Abstract
The primary role of magnetic resonance imaging (MRI) in the evaluation of patients with parkinsonian syndromes is traditionally thought to be the differentiation between neurodegenerative and symptomatic parkinsonisms. Non conventional MRI techniques, however, could improve the clinical diagnosis by detecting ultrastructural damage even in brain regions not suspected to be involved. Moreover, functional MRI provides useful information upon the pathophysiology of Parkinson’s disease.
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References
Eckert T, Sailer M, Kaufmann J et al (2004) Differentiation of idiopathic Parkinson’s disease, multiple system atrophy, progressive supranuclear palsy, and healthy controls using magnetization transfer imaging. Neuroimage 21:229–235
Chan LL, Rumpel H, Yap K et al (2007) Case control study of diffusion tensor imaging in Parkinson’s disease. J Neurol Neurosurg Psychiatry 78:1383–1386
Blain CR, Barker GJ, Jarosz JM et al (2006) Measuring brain stem and cerebellar damage in parkinsonian syndromes using diffusion tensor MRI. Neurology 67:2199–2205
Ito M, Watanabe H, Kawai Y et al (2007) Usefulness of combined fractional anisotropy and apparent diffusion coefficient values for detection of involvement in multiple system atrophy. J Neurol Neurosurg Psychiatry 78:722–728
Watanabe H, Fukatsu H, Katsuno M et al (2004) Multiple regional 1H-MR spectroscopy in multiple system atrophy: NAA/Cr reduction in pontine base as a valuable diagnostic marker. J Neurol Neurosurg Psychiatry 75:103–109
Seppi K, Schocke MF (2005) An update on conventional and advanced magnetic resonance imaging techniques in the differential diagnosis of neurodegenerative parkinsonism. Curr Opin Neurol 18:370–375
Rango M, Arighi A, Biondetti P et al (2007) Magnetic resonance spectroscopy in Parkinson’s disease and parkinsonian syndromes. Funct Neurol 22:75–79
Federico F, Simone IL, Lucivero V et al (1999) Usefulness of proton magnetic resonance spectroscopy in differentiating parkinsonian syndromes. Ital J Neurol Sci:20:223–229
Schocke MF, Seppi K, Esterhammer R et al (2004) Trace of diffusion tensor differentiates the Parkinson variant of multiple system atrophy and Parkinson’s disease. Neuroimage 21:1443–1451
Brenneis C, Egger K, Scherfler C et al (2007) Progression of brain atrophy in multiple system atrophy. A longitudinal VBM study. J Neurol 254:191–196
Nandhagopal R, McKeown MJ, Stoessl AJ (2008) Functional imaging in Parkinson disease. Neurology 70:1478–1488
Yu H, Sternad D, Corcos DM, Vaillancourt DE (2007) Role of hyperactive cerebellum and motor cortex in Parkinson’s disease. Neuroimage 35:222–233
Grafton ST (2004) Contributions of functional imaging to understanding parkinsonian symptoms. Curr Opin Neurobiol 14:715–719
Rowe J, Stephan KE, Friston K et al (2002) Attention to action in Parkinson’s disease: impaired effective connectivity among frontal cortical regions. Brain 125:276–289
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Federico, F., Mezzapesa, D.M. & Petruzzellis, M. Parkinsonian syndromes. Neurol Sci 29 (Suppl 3), 308–310 (2008). https://doi.org/10.1007/s10072-008-1004-4
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DOI: https://doi.org/10.1007/s10072-008-1004-4