Zusammenfassung
Die Peritonealdialyse (PD) hat sich als Nierenersatztherapie neben der Hämodialyse (HD) etabliert. Obwohl die PD eine der HD gleichwertige Form der Dialyse darstellt, bleibt die Zahl der Dialysepatienten an der PD weltweit niedrig und nimmt in manchen Ländern sogar ab. Die Gründe dafür sind unterschiedlich. Manchmal ist das betreuende medizinische Personal zu wenig mit der PD vertraut, kann Patienten nicht ausreichend über die verschiedenen Dialyseverfahren informieren und erwirbt daher zu wenig Erfahrung mit PD. Es bestehen einige Bedenken, die PD verschiedenen speziellen Gruppen von Patienten trotz ausgezeichneter Ergebnisse hinsichtlich Dialysequalität und langem Erhalt der Nierenrestfunktion, niedrigeren Kosten als an der HD und besserer Lebensqualität vieler PD-Patienten im Vergleich zu HD-Patienten vorzustellen. PD sollte jedoch bis auf wenige Ausnahmen allen Patienten mit terminaler Niereninsuffizienz als initiales Dialyseverfahren angeboten werden. Dies schließt Diabetiker, Patienten mit Nierentransplantatinsuffizienz, Patienten mit Herzinsuffizienz sowie ältere Patienten ein.
Summary
Peritoneal dialysis (PD) has become an established dialysis modality besides hemodialysis (HD). Although PD is an equal form of dialysis compared to HD, patients numbers on PD remain low worldwide. There are several reasons for this fact. The medical staff in some centers is not used to PD, so there is not enough information about the different dialysis methods available for the patients and the staff doesn’t get the training that would be necessary to get familiar with PD. There are some concerns about offering PD to certain groups of patients despite excellent results as to quality of dialysis, good preservation of residual renal function, low costs compared to HD and better quality of life than on HD. However, PD should be offered to all patients requiring dialysis with very few exeptions as an ideal initial dialysis method. This includes patients with diabetes, patients with kidney transplant failure, patients with congestive heart failure and older patients.
Literatur
Jain AK, Blake P, Cordy P, et al. Global trends in rates of peritoneal dialysis. J Am Soc Nephrol. 2012;23:533–44.
Goovaerts T, Jadoul M, Goffin E. Influence of a pre-dialysis education programme (PDEP) on the mode of renal replacement therapy. Nephrol Dial Transplant. 2005;20:1842–7.
Chanouzas D, Ng KP, Fallouh B, et al. What influences patient choice of treatment modality at the pre-dialysis stage? Nephrol Dial Transplant. 2012;27:1542–7.
Dalal P, Sangha H, Chaudhary K. In peritoneal dialysis, is there sufficient evidence to make “PD First” therapy? Int J Nephrol. 2011;2011:239515.
Moist LM, Bragg-Gresham JL, Pisoni RL, et al. Travel time to dialysis as a predictor of health-related quality of life, adherence, and mortality: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2008;51:641–50.
Núñez J, González M, Miñana G, et al. Continuous ambulatory peritoneal dialysis as a therapeutic alternative in patients with advanced congestive heart failure. Eur J Heart Fail. 2012;14:540–8.
Wu MS, Lin CL, Chang CT, et al. Improvement in clinical outcome by early nephrology referral in type II diabetics on maintenance peritoneal dialysis. Perit Dial Int. 2003;23:39–45.
Theofilou P. Quality of life in patients undergoing hemodialysis or peritoneal dialysis treatment. J Clin Med Res. 2011;3:132–8.
Brown EA, Johansson L, Farrington K, et al. Broadening Options for Long-term Dialysis in the Elderly (BOLDE): differences in quality of life on peritoneal dialysis compared to haemodialysis for older patients. Nephrol Dial Transplant. 2010;25:3755–63.
De Vecchi AF, Dratwa M, Wiedemann ME. Healthcare systems and end-stage renal disease (ESRD) therapies—an international review: costs and reimbursement/funding of ESRD therapies. Nephrol Dial Transplant. 1999;14 Suppl 6:31–41.
Sennfält K, Magnusson M, Carlsson P. Comparison of hemodialysis and peritoneal dialysis—a cost-utility analysis. Perit Dial Int. 2002;22:39–47.
Sanabria M, Muñoz J, Trillos C, et al. Dialysis outcomes in Colombia (DOC) study: a comparison of patient survival on peritoneal dialysis vs hemodialysis in Colombia. Kidney Int Suppl. 2008;108:S165–72.
Chiu YW, Jiwakanon S, Lukowsky L, et al. An update on the comparisons of mortality outcomes of hemodialysis and peritoneal dialysis patients. Semin Nephrol. 2011;31:152–8.
Weinhandl ED, Foley RN, Gilbertson DT, et al. Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients. J Am Soc Nephrol. 2010;21:499–506.
Termorshuizen F, Korevaar JC, Dekker FW, et al. Hemodialysis and peritoneal dialysis: comparison of adjusted mortality rates according to the duration of dialysis: analysis of The Netherlands Cooperative Study on the Adequacy of Dialysis 2. J Am Soc Nephrol. 2003;14:2851–60.
Liem YS, Wong JB, Hunink MG, et al. Comparison of hemodialysis and peritoneal dialysis survival in The Netherlands. Kidney Int. 2007;71:153–8.
Moist LM, Port FK, Orzol SM, et al. Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol. 2000;11:556–64.
Plum J, Schoenicke G, Kleophas W, et al. Comparison of body fluid distribution between chronic haemodialysis and peritoneal dialysis patients as assessed by biophysical and biochemical methods. Nephrol Dial Transplant. 2001;16:2378–85.
Menon MK, Naimark DM, Bargman JM, et al. Long-term blood pressure control in a cohort of peritoneal dialysis patients and its association with residual renal function. Nephrol Dial Transplant. 2001;16:2207–13.
Ates K. Salt and water in PD: the Turkish contribution. Perit Dial Int. 2008;28:224–8.
Günal AI, Duman S, Ozkahya M, et al. Strict volume control normalizes hypertension in peritoneal dialysis patients. Am J Kidney Dis. 2001;37:588–93.
Medcalf JF, Harris KP, Walls J. Role of diuretics in the preservation of residual renal function in patients on continuous ambulatory peritoneal dialysis. Kidney Int. 2001;59:1128–33.
Konings CJ, Kooman JP, Schonck M, et al. Fluid status in CAPD patients is related to peritoneal transport and residual renal function: evidence from a longitudinal study. Nephrol Dial Transplant. 2003;18:797–803.
Van Biesen W, Williams JD, Covic AC, et al. Fluid status in peritoneal dialysis patients: the European Body Composition Monitoring (EuroBCM) study cohort. PLoS One. 2011;6:e17148.
Aslam N, Bernardini J, Fried L, et al. Comparison of infectious complications between incident hemodialysis and peritoneal dialysis patients. Clin J Am Soc Nephrol. 2006;1:1226–33.
Ishani A, Collins AJ, Herzog CA, et al. Septicemia, access and cardiovascular disease in dialysis patients: the USRDS Wave 2 study. Kidney Int. 2005;68:311–8.
Hommel K, Madsen M, Kamper AL. The importance of early referral for the treatment of chronic kidney disease: a Danish nationwide cohort study. BMC Nephrol. 2012;13:108.
Hingwala J, Diamond J, Tangri N, et al. Underutilization of peritoneal dialysis: the role of the nephrologist’s referral pattern. Nephrol Dial Transplant. 2013;28(3):732–40.
Plantinga LC, Fink NE, Finkelstein FO, et al. Association of peritoneal dialysis clinic size with clinical outcomes. Perit Dial Int. 2009;29:285–91.
König P. Peritoneal dialysis indication–importance of psychosocial aspects of the indications of the situation. Wien Klin Wochenschr. 2005;117 Suppl 6:5–11.
Kessler M, Frimat L, Panescu V, et al. Impact of nephrology referral on early and midterm outcomes in ESRD: EPidémiologie de l’Insuffisance REnale chronique terminale en Lorraine (EPIREL): results of a 2-year, prospective, community-based study. Am J Kidney Dis. 2003;42:474–85.
Parameswaran S, Geda SB, Rathi M, et al. Referral pattern of patients with end-stage renal disease at a public sector hospital and its impact on outcome. Natl Med J India. 2011;24:208–13.
Song JH, Kim GA, Lee SW, Kim MJ, et al. Clinical outcomes of immediate full-volume exchange one year after peritoneal catheter implantation for CAPD. Perit Dial Int. 2000;20:194–9.
Yang YF, Wang HJ, Yeh CC, et al. Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters. Perit Dial Int. 2011;31:551–7.
Povlsen JV, Ivarsen P. How to start the late referred ESRD patient urgently on chronic APD. Nephrol Dial Transplant. 2006;21 Suppl 2:ii56–9.
Brown EA, Davies SJ, Rutherford P, et al. Survival of functionally anuric patients on automated peritoneal dialysis: the European APD Outcome Study. J Am Soc Nephrol. 2003;14:2948–57.
Mendelssohn DC, Mujais SK, Soroka SD, et al. A prospective evaluation of renal replacement therapy modality eligibility. Nephrol Dial Transplant. 2009;24:555–61.
Wuerth DB, Finkelstein SH, Schwetz O, et al. Patients’ descriptions of specific factors leading to modality selection of chronic peritoneal dialysis or hemodialysis. Perit Dial Int. 2002;22:184–90.
Pérez Fontán M, Rodríguez-Carmona A, López-Muñiz A, et al. Getting the right patient on the right renal replacement therapy. Contrib Nephrol. 2012;178:40–6.
Liebman SE, Bushinsky DA, Dolan JG, et al. Differences between dialysis modality selection and initiation. Am J Kidney Dis. 2012;59:550–7.
Boateng EA, East L. The impact of dialysis modality on quality of life: a systematic review. J Ren Care. 2011;37:190–200.
Ginieri-Coccossis M, Theofilou P, Synodinou C, et al. Quality of life, mental health and health beliefs in haemodialysis and peritoneal dialysis patients: investigating differences in early and later years of current treatment. BMC Nephrol. 2008;9:14.
Domenici A, Comunian MC, Fazzari L, et al. Incremental peritoneal dialysis favourably compares with hemodialysis as a bridge to renal transplantation. Int J Nephrol. 2011;2011:204216.
Foggensteiner L, Baylis J, Moss H, et al. Timely initiation of dialysis–single-exchange experience in 39 patients starting peritoneal dialysis. Perit Dial Int. 2002;22:471–6.
Michels WM, Verduijn M, Boeschoten EW, et al. Similar survival on automated peritoneal dialysis and continuous ambulatory peritoneal dialysis in a large prospective cohort. Clin J Am Soc Nephrol. 2009;4:943–9.
Blake PG. Integrated end-stage renal disease care: the role of peritoneal dialysis. Nephrol Dial Transplant. 2001;16 Suppl 5:61–6.
Verger C, Ryckelynck JP, Duman M, et al. French peritoneal dialysis registry (RDPLF): outline and main results. Kidney Int Suppl. 2006;103:S12–20.
Li PK, Szeto CC. Success of the peritoneal dialysis programme in Hong Kong. Nephrol Dial Transplant. 2008;23:1475–8.
Brown EA. How to address barriers to peritoneal dialysis in the elderly. Perit Dial Int. 2011;31 Suppl 2:S83–5.
Brown EA, Dratwa M, Povlsen JV. Assisted peritoneal dialysis—an evolving dialysis modality. Nephrol Dial Transplant. 2007;22:3091–2.
Dimkovic N, Oreopoulos DG. Assisted peritoneal dialysis as a method of choice for elderly with end-stage renal disease. Int Urol Nephrol. 2008;40:1143–50.
Maitra S, Jassal SV, Shea J, et al. Increased mortality of elderly female peritoneal dialysis patients with diabetes—a descriptive analysis. Adv Perit Dial. 2001;17:117–21.
Vonesh EF, Snyder JJ, Foley RN, et al. The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysis. Kidney Int. 2004;66:2389–401.
Locatelli F, Pozzoni P, Del Vecchio L. Renal replacement therapy in patients with diabetes and end-stage renal disease. J Am Soc Nephrol. 2004;15 Suppl 1:S25–9.
United States Renal Data System. Annual data report: Atlas of chronic kidney disease & end-stage renal disease in the United States, 2010.
Tang W, Cheng LT, Wang T. Diabetic patients can do as well on peritoneal dialysis as nondiabetic patients. Blood Purif. 2005;23:330–7.
Cotovio P, Rocha A, Rodrigues A. Peritoneal dialysis in diabetics: there is room for more. Int J Nephrol. 2011;2011:914849.
Paniagua R, Ventura MD, Avila-Díaz M, et al. Icodextrin improves metabolic and fluid management in high and high-average transport diabetic patients. Perit Dial Int. 2009;29:422–32.
Koch M, Haastert B, Kohnle M, et al. Peritoneal dialysis relieves clinical symptoms and is well tolerated in patients with refractory heart failure and chronic kidney disease. Eur J Heart Fail. 2012;14:530–9.
Sánchez JE, Ortega T, Rodríguez C, et al. Efficacy of peritoneal ultrafiltration in the treatment of refractory congestive heart failure. Nephrol Dial Transplant. 2010;25:605–10.
Movilli E, Viola BF, Brunori G, et al. Long-term effects of arteriovenous fistula closure on echocardiographic functional and structural findings in hemodialysis patients: a prospective study. Am J Kidney Dis. 2010;55:682–9.
Badve SV, Hawley CM, McDonald SP, et al. Effect of previously failed kidney transplantation on peritoneal dialysis outcomes in the Australian and New Zealand patient populations. Nephrol Dial Transplant. 2006;21:776–83.
Mujais S, Story K. Patient and technique survival on peritoneal dialysis in patients with failed renal allograft: a case-control study. Kidney Int Suppl. 2006;103:S133–7.
Duman S, AŠçi G, Töz H, et al. Patients with failed renal transplant may be suitable for peritoneal dialysis. Int Urol Nephrol. 2004;36:249–52.
Andreetta B, Verrina E, Sorino P, et al. Complications linked to chronic peritoneal dialysis in children after kidney transplantation: experience of the Italian Registry of Pediatric Chronic Peritoneal Dialysis. Perit Dial Int. 1996;16 Suppl 1:S570–3.
Vychytil A, Lorenz M, Schneider B, et al. New strategies to prevent Staphylococcus aureus infections in peritoneal dialysis patients. J Am Soc Nephrol. 1998;9:669–76.
De Jonge H, Bammens B, Lemahieu W, et al. Comparison of peritoneal dialysis and haemodialysis after renal transplant failure. Nephrol Dial Transplant. 2006;21:1669–74.
Sasal J, Naimark D, Klassen J, et al. Late renal transplant failure: an adverse prognostic factor at initiation of peritoneal dialysis. Perit Dial Int. 2001;21:405–10.
Perl J, Hasan O, Bargman JM, et al. Impact of dialysis modality on survival after kidney transplant failure. Clin J Am Soc Nephrol. 2011;6:582–90.
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Puttinger, H. Peritonealdialyse – ein ideales initiales Dialyseverfahren. Wien Med Wochenschr 163, 271–279 (2013). https://doi.org/10.1007/s10354-013-0200-x
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DOI: https://doi.org/10.1007/s10354-013-0200-x