Skip to main content

Advertisement

SpringerLink
Log in

A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis

  • Research
  • Published:
Neurosurgical Review Aims and scope Submit manuscript

Abstract

With the recent emergence of percutaneous balloon compression (PBC) as a promising treatment for trigeminal neuralgia (TN), there is a growing need for research on its safety and efficacy. This study was designed to evaluate the safety and efficacy of PBC in the treatment of TN patients during the perioperative period. This study involved a total of 400 TN patients who were selected and treated with PBC at our institution. The clinical data and short-term outcomes were analyzed based on sex, initial PBC treatment for TN, and subsequent PBC treatment for recurrent TN after previous PBC or microvascular decompression (MVD) or radiofrequency thermocoagulation (RFT). No statistically significant difference was found when comparing postoperative pain relief between male and female patients with TN. Nevertheless, female patients were found to be more vulnerable than male patients to abnormal facial sensations (P = 0.001), diplopia (P = 0.015), postoperative headache (P = 0.012), and hyposmia (P = 0.029). Additionally, it was observed that there was no substantial difference in the postoperative pain relief rate between the first-time PBC group and PBC for recurrent TN patients postoperatively following procedures such as PBC, MVD, and RFT. In conclusion, this study has shown that PBC treatment is effective in managing TN in both males and females, regardless of whether the treatment was administered as a primary intervention or following prior surgical procedures such as PBC, MVD, or RFT. Nonetheless, it is noted that the risk of postoperative complications appears to be higher in female patients compared to male patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

Data availability

No datasets were generated or analysed during the current study.

References

  1. Tohyama S, Hung PS, Cheng JC, Zhang JY, Halawani A, Mikulis DJ, Oh J, Hodaie M (2020) Trigeminal neuralgia associated with a solitary pontine lesion: clinical and neuroimaging definition of a new syndrome. Pain 161(5):916–925. https://doi.org/10.1097/j.pain.0000000000001777

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Di Stefano G, Truini A, Cruccu G (2018) Current and innovative pharmacological options to treat typical and atypical trigeminal neuralgia. Drugs 78(14):1433–1442. https://doi.org/10.1007/s40265-018-0964-9

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Heinskou TB, Maarbjerg S, Wolfram F, Rochat P, Brennum J, Olesen J, Bendtsen L (2019) Favourable prognosis of trigeminal neuralgia when enrolled in a multidisciplinary management program - a two-year prospective real-life study. J Headache Pain 20(1):23. https://doi.org/10.1186/s10194-019-0973-4

    Article  PubMed  PubMed Central  Google Scholar 

  4. Obermann M (2010) Treatment options in trigeminal neuralgia. Ther Adv Neurol Disord 3(2):107–115. https://doi.org/10.1177/1756285609359317

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Urgosik D, Liscak R, Novotny J Jr, Vymazal J, Vladyka V (2005) Treatment of essential trigeminal neuralgia with gamma knife surgery. J Neurosurg 102:29–33. https://doi.org/10.3171/jns.2005.102.s_supplement.0029

    Article  PubMed  Google Scholar 

  6. Andersen ASS, Heinskou TB, Rochat P, Springborg JB, Noory N, Smilkov EA, Bendtsen L, Maarbjerg S (2022) Microvascular decompression in trigeminal neuralgia - a prospective study of 115 patients. J Headache Pain 23(1):145. https://doi.org/10.1186/s10194-022-01520-x

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Garcia-Isidoro S, Castellanos-Sanchez VO, Iglesias-Lopez E, Perpiña-Martinez S (2021) Invasive and non-invasive electrical neuromodulation in trigeminal nerve neuralgia: a systematic review and Meta-analysis. Curr Neuropharmacol 19(3):320–333. https://doi.org/10.2174/1570159X18666200729091314

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Li F, Han S, Ma Y, Yi F, Xu X, Liu Y (2014) Optimal duration of percutaneous microballoon compression for treatment of trigeminal nerve injury. Neural Regeneration Res 9(2):179–189. https://doi.org/10.4103/1673-5374.125347

    Article  Google Scholar 

  9. Santos VS, Santana JC, Castro FD, Oliveira LS, Santana JC, Feitosa VL, Gurgel RQ, Cuevas LE (2016) Pain and quality of life in leprosy patients in an endemic area of Northeast Brazil: a cross-sectional study. Infect Dis Poverty 5:18. https://doi.org/10.1186/s40249-016-0113-1

    Article  PubMed  PubMed Central  Google Scholar 

  10. Young JC, Wu JM, Willis-Gray M, Pate V, Jonsson Funk M (2020) Persistent opioid use after hysterectomy in the United States, 2005–2015. Obstet Gynecol 135(1):123–132. https://doi.org/10.1097/AOG.0000000000003612

    Article  PubMed  PubMed Central  Google Scholar 

  11. Liu KS, Kao CW, Tseng YY, Chen SK, Lin YT, Lu CJ, Liu SJ (2021) Assessment of Antimicrobial Agents, Analgesics, and Epidermal Growth Factors-Embedded Anti-Adhesive Poly(Lactic-Co-Glycolic Acid) Nanofibrous Membranes: In vitro and in vivo Studies. International journal of nanomedicine 16, 4471–4480. https://doi.org/10.2147/IJN.S318083

  12. Zheng X, Feng X, Cai XJ (2016) Effectiveness and safety of continuous wound infiltration for postoperative pain management after open gastrectomy. World J Gastroenterol 22(5):1902–1910. https://doi.org/10.3748/wjg.v22.i5.1902

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Xu B, Liu SS, Wei J, Jiao ZY, Mo C, Lv CM, Huang AL, Chen QB, Ma L, Guan XH (2020) Role of spinal cord Akt-mTOR signaling pathways in postoperative Hyperalgesia Induced by Plantar Incision in mice. Front NeuroSci 14:766. https://doi.org/10.3389/fnins.2020.00766

    Article  PubMed  PubMed Central  Google Scholar 

  14. Mao Z, Wen T, Liu X, Chen J, Hu P, Liu C, Liu H, Kang H, Zhang Z, Zhou F (2022) Geriatric nutritional risk index is Associated with Hospital Death in Elderly patients with multiple organ dysfunction syndrome: a retrospective study based on the MIMIC-III database. Front Nutr 9:834256. https://doi.org/10.3389/fnut.2022.834256

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Eslami V, Katz MJ, White RS, Sundermann E, Jiang JM, Ezzati A, Lipton RB (2017) Pain Intensity and Pain Interference in older adults: role of gender, obesity and high-sensitivity C-Reactive protein. Gerontology 63(1):3–12. https://doi.org/10.1159/000446651

    Article  PubMed  Google Scholar 

  16. Ge X, Wang L, Pan L, Ye H, Zhu X, Fan S, Feng Q, Yu W, Ding Z (2022) Amplitude of low-frequency fluctuation after a single-trigger pain in patients with classical trigeminal neuralgia. J Headache Pain 23(1):117. https://doi.org/10.1186/s10194-022-01488-8

    Article  PubMed  PubMed Central  Google Scholar 

  17. Zheng S, Yuan R, Ni J, Liu H, Yang Y, Zhang S, Li J (2022) Long-term recurrence-free survival and complications of percutaneous balloon compression and radiofrequency thermocoagulation of gasserian ganglion for trigeminal neuralgia: a retrospective study of 1313 cases. Pain Practice: Official J World Inst Pain 22(5):532–540. https://doi.org/10.1111/papr.13114

    Article  Google Scholar 

  18. Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition (2018) Cephalalgia: an international journal of headache 38(1), 1–211. https://doi.org/10.1177/0333102417738202

  19. Mullan S, Lichtor T (1983) Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg 59(6):1007–1012. https://doi.org/10.3171/jns.1983.59.6.1007

    Article  CAS  PubMed  Google Scholar 

  20. Wang CM, Guan ZY, Zhang J, Cai CH, Pang QG, Wang RW, Liu H, Liu YF, Yin MH, Ma Y (2015) Comparative study of trigeminocardiac reflex after trigeminal ganglion compression during total intravenous anesthesia. J Neurosurg Anesthesiol 27(1):16–20. https://doi.org/10.1097/ANA.0000000000000076

    Article  CAS  PubMed  Google Scholar 

  21. Rogers CL, Shetter AG, Fiedler JA, Smith KA, Han PP, Speiser BL (2000) Gamma knife radiosurgery for trigeminal neuralgia: the initial experience of the Barrow Neurological Institute. Int J Radiat Oncol Biol Phys 47(4):1013–1019. https://doi.org/10.1016/s0360-3016(00)00513-7

    Article  CAS  PubMed  Google Scholar 

  22. Fan X, Xu F, Ren H, Lu Z, Bu H, Ma L, Kong C, Wang T (2021) The analysis of Percutaneous Balloon Compression on Efficacy and negative emotion in the treatment of recurrent trigeminal Neuralgia after Surgical procedures. Pain Physician 24(8):E1255–E1262

    PubMed  Google Scholar 

  23. Sun C, Zheng W, Zhu Q, Du Q, Yu W (2022) The pros and cons of multiple puncture in percutaneous balloon compression for treatment of trigeminal neuralgia. Front Neurol 13:1034133. https://doi.org/10.3389/fneur.2022.1034133

    Article  PubMed  PubMed Central  Google Scholar 

  24. Wang JY, Bender MT, Bettegowda C (2016) Percutaneous procedures for the treatment of trigeminal Neuralgia. Neurosurg Clin North Am 27(3):277–295. https://doi.org/10.1016/j.nec.2016.02.005

    Article  Google Scholar 

  25. Kouzounias K, Schechtmann G, Lind G, Winter J, Linderoth B (2010) Factors that influence outcome of percutaneous balloon compression in the treatment of trigeminal neuralgia. Neurosurgery 67(4):925–934. https://doi.org/10.1227/NEU.0b0. 13e3181 e b5230

    Article  PubMed  Google Scholar 

  26. Skirving DJ, Dan NG (2001) A 20-year review of percutaneous balloon compression of the trigeminal ganglion. J Neurosurg 94(6):913–917. https://doi.org/10.3171/jns.2001.94.6.0913

    Article  CAS  PubMed  Google Scholar 

  27. Lone PA, Wani NA, Ain QU, Heer A, Devi R, Mahajan S (2021) Common postoperative complications after general anesthesia in oral and maxillofacial surgery. Natl J Maxillofacial Surg 12(2):206–210. https://doi.org/10.4103/njms.NJMS_66_20

    Article  Google Scholar 

  28. Asplund P, Linderoth B, Bergenheim AT (2010) The predictive power of balloon shape and change of sensory functions on outcome of percutaneous balloon compression for trigeminal neuralgia. J Neurosurg 113(3):498–507. https://doi.org/10.3171/2010.2.JNS091466

    Article  PubMed  Google Scholar 

  29. Wang Q, Chen C, Guo G, Li Z, Huang D, Zhou H (2021) A Prospective Study to Examine the Association of the Foramen Ovale Size with Intraluminal pressure of Pear-shaped balloon in Percutaneous Balloon Compression for Trigeminal Neuralgia. Pain Therapy 10(2):1439–1450. https://doi.org/10.1007/s40122-021-00311-7

    Article  PubMed  PubMed Central  Google Scholar 

  30. Zhang H, Lian Y, Ma Y, Chen Y, He C, Xie N, Wu C (2014) Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind, placebo-controlled trial. J Headache Pain 15(1):65. https://doi.org/10.1186/1129-2377-15-65

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Omeis I, Smith D, Kim S, Murali R (2008) Percutaneous balloon compression for the treatment of recurrent trigeminal neuralgia: long-term outcome in 29 patients. Stereotact Funct Neurosurg 86(4):259–265. https://doi.org/10.1159/000138770

    Article  PubMed  Google Scholar 

  32. Chen JF, Tu PH, Lee ST (2012) Repeated percutaneous balloon compression for recurrent trigeminal neuralgia: a long-term study. World Neurosurg 77(2):352–356. https://doi.org/10.1016/j.wneu.2011.06.013

    Article  ADS  PubMed  Google Scholar 

  33. Chen JN, Yu WH, Du HG, Jiang L, Dong XQ, Cao J (2018) Prospective comparison of Redo Microvascular Decompression and Percutaneous Balloon Compression as primary surgery for recurrent trigeminal neuralgia. J Korean Neurosurg Soc 61(6):747–752. https://doi.org/10.3340/jkns.2017.0196

    Article  PubMed  PubMed Central  Google Scholar 

  34. Bakker NA, Van Dijk JM, Immenga S, Wagemakers M, Metzemaekers JD (2014) Repeat microvascular decompression for recurrent idiopathic trigeminal neuralgia. J Neurosurg 121(4):936–939. https://doi.org/10.3171/2014.7.JNS132667

    Article  PubMed  Google Scholar 

  35. Liu L, Sun Z, Zhang Y, Ma G, Luo F (2022) Predictors of response for percutaneous balloon compression for the treatment of recurrent trigeminal neuralgia following surgical procedures: a retrospective study. Neurosurg Rev 45(5):3447–3455. https://doi.org/10.1007/s10143-022-01852-x

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We express our gratitude to participants and researchers in this study.

Funding

This study was supported by Liaoning Natural Science Foundation of China (No. 2020-MS-053).

Author information

Authors and Affiliations

  1. Dalian Medical University, Dalian, Liaoning Province, China

    Qianqian Tang & Shihui Gao

  2. Department of Anesthesiology, People’s Hospital of China Medical University (People’s Hospital of Liaoning Province), Shenyang, China

    Qianqian Tang, Shihui Gao, Changming Wang & Jing Zhang

  3. Department of Anesthesiology, Jinan Eighth Hospital, Shandong, China

    Kai Zheng

  4. Department of Neurosurgery II, People’s Hospital of China Medical University (People’s Hospital of Liaoning Province), Shenyang, China

    Haitao Huang, Yanfeng Li & Yi Ma

Authors
  1. Qianqian Tang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shihui Gao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Changming Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kai Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jing Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Haitao Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yanfeng Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Yi Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

All authors contributed to the study conception and design. The work was designed by C.W. and K.Z. Material preparation and data collection were performed by Q.T., H.H., Y.L. and Y.M. The interpretation of data was performed by J.Z. and C.W. The first draft of the manuscript was written by Q.T. and S.G., and all authors commented on the previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Changming Wang or Kai Zheng.

Ethics declarations

Ethical approval

This study was performed in line with the principles of the Declaration of Helsinki. All research procedures were approved by the Institutional Research Review Board and the Research Ethics Committee of The People’s Hospital of Liaoning Province. Patient’s personal sensitive information has been anonymized and deidentifed.

Consent to participate

All patients who participated in the study signed informed consent.

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tang, Q., Gao, S., Wang, C. et al. A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis. Neurosurg Rev 47, 86 (2024). https://doi.org/10.1007/s10143-024-02323-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10143-024-02323-1

Keywords

Search

Navigation