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Clinical application of artificial bone in the maxillofacial region

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Abstract

Hard tissue reconstruction is very useful for bony defects of the maxillofacial region. Autogenous bone, allogeneic bone, and artificial bone have been used to reconstruct maxillofacial bone; however, the use of autogenous bone involves high surgical invasiveness because of the need to harvest the bone. The use of allogeneic bone is associated with infections, raises ethical concerns, and is not widely used in Japan. Artificial bone has several advantages, including no need for bone harvesting, excellent biocompatibility, and a relatively easy surgical procedure. Use of artificial bone avoids the much greater invasiveness of harvesting bone, and several types of artificial bone have been developed. Design requirements for artificial bone include surgical manipulability, structural compatibility with the defective area, support properties, and the ability to induce bone regeneration; however, no artificial bone meeting all these requirements has yet been developed. Artificial bone is used in many patients in our medical center, and we have been active in developing the next generation of artificial bone with better properties. In this article, we present a case history and discuss the future development of artificial bone for use in maxillofacial reconstruction.

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Author notes

  1. Hideto Saijo

    Present address: Department of Oral-maxillofacial Surgery, Dentistry and Orthodontics, The University of Tokyo Hospital, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, Japan

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

    Hideto Saijo, Kazuyo Igawa, Yoshiyuki Mori, Daichi Chikazu, Mitsuyoshi Iino & Tsuyoshi Takato

  2. Division of Tissue Engineering, Faculty of Medicine, The University of Tokyo Hospital, Tokyo, Japan

    Ung-il Chung

Authors
  1. Hideto Saijo
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  2. Ung-il Chung
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  3. Kazuyo Igawa
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  4. Yoshiyuki Mori
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  5. Daichi Chikazu
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  6. Mitsuyoshi Iino
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  7. Tsuyoshi Takato
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Corresponding author

Correspondence to Hideto Saijo.

Additional information

This is an updated version of an article originally published in The Japanese Journal of Artificial Organs 2007;36:113–116

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Saijo, H., Chung, Ui., Igawa, K. et al. Clinical application of artificial bone in the maxillofacial region. J Artif Organs 11, 171–176 (2008). https://doi.org/10.1007/s10047-008-0425-4

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  • DOI: https://doi.org/10.1007/s10047-008-0425-4

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