Abstract
Presented here is a case of necrotizing fasciitis that developed bilaterally on the thighs of a 54-year-old diabetic woman following subcutaneous insulin injection. Severe localized pain was the presenting symptom; later, soft-tissue gas appeared. Incisional biopsy, performed on day 10 following admission, confirmed the diagnosis. Staphylococcus aureus was the only pathogen isolated. The disease had a slowly progressive course despite appropriate medical treatment, and recovery of the patient was achieved only after fasciotomy, drainage, and debridement of necrotic tissue was undertaken 4 weeks following admission. Staphylococcus aureus may cause subacute necrotizing fasciitis, and infection with this organism should be considered in cases of soft-tissue infection with gas formation in diabetics. The development of soft-tissue infection at the site of insulin injection should alert physicians to the possibility of infection with Staphylococcus aureus.
Similar content being viewed by others
References
Wilkerson R, Paull W, Coville FV (1987) Necrotizing fasciitis. Review of the literature and case report. Clin Orthop 216:187–192
Stamenkovic I, Lew PD (1984) Early recognition of potentially fatal necrotizing fasciitis. The use of frozen-section biopsy. N Engl J Med 310:1689–1693
Chelsom J, Halstensen A, Haga T, Hoiby EA (1994) Necrotizing fasciitis due to group A streptococci in western Norway: incidence and clinical features. Lancet 344:1111–1115
Wang KC, Shih CH (1992) Necrotizing fasciitis of the extremities. J Trauma 32:179–182
McHenry CR, Piotrowski JJ, Petrinic D, Malangoni MA (1995) Determinants of mortality for necrotizing soft-tissue infections. Ann Surg 221:558–563
Fisher JR, Conway MJ, Takeshita RT, Sandoval MR (1979) Necrotizing fasciitis. Importance of roentgenographic studies for soft-tissue gas. JAMA 241:803–806
Guilliano A, Lewis F Jr, Hadley K, Blaisdell FW (1977) Bacteriology of necrotizing fasciitis. AM J Surg 134:52–57
Brook I, Frazier EH (1995) Clinical and microbiological features of necrotizing fasciitis. J Clin Microbiol 33:2382–2387
Regev A, Weinberger M, Fishman M, Samara Z, Pitlik SD (1998) Necrotizing fasciitis caused by Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 17:101–103
VanBeek A, Zook E, Yaw P, Gardner R, Smith R, Glover JL (1974) Proceedings: nonclostridial gas-forming infections. A collective review and report of seven cases. Arch Surg 108:552–557
Bessman AN, Wagner W (1975) Nonclostridial gas gangrene. Report of 48 cases and review of the literature. JAMA 233:958–963
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Saliba, W.R., Goldstein, L.H., Raz, R. et al. Subacute Necrotizing Fasciitis Caused by Gas-Producing Staphylococcus aureus . Eur J Clin Microbiol Infect Dis 22, 612–614 (2003). https://doi.org/10.1007/s10096-003-1023-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10096-003-1023-2