Skip to main content
Log in

Internal hydrocephalus combined with pachygyria in a wild-born brown bear cub

  • Short Communication
  • Published:
European Journal of Wildlife Research Aims and scope Submit manuscript

Abstract

An abandoned wild-born male brown bear (Ursus arctos) cub of the year was found and subsequently placed in a zoo. At 7 months of age, the cub showed first signs of ataxia, and at 13 months of age, it was unable to move the hind legs and exhibited outbursts of aggressive behavior and self-mutilation. The animal was euthanized, and necropsy revealed alterations of the brain with obviously flattened gyri, profound enlargement of both lateral ventricles and considerable accumulation of cerebrospinal fluid, disruption of the septum pellucidum, and atrophy of the hippocampus. The animal was diagnosed with an internal hydrocephalus and pachygyria. Genetic evidence showed that the father of the described cub was also the father of the cub’s mother, suggesting the possibility of congenital hydrocephalus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  • Abramo F, Poli A (1991) Unilateral hydrocephalus in a wild European brown hare (Lepus europaeus). J Wildl Dis 27:331–333

    PubMed  CAS  Google Scholar 

  • Axthelm MK, Leipold HW, Phillips RM (1981) Congenital internal hydrocephalus in polled Hereford cattle. Vet Med Small Anim Clin 76:567–570

    PubMed  CAS  Google Scholar 

  • Bellemain E, Zedrosser A, Manel S, Waits LP, Swenson JE, Taberlet P (2006) The dilemma of female mate selection in the brown bear, a species with sexually selected infanticide. Proc R Soc Lond B Biol Sci 273:283–291. doi:10.1098/rspb.2005.3331

    Article  Google Scholar 

  • Bruni JE, Del Bigio MR, Cardoso ER, Persaud TVN (1988) Hereditary hydrocephalus in laboratory animals and humans. Exp Pathol 35:239–246

    PubMed  CAS  Google Scholar 

  • Champoux M, Kriete MF, Eckhaus MA, Suomis SJ (1997) Behavioral and physical concomitants of congenital hydrocephalus in a rhesus macaque (Macaca mulatta) neonate. Contemp Top Lab Anim Sci 36:56–61

    PubMed  Google Scholar 

  • Grappendorf H (1995) Sudden central blindness in a 4-month-old puppy caused by congenital internal hydrocephalus. Prakt Tierarzt 76:301–302

    Google Scholar 

  • Greene CE, Vandefelde M, Braund K (1976) Lissencephaly in two Lhasa Apso dogs. J Am Vet Med Assoc 196:405–410

    Google Scholar 

  • Greene HJ, Saperstein G, Schalles R, Leipold HW (1978) Internal hydrocephalus and retinal dysplasia in shorthorn cattle. Ir Vet J 32:65–69

    Google Scholar 

  • Halstead JR, Kiel FW (1962) Hydrocephalus in a bear. J Am Vet Med Assoc 141:367–368

    Google Scholar 

  • Harding B, Copp AJ (2002) Malformations. In: Graham DI, Lantos PL (eds) Greenfield’s neuropathology, 7th edn. Arnold, London, pp 357–483

    Google Scholar 

  • Ironside JW, Pickard JD (2002) Raised intracranial pressure, oedema and hydrocephalus. In: Graham DI, Lantos PL (eds) Greenfield’s neuropathology, 7th edn. Arnold, London, pp 193–231

    Google Scholar 

  • Koestner A, Jones TC (1996) The nervous system. In: Jones TC, Hunt RD, King NW (eds) Veterinary pathology, 6th edn. Williams & Wilkins, Baltimore, pp 1259–1297

    Google Scholar 

  • Mandara MT, Pavone S, Vitellozzi G (2007) Internal hydrocephalus and associated periventricular encephalitis in a young fox. Vet Pathol 44:713–716. doi:10.1354/vp.44-5-713

    Article  PubMed  CAS  Google Scholar 

  • Pumarola M, Van Niel MHF (1992) Obstructive hydrocephalus produced by parasitic granulomas in a dog. J Am Vet Med Assoc 39:392–395

    CAS  Google Scholar 

  • Raymond J, Lin TL, Breitwieser B (1998) Clinical challenge—internal hydrocephalus. J Zoo Wildl Med 29:87–88

    PubMed  CAS  Google Scholar 

  • Sorjonen DC, Silberman MS, Knecht CD, Hoff EJ, Pechman RD (1982) Hydrocephalus, ependymitis, and encephalitis in an Asian black bear (Selenarctos tibetanus). J Zoo Anim Med 13:18–22

    Google Scholar 

  • Summers BA, Cummings JF, de Lahunta A (1995) Malformations of the central nervous system. In: Summers BA, Cummings JF, de Lahunta A (eds) Veterinary neuropathology. Mosby-Year Book Inc., St. Louis, pp 68–94

    Google Scholar 

  • Tait DEN (1980) Abandonment as reproductive tactic—the example of grizzly bears. Am Nat 115:800–808. doi:10.1086/283601

    Article  Google Scholar 

  • Zedrosser A, Rauer G, Kruckenhauser L (2004) Early primiparity in brown bears. Acta Theriol (Warsz) 49:427–432

    Google Scholar 

Download references

Acknowledgements

We would like to thank the Austrian Science Fund project P16236-B06 (funding for A. Zedrosser).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Anna Kübber-Heiss.

Additional information

Communicated by F.-J. Kaup

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kübber-Heiss, A., Zedrosser, A., Rauer, G. et al. Internal hydrocephalus combined with pachygyria in a wild-born brown bear cub. Eur J Wildl Res 55, 539–542 (2009). https://doi.org/10.1007/s10344-009-0282-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10344-009-0282-3

Keywords

Navigation