Skip to main content
SpringerLink
Log in

Evaluation of pulmonary function and bicycle ergometry tests in patients with Behçet’s disease

  • Original Article
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Behçet’s disease (BD) has well-defined pulmonary complications, but cardiopulmonary exercise testing and the strength of the respiratory muscles have not been studied in detail. We aimed to investigate the pulmonary functions tests, inspiratory and expiratory muscle strength and endurance, cardiopulmonary exercise test response, and the relationship of these parameters in patients with BD. Forty BD patients and 20 healthy control subjects were recruited for this study. Mean age was 32.95 ± 7.66 years for the BD group and 33.85 ± 6.63 years for the control group with no statistically significant difference. The ratios of slight obstructive ventilatory impairment were 32.5% for the BD group. When the values of pulmonary function tests were compared, no statistically significant difference was found in FEV1/FVC (Forced expiratory volume during the first second/forced vital capacity), or maximal midexpiratory flow rate (all in percent) values between patient and control groups. Maximal inspiratory and expiratory pressures, peak expiratory flow rate (in percent) and maximal voluntary ventilation (in percent) values were significantly lower than those of the control group. Body’s consumption of peak oxygen (VO2peak), oxygen consumption (milliliters per kilogram per minute), anaerobic threshold (AT), maximum exercise ventilation (VEmax), work load values, and exercise test time in the bicycle exercise test were significantly higher in control groups than in patients with BD. The values of heart rate reserve, breathing reserve, and VE/VCO2 at the AT of BD patients were within normal limits We conclude that respiratory and aerobic exercise may be recommended to improve respiratory muscle strength and endurance as well as the aerobic capacity and maximal ventilatory capacity in patients with BD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Ghate VJ, Jorizzo JL (2001) Behçet’s Disease. In: Kelley’s textbook of rheumatology, 6th edn. Saunders, Philadelphia, PA, pp 1205–1209

    Google Scholar 

  2. Gunen H, Evereklioglu C, Kosar F (2000) Thoracic involvement in Behçet’s disease and its correlation with multiple parameters. Lung 178:161–170

    Article  PubMed  CAS  Google Scholar 

  3. Eftimiou J, Johnston C, Spiro G (1986) Pulmonary disease in Behçet’s syndrome. Q J Med 58:259–280

    Google Scholar 

  4. Sharma OP (2001) Unusual systemic disorders associated with interstitial lung disease. Curr Opin Pulm Med 7(5):291–294

    Article  PubMed  CAS  Google Scholar 

  5. Erkan F, Cavdar T (1992) Pulmonary vasculitis in Behçet’s disease. Am Rev Respir Dis 146:232–239

    PubMed  CAS  Google Scholar 

  6. Uysal H, Balevi S, Okudan N, Gokbel H (2004) The relationship between HRCT and pulmonary function in Behçet’s disease. Lung 182:9–14

    Article  PubMed  CAS  Google Scholar 

  7. Feyza E (1999) Pulmonary involvement in Behçet’s disease. Curr Opin Pulm Med 5(5):314–318

    Article  Google Scholar 

  8. DeRemee RA (1998) Pulmonary vasculitis. In: Fishman AP (ed) Fishman’s pulmonary diseases and disorders, 3rd edn. McGraw-Hill Professional, New York, pp 1357–1374

    Google Scholar 

  9. Tunac A, Berkmen YM, Gökmen E (1995) Thoracic involvement in Behçet’s disease : pathologic, clinical, and imaging features. AJR Am J Roentgenol 164:51–56

    PubMed  Google Scholar 

  10. Evans WV, Jenkins RM (1979) Pulmonary function in Bechcet’s syndrome. Scand J Respir Dis 60:314–316

    PubMed  CAS  Google Scholar 

  11. Weber KT (1998) Principles and applications of cardiopulmonary exercise testing. In: Fishman AP (ed) Fishman’s pulmonary diseases and disorders, 3rd edn. McGraw-Hill Professional, New York, pp 576–588

    Google Scholar 

  12. Ruppel G (1994) Lung volume tests. In: Ruppel G (eds) Manual of pulmonary function testing, 6th edn. Mosby, St. Louis, MO, pp 1–25

    Google Scholar 

  13. Celli BR (1989) Clinical and physiological evaluation of respiratory muscle function. Clin Chest Med 10:199–214

    PubMed  CAS  Google Scholar 

  14. Arora NS, Rochester DF (1982) Respiratory muscle strength and maximal voluntary ventilation in undernourished patients. Am Rev Respir Dis 126:5–8

    PubMed  CAS  Google Scholar 

  15. Ünlü M, Akıncıoglu C, Yamaç K, Önder M (2001) Pulmonary involvement in Behçet’s disease: evaluation of 123I-MIBG retention. Nucl Med Commun 22(10):1083–1088

    Article  PubMed  Google Scholar 

  16. Davies JD (1973) Behçet’s syndrome with haemoptysis and pulmonary lesions. J Pathol 109:351–356

    Article  PubMed  CAS  Google Scholar 

  17. Ahonen AV, Stenius-Aarniale BS, Viljanen BC (1978) Obstructive lung disease in Behçet’s syndrome. Scand J Respir Dis 59(1):44–50

    PubMed  CAS  Google Scholar 

  18. Dilsen N, Cavdar T, Aral O (1991) Pulmonary involvement in Behçet’s disease in Turkey. In: O’Duffy JD (ed) Behçet’s disease: basic and clinical aspects. McGraw-Hill Professional, New York, pp 195–203

  19. Rochester DF, Arora NS (1983) Respiratory muscle failure. Med Clin North Am 67:573–597

    PubMed  CAS  Google Scholar 

  20. Braun NMT, Arora NS, Rochester DF (1983) Respiratory muscle and pulmonary function in proximal myopathies. Thorax 38:616

    Article  PubMed  CAS  Google Scholar 

  21. Wasserman K (2005) Normal values. In: Principles of exercise testing and interpretation. Lippincott Williams & Wilkins, Philadelphia, PA, pp 160–182

    Google Scholar 

  22. Glass SC (2006) Cardiopulmonary adaptations to exercise. In: ACSM’s resource manual for guidelines for exercise testing and prescription, 5th edn. Lippincott Williams & Wilkins, Philadelphia, PA, pp 313–335

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. First Department of Physical Medicine and Rehabilitation, Ministry of Health Ankara Education and Research Hospital, 06340, Ankara, Turkey

    Figen Gökoğlu, Z. Rezan Yorgancioğlu, Nilgün Üstün & Figen Ayhan Ardiç

  2. Yunus Emre Caddesi 16/16, 06510, Etlik-Ankara, Turkey

    Figen Gökoğlu

Authors
  1. Figen Gökoğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Z. Rezan Yorgancioğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nilgün Üstün
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Figen Ayhan Ardiç
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Figen Gökoğlu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gökoğlu, F., Yorgancioğlu, Z.R., Üstün, N. et al. Evaluation of pulmonary function and bicycle ergometry tests in patients with Behçet’s disease. Clin Rheumatol 26, 1421–1425 (2007). https://doi.org/10.1007/s10067-006-0508-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-006-0508-7

Keywords

Search

Navigation