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Quo vadis NOTES?

Quo vadis NOTES?

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Zusammenfassung

GRUNDLAGEN: Der Begriff NOTES® (Natural Orifice Translumenal Endoscopic Surgery) fasst neue Operationstechniken zusammen, die eine Synthese aus Endoskopie und Laparoskopie darstellen und keine sichtbaren Narben an der Körperoberfläche hinterlassen. METHODIK: Anhand der Literatur einerseits und eigenen Erfahrungen aus experimentellen und klinischen NOTES® Fällen andererseits, werden Geräte, Zugänge, Nahttechniken, Infektionsprophylaxe und Risiken angesprochen. ERGEBNISSE: NOTES® ist mittlerweile klinische Realität geworden. Über 300 Cholezystektomien an Patienten wurden bis Juli 2008 in mehreren Ländern unter Aufsicht der jeweiligen Ethikkomissionen durchgeführt. Die Operationsergebnisse entsprechen denen von traditioneller Laparoskopie, bei besserem kosmetischen Ergebnis. Es gibt Anzeichen, die auf geringeren postoperativen Schmerzmittelbedarf hindeuten, ob schnellere Rekonvaleszenz auch zu den Vorteilen von NOTES® gehört, bleibt abzuwarten. SCHLUSSFOLGERUNGEN: Flexible Laparoskopie und Thorakoskopie hat Zukunft. Abgesehen vom besseren kosmetischen Resultat, sind auch raschere Belastbarkeit der Bauchdecke postoperativ, sowie atraumatische Erreichbarkeit von Organen im Mediastinum ein Vorteil von NOTES® Instrumentarium. Ob mit diesen neuen Geräten dann ein translumenaler oder Single-Port-Zugang gewählt wird, können Patient und Arzt nach umfassender Aufklärung individuell entscheiden.

Summary

BACKGROUND: The term NOTES® (Natural Orifice Transluminal Endoscopic Surgery) summarizes new operation techniques, which are a synthesis of endoscopy and laparoscopy, and do not leave scars on patients' skin. METHODS: The article reviews the literature on the one hand and reflects our personal experience with experimental and clinical NOTES® cases on the other hand, discussing devices, approaches, tissue approximation techniques, prevention of infection, and risks. RESULTS: NOTES® has become a clinical reality. More than 300 human cases have been performed worldwide under IRB (Institutional Research Board) approval by July 2008. The results have been the same as if laparoscopy had been performed, with better cosmetic results. Some studies show a tendency towards lesser use of postoperative pain medication. It has to be proved if faster recovery is also an advantage of NOTES®. CONCLUSIONS: There is a future for flexible laparoscopy and thoracoscopy. NOTES® instruments provide better cosmetic results, leave the abdominal wall intact, and may have advantages for atraumatic surgery in the mediastinum. Patients and physicians can decide individually if the new available devices will be used in a transluminal or single port approach after intensive consideration of advantages and drawbacks of each access approach.

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References

  • Hirschowitz BI, Curtiss LE, Peters CW, Pollard HM. Demonstration of a new gastroscope, the fiberscope. Gastroenterology 1958;35(1):50; discussion 51–3

    PubMed  CAS  Google Scholar 

  • McCune WS, Shorb PE, Moscovitz H. Endoscopic cannulation of the ampulla of water: a preliminary report. Ann Surg 1968;167(5):752–6

    Article  PubMed  CAS  Google Scholar 

  • Classen M. Fibreendoscopy of the intestines. Gut 1971;12(4):330–8

    Article  PubMed  CAS  Google Scholar 

  • Swanstrom L. Transanal endoscopic microsurgery: current indications and techniques. J Gastrointest Surg 2000;4(4):342–3

    Article  PubMed  CAS  Google Scholar 

  • Swain P, Park PO, Mills T. Bard EndoCinch: the device, the technique, and pre-clinical studies. Gastrointest Endosc Clin N Am 2003;13(1):75–88

    Article  PubMed  Google Scholar 

  • Gavagan JA, Whiteford MH, Swanstrom LL. Full-thickness intraperitoneal excision by transanal endoscopic microsurgery does not increase short-term complications. Am J Surg 2004;187(5):630–4

    Article  PubMed  Google Scholar 

  • Kalloo AN, Singh VK, Jagannath SB, et al. Flexible transgastric peritoneoscopy: a novel approach to diagnostic and therapeutic interventions in the peritoneal cavity. Gastrointest Endosc 2004;60(1):114–7

    Article  PubMed  Google Scholar 

  • Jagannath SB, Kantsevoy SV, Vaughn CA, et al. Peroral transgastric endoscopic ligation of fallopian tubes with long-term survival in a porcine model. Gastrointest Endosc 2005;61(3):449–53

    Article  PubMed  Google Scholar 

  • Park PO, Bergstrom M, Ikeda K, Fritscher-Ravens A, Swain P. Experimental studies of transgastric gallbladder surgery: cholecystectomy and cholecystogastric anastomosis (videos). Gastrointest Endosc 2005;61(4):601–6

    Article  PubMed  Google Scholar 

  • Kantsevoy SV, Jagannath SB, Niiyama H, et al. Endoscopic gastrojejunostomy with survival in a porcine model. Gastrointest Endosc 2005;62(2):287–92

    Article  PubMed  Google Scholar 

  • Kantsevoy SV, Hu B, Jagannath SB, et al. Transgastric endoscopic splenectomy: is it possible? Surg Endosc 2006;20(3):522–5

    Article  PubMed  CAS  Google Scholar 

  • ASGE/SAGES Working group on natural orifice translumenal endoscopic surgery white paper October 2005. Gastrointest Endosc 2006;63(2):199–203

    Google Scholar 

  • Zorron R, Filgueiras M, Maggioni LC, Pombo L, Lopes Carvalho G, Lacerda Oliveira A. NOTES.Transvaginal cholecystectomy: report of the first case. Surg Innov 2007;14(4):279–83

    Article  PubMed  Google Scholar 

  • Bessler M, Stevens PD, Milone L, Hogle NJ, Durak E, Fowler D. Transvaginal laparoscopic cholecystectomy: laparoscopically assisted. Surg Endosc 2008;6:6

    Google Scholar 

  • Marescaux J, Dallemagne B, Perretta S, Wattiez A, Mutter D, Coumaros D. Surgery without scars: report of transluminal cholecystectomy in a human being. Arch Surg 2007;142(9):823–6; discussion 826–7

    Article  PubMed  Google Scholar 

  • Swanstrom LL. IRB Requirements for Human NOTES Procedures. SAGES Philadelphia, PA, April, 10th, 2008

  • Dolz C, Noguera JF, Martin A, Vilella A, Cuadrado A. [Transvaginal cholecystectomy (NOTES) combined with minilaparoscopy]. Rev Esp Enferm Dig 2007;99(12):698–702

    Article  PubMed  CAS  Google Scholar 

  • Swanstrom LL, Hansen P: Laparoscopic total esophagectomy. Arch Surg 1997;132(9):943–947; discussion 947–9

    PubMed  CAS  Google Scholar 

  • Ludemann R, Swanstrom LL. Totally laparoscopic abdominal aortic aneurysm repair. Semin Laparosc Surg 1999;6(3):153–63

    PubMed  CAS  Google Scholar 

  • Swanstrom LL. Endoscopic surgery for pancreaticobiliary cancer. Surg Endosc 1998;12(4):370–1

    Article  PubMed  Google Scholar 

  • Swanstrom LL, Kozarek R, Pasricha PJ, et al. Development of a new access device for transgastric surgery. J Gastrointest Surg 2005;9(8):1129–1136; discussion 1136–7

    Article  PubMed  Google Scholar 

  • Bardaro SJ, Swanstrom L. Development of advanced endoscopes for Natural Orifice Transluminal Endoscopic Surgery (NOTES). Minim Invasive Ther Allied Technol 2006;15(6):378–83

    Article  PubMed  Google Scholar 

  • Swanstrom L, Zheng B. Spatial Orientation and Off-Axis Challenges for NOTES. Gastrointest Endosc Clin N Am 2008;18(2):315–24

    Article  PubMed  Google Scholar 

  • Scott DJ, Tang SJ, Fernandez R, et al. Completely transvaginal NOTES cholecystectomy using magnetically anchored instruments. Surg Endosc 2007;21(12):2308–16

    Article  PubMed  Google Scholar 

  • Fritscher-Ravens A, Patel K, Ghanbari A, et al. Natural orifice transluminal endoscopic surgery (NOTES) in the mediastinum: long-term survival animal experiments in transesophageal access, including minor surgical procedures. Endoscopy 2007;39(10):870–5

    Article  PubMed  CAS  Google Scholar 

  • Sumiyama K, Gostout CJ, Rajan E, et al. Pilot study of transesophageal endoscopic epicardial coagulation by submucosal endoscopy with the mucosal flap safety valve technique (with videos). Gastrointest Endosc 2008;67(3):497–501

    Article  PubMed  Google Scholar 

  • Zorron R. NOTES Transvaginal Cholecystectomy- Comperative Clinical Study with Laparoscopy. Digestive Disease Week 2008 San Diego, May, 20th 2008, 2008

  • Whiteford MH, Denk PM, Swanstrom LL. Feasibility of radical sigmoid colectomy performed as natural orifice translumenal endoscopic surgery (NOTES) using transanal endoscopic microsurgery. Surg Endosc 2007;21(10):1870–4

    Article  PubMed  CAS  Google Scholar 

  • Meining A, Wilhelm D, Burian M, et al. Development, standardization, and evaluation of NOTES cholecystectomy using a transsigmoid approach in the porcine model: an acute feasibility study. Endoscopy 2007;39(10):860–4

    Article  PubMed  CAS  Google Scholar 

  • Lima E, Henriques-Coelho T, Rolanda C, et al. Transvesical thoracoscopy: a natural orifice translumenal endoscopic approach for thoracic surgery. Surg Endosc 2007;21(6):854–8

    Article  PubMed  Google Scholar 

  • Seaman DL, Gostout CJ, de la Mora Levy JG, Knipschield MA. Tissue anchors for transmural gut-wall apposition. Gastrointest Endosc 2006;64(4):577–81

    Article  PubMed  Google Scholar 

  • Kantsevoy SV. Infection Prevention in NOTES. Gastrointest Endosc Clin N Am 2008;18(2):291–6

    Article  PubMed  Google Scholar 

  • Chopita N, Vaillaverde A, Cope C, et al. Endoscopic gastroenteric anastomosis using magnets. Endoscopy 2005;37(4):313–7

    Article  PubMed  CAS  Google Scholar 

  • Zornig C, Mofid H, Emmermann A, Alm M, von Waldenfels HA, Felixmuller C. Scarless cholecystectomy with combined transvaginal and transumbilical approach in a series of 20 patients. Surg Endosc 2008;9:9

    Google Scholar 

  • Cuesta MA, Berends F, Veenhof AA. The invisible cholecystectomy A transumbilical laparoscopic operation without a scar. Surg Endosc 2007;18:18

    Google Scholar 

  • Haber GP, Crouzet S, Kamoi K, et al. Robotic NOTES (Natural Orifice Translumenal Endoscopic Surgery) in Reconstructive Urology: Initial Laboratory Experience. Urology 2008;1:1

    Google Scholar 

  • Pasricha PJ, Hawari R, Ahmed I, et al. Submucosal endoscopic esophageal myotomy: a novel experimental approach for the treatment of achalasia. Endoscopy 2007;39(9):761–4

    Article  PubMed  CAS  Google Scholar 

Download references

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Correspondence to L. L. Swanström.

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Spaun, G., Swanström, L. Quo vadis NOTES?. Eur Surg 40, 211–219 (2008). https://doi.org/10.1007/s10353-008-0428-7

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  • DOI: https://doi.org/10.1007/s10353-008-0428-7

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