazas et al. (1999) ArticleTitleSpecialized intestinal metaplasia, dysplasia and cancer of the esophagus and esophagogastric junction: prevalence and clinical data Gastroenterology 116 277–85 Occurrence Handle9922307 Occurrence Handle10.1016/S0016-5085(99)70123-X Occurrence Handle1:STN:280:DyaK1M7it12msg%3D%3D
CR de Mas M Kramer E Seifert G Rippin M Vieth M Stolte (1999) ArticleTitleShort Barrett: prevalence and risk factors Scand J Gastroenterol 34 1065–70 Occurrence Handle10582754 Occurrence Handle10.1080/003655299750024832 Occurrence Handle1:STN:280:DC%2BD3c%2FkslGkuw%3D%3D
LB Gerson K Shetler G Triadafilopoulos (2002) ArticleTitlePrevalence of Barrett's esophagus in asymptomatic individuals Gastroenterology 123 461–7 Occurrence Handle12145799 Occurrence Handle10.1053/gast.2002.34748
LC Caum SL Bizinelli JC Pisani HM Amarantes SO Ioshii ER Carmes (2003) ArticleTitleSpecialized intestinal metaplasia of the distal esophagus in gastroesophageal reflux disease: prevalence and clinico-demographic features Arq Gastroenterol 40 IssueID4 220–6 Occurrence Handle15264043 Occurrence Handle10.1590/S0004-28032003000400005
DK Rex OW Cummings M Shaw MD Cumings RK Wong RS Vasudeva (2003) ArticleTitleScreening for Barrett's esophagus in colonoscopy patients with and without heartburn Gastroenterology 125 1670–7 Occurrence Handle14724819 Occurrence Handle10.1053/j.gastro.2003.09.030
A Csendes G Smok P Burdiles O Korn M Gradiz J Rojas M Recio (2003) ArticleTitlePrevalence of intestinal metaplasia according to the length of the specialized columnar epithelium lining the distal esophagus in patients with gastroesophageal reflux Dis Esophagus 16 24–8 Occurrence Handle12581250 Occurrence Handle10.1046/j.1442-2050.2003.00284.x Occurrence Handle1:STN:280:DC%2BD3s%2FntFensA%3D%3D
J Ronkainen P Aro T Storskrubb SE Johansson T Lind E Bolling-Sternevald (2005) ArticleTitlePrevalence of Barrett's esophagus in the general population: an endoscopic study Gastroenterology 129 1825–31 Occurrence Handle16344051 Occurrence Handle10.1053/j.gastro.2005.08.053
JY Kim YS Kim MK Jung JJ Park DH Kang JS Kim (2005) ArticleTitlePrevalence of Barrett's esophagus in Korea Gastroenterol Hepatol 20 IssueID4 633–6 Occurrence Handle10.1111/j.1440-1746.2005.03749.x
B Westhoff S Brotze A Weston C McElhinney R Cherian MS Mayo (2005) ArticleTitleThe frequency of Barrett's esophagus in high-risk patients with chronic GERD Gastrointest Endosc 61 226–31 Occurrence Handle15729230 Occurrence Handle10.1016/S0016-5107(04)02589-1
BJ Kendall DC Whiteman (2006) ArticleTitleTemporal changes in the endoscopic frequency of new cases of Barrett's esophagus in an Australian health region Am J Gastroenterol 101 IssueID6 1178–82 Occurrence Handle16771933 Occurrence Handle10.1111/j.1572-0241.2006.00548.x
EM Ward HC Wolfsen SR Achem DS Loeb M Krishna LL Hemminger (2006) ArticleTitleBarrett's esophagus is common in older men and women undergoing screening colonoscopy regardless of reflux symptoms Am J Gastroenterol 101 12–7 Occurrence Handle16405528 Occurrence Handle10.1111/j.1572-0241.2006.00379.x
Sharma P, McCallum RW, Lundell L, et al. The geoprevalence of Barrett's esophagus. Presented at the Sixth OESO World Congress, Paris, France, September 2000
C Winters TC Spurling SJ Chobanian et al. (1987) ArticleTitleBarrett's esophagus: a prevalent occult complication of gastroesophageal reflux disease Gastroenterology 92 118–24 Occurrence Handle3781178
AJ Cameron (1997) ArticleTitleEpidemiology of columnar-lined esophagus and adenocarcinoma Gastroenterol Clin N Am 26 484–7 Occurrence Handle10.1016/S0889-8553(05)70308-3
AP Weston P Krmpotich WF Makdisi (1996) ArticleTitleShort segment Barrett's esophagus: clinical and histological features, associated endoscopic findings, and association with gastric intestinal metaplasia Am J Gastroenterol 91 981–6 Occurrence Handle8633592 Occurrence Handle1:STN:280:DyaK283ht1OgsQ%3D%3D
N Chalasani JM Wo JG Hunter JP Waring (1997) ArticleTitleSignificance of intestinal metaplasia in different areas of esophagus including esophagogastric junction Dig Dis Sci 42 603–7 Occurrence Handle9073146 Occurrence Handle10.1023/A:1018863529777 Occurrence Handle1:STN:280:DyaK2s3isFyktA%3D%3D
S Nandurkar NJ Tally CJ Martin et al. (1997) ArticleTitleShort segment Barrett's oesophagus: prevalence, diagnosis and associations Gut 40 710–5 Occurrence Handle9245922 Occurrence Handle1:STN:280:DyaK2szovVKruw%3D%3D Occurrence Handle10.1136/gut.40.6.710
RJ Mason CG Bremner (1998) ArticleTitleThe columnar-lined (Barrett's) oesophagus in black patients S Afr J Surg 36 61–2 Occurrence Handle9711134 Occurrence Handle1:STN:280:DyaK1czns12qsQ%3D%3D
AJ Prach TA MacDonald DA Hopwood DA Johnston (1997) ArticleTitleIncreasing incidence of Barrett's oesophagus: education, enthusiasm or epidemiology? Lancet 350 933 Occurrence Handle9314878 Occurrence Handle10.1016/S0140-6736(05)63269-2 Occurrence Handle1:STN:280:DyaK2svmtVCqtA%3D%3D
A Watson PI Reed CPJ Caygill et al. (1999) ArticleTitleChanging incidence of columnar-lined (Barrett's) oesophagus (CLO) in the UK Gastroenterology 116 A351
MO Gadour EA Ayoola (1999) ArticleTitleBarrett's oesophagus and oesophageal cancer in Saudi Arabia Gastroenterology 20 111–5 Occurrence Handle1:STN:280:DC%2BD3c7lvFOguw%3D%3D
P Sharma RE Sampliner (1998) ArticleTitleIncreasing incidence of adenocarcinoma of the esophagus (EA) and esophagogastric junction (EGJAJ): is short-segment Barrett's esophagus (SSBE) responsible? Am J Gastroenterol 93 1624
KY Ho JY Kang A Seow (1998) ArticleTitlePrevalence of gastrointestinal symptoms in a multiracial Asian population, with particular reference to reflux-type symptoms Am J Gastroenterol 93 1816–22 Occurrence Handle9772037 Occurrence Handle10.1111/j.1572-0241.1998.00526.x Occurrence Handle1:STN:280:DyaK1cvktlSgtw%3D%3D
Y Kumagai K Suyama M Mukai H Makuuchi M Ogami H Miyoshi et al. (1985) ArticleTitleIncidence of Barrett's epithelium and its association with reflux esophagitis Prog Dig Endosc 27 80–3
Y Hoshihara T Kogure (1997) ArticleTitleEndoscopic diagnosis of Barrett's epitheliumu Endosc Dig 9 897–901
Y Hoshihara T Yamamoto M Hashimoto N Yamamoto T Tanaka K Sugawara (1999) ArticleTitleEndoscopic diagnosis of Barrett's adenocarcinoma J Jpn Surg Soc 100 244–8
M Ohta T Kikuchi Y Shigematsu T Suzuki A Nakamura F Okamoto et al. (2001) ArticleTitleA study on endoscopic findings of reflux esophagitis and Barrett's esophagus. Tama Symposium J Gastroenterol 15 10–3
M Hongo T Shoji (2003) ArticleTitleEpidemiology of reflux disease and CLE in East Asia J Gastroenterol 38 25–30 Occurrence Handle12698867 Occurrence Handle10.1007/s00535-003-1208-6
T Kawano T Kouzu S Ohra M Kusano (2005) ArticleTitleThe prevalence of Barrett's mucosal in the Japanese Gastroenterol Endosc 47 951–61
Y Hoshihara T Kogure S Fukuchi (1986) ArticleTitleEndoscopic observation of longitudinal vessels at the lower esophagus and its clinical significance Gastroenterol Endosc 28 941–6
M Nakamura T Kawano M Endo T Iwai (1999) ArticleTitleIntestinal metaplasia at the esophagogastric junction in Japanese patients without clinical Barrett's esophagus Am J Gastroenterol 94 3145–9 Occurrence Handle10566705 Occurrence Handle10.1111/j.1572-0241.1999.01506.x Occurrence Handle1:STN:280:DC%2BD3c%2FjtV2rsw%3D%3D
T Shoji M Hongo S Fukudo et al. (1999) ArticleTitleIncreasing incidence of Barrett's esophagus and Barrett's carcinoma in Japan Gastroenterology 116 A312
T Kawano K Nagai T Nishikiage K Kawada M Nakamura (2002) ArticleTitleBarrett's mucosa, Barrett's adenocarcinoma and gastric cardiac carcinoma Endosc Dig 14 1131–6
T Kawano K Ogiya M Nakamura (2005) ArticleTitleProgression and extending speed of Barrett's esophagus Nipponn Rinsho 63 1350–5
AP Weston P Krmpotich WF Makdisi et al. (1996) ArticleTitleShort segment Barrett's esophagus: clinical and histological features, associated endoscopic findings, and association with gastric intestinal metaplasia Am J Gastroenterol 91 981–6 Occurrence Handle8633592 Occurrence Handle1:STN:280:DyaK283ht1OgsQ%3D%3D
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Kawano, T., Ogiya, K., Nakajima, Y. et al. Prevalence of Barrett's esophagus in Japan. Esophagus 3, 155–164 (2006). https://doi.org/10.1007/s10388-006-0095-3
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DOI: https://doi.org/10.1007/s10388-006-0095-3