Abstract
Described here is the case of a 23-year-old male with Acinetobacter baumannii sepsis and acute renal failure requiring continuous venovenous hemodialysis treated successfully with intravenous polymyxin B. The drug was administered as a loading dose of 2.5 mg/kg, followed by 2 doses of 1 mg/kg on days 4 and 8, then 0.8 mg/kg daily to complete a 24-day course. A discussion of dosing recommendations for polymyxins in dialysis is presented.
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Sarria, J.C., Angulo-Pernett, F., Kimbrough, R.C. et al. Use of Intravenous Polymyxin B During Continuous Venovenous Hemodialysis. Eur J Clin Microbiol Infect Dis 23, 340–341 (2004). https://doi.org/10.1007/s10096-004-1106-8
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DOI: https://doi.org/10.1007/s10096-004-1106-8