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Subacute Necrotizing Fasciitis Caused by Gas-Producing Staphylococcus aureus

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Abstract

Presented here is a case of necrotizing fasciitis that developed bilaterally on the thighs of a 54-year-old diabetic woman following subcutaneous insulin injection. Severe localized pain was the presenting symptom; later, soft-tissue gas appeared. Incisional biopsy, performed on day 10 following admission, confirmed the diagnosis. Staphylococcus aureus was the only pathogen isolated. The disease had a slowly progressive course despite appropriate medical treatment, and recovery of the patient was achieved only after fasciotomy, drainage, and debridement of necrotic tissue was undertaken 4 weeks following admission. Staphylococcus aureus may cause subacute necrotizing fasciitis, and infection with this organism should be considered in cases of soft-tissue infection with gas formation in diabetics. The development of soft-tissue infection at the site of insulin injection should alert physicians to the possibility of infection with Staphylococcus aureus.

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Correspondence to W. R. Saliba.

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Saliba, W.R., Goldstein, L.H., Raz, R. et al. Subacute Necrotizing Fasciitis Caused by Gas-Producing Staphylococcus aureus . Eur J Clin Microbiol Infect Dis 22, 612–614 (2003). https://doi.org/10.1007/s10096-003-1023-2

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