Abstract
Substrate materials play a significant role in the improvement of electrochemical biosensors. In the present work, NiO nanoflake arrays were fully and uniformly decorated with Mn3O4 nanoparticles by stepwise method. The as-prepared samples were characterized by scanning electron microscopy (SEM), x-ray diffractionmeter (XRD), transmission electron microscopy (TEM), x-ray photoelectron spectroscopy (XPS), energy-dispersive x-ray spectroscopy (EDS), and chronoamperometry. Subsequently, the optimized Mn3O4 nanoparticle/NiO nanoflake arrays were employed as substrate to fabricate electrochemical biosensors for glucose determination. The results demonstrated that as-prepared glucose biosensors could achieve 226.2 μA mM−1 cm−2 of sensitivity and 1.0 μM of detection limit, respectively. In addition, the linear range was between 9.9 and 3665.0 μM. The developed substrate could also be extended to construct electrochemical biosensors based on other oxidase with excellent performance.
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Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE (2014) Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract 103(2):137–149
NCD Risk Factor Collaboration (2016) Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants. Lancet 387:1513–1530
Shao YY, Wang J, Wu H, Liu J, Aksay IA, Lin YH (2010) Graphene based electrochemical sensors and biosensors: a review. Electroanal 22(10):1027–1036
Wu P, Shao Q, Hu YJ, Jin J, Zhang H, Cai CX (2010) Direct electrochemistry of glucose oxidase assembled on graphene and application to glucose detection. Electrochim Acta 55(28):8606–8614
Song YJ, Qu KG, Zhao C, Ren JS, Qu XG (2010) Graphene oxide: intrinsic peroxidase catalytic activity and its application to glucose detection. Adv Mater 22(19):2206–2210
Wang XW, Dong XC, Wen YQ, Li CM, Xiong QH, Chen P (2012) A grapheme-cobalt oxide based needle electrode for non-enzymatic glucose detection in micro-droplets. Chem Commun 48(52):6490–6492
Song J, Xu L, Zhou CY, Xing RQ, Dai QL, Liu DL, Song HW (2013) Synthesis of graphene oxide based CuO nanoparticles composite electrode for highly enhanced nonenzymatic glucose detection. ACS Appl Mater Interfaces 5(24):12928–12934
Chen T, Li XW, Qiu CC, Zhu WC, Ma HY, Chen SH, Meng O (2014) Electrochemical sensing of glucose by carbon cloth-supported Co3O4/PbO2 core-shell nanorod arrays. Biosens Bioelectron 53:200–206
Wang L, Lu XP, Wen CJ, Xie YZ, Miao LF, Chen SH, Li HB, Li P, Song YH (2015) One-step synthesis of Pt-NiO nanoplate array/reduced graphene oxide nanocomposites for nonenzymatic glucose sensing. J Mater Chem A 3(2):608–616
Kim JY, Jo SY, Sun GJ, Katoch K, Choi SW, Kim SS (2014) Tailoring the surface area of ZnO nanorods for improved performance in glucose sensors. Sensors Actuators B Chem 192:216–220
Mandal S, Marie M, Manasreh O (2016) Fabrication of an electrochemical sensor for glucose detection using ZnO nanorods. MRS Adv 1(13):861–867
Ahmad R, Tripathy N, Par JH, Hahn YB (2015) A comprehensive biosensor integrated with a ZnO nanorod FET array for selective detection of glucose. Cholesterol and urea. Chem Commun 51(60):11968–11971
Gao ZD, Guo J, Shrestha NK, Hahn R, Song YY (2013) Nickel hydroxide nanoparticle activated semi-metallic TiO2 nanotube arrays for non-enzymatic glucose sensing. Chem Eur J 19(46):15530–15534
Cui HF, Zhang K, Zhang YF, Sun YL, Wang J, Zhang WD, Luong JHT (2013) Immobilization of glucose oxidase into a nanoporous TiO2 film layered on metallophthalocyanine modified vertically-aligned carbon nanotubes for efficient direct electron transfer. Biosens Bioelectron 46:113–118
Ci SQ, Huang TZ, Wen ZH, Cui SM, Mao S, Steeber DA, Chen JH (2014) Nickel oxide hollow microsphere for non-enzyme glucose detection. Biosens Bioelectron 54:251–257
Guo CY, Wang Y, Zhao YQ, Xu CL (2013) Non-enzymatic glucose sensor based on three dimensional nickel oxide for enhanced sensitivity. Anal Methods 5(7):1644–1647
Dung NQ, Patil D, Jung H, Kim J, Kim D (2013) NiO-decorated single-walled carbon nanotubes for high-performance nonenzymatic glucose sensing. Sensors Actuators B Chem 183:381–387
Chowdhury M, Cummings F, Kebede M, Fester V (2017) Binderless solution processed Zn doped Co3O4 film on FTO for rapid and selective non-enzymatic glucose detection. Electroanalysis 29(2):578–586
Zhao J, Dong WF, Zhang XD, Chai HX, Huang YM (2018) FeNPs@Co3O4 hollow nanocages hybrids as effective peroxidase mimics for glucose biosensing. Sensors Actuators B Chem 263:575–584
Guo CY, Zhang X, Huo HH, Xu CL, Han X (2013) Co3O4 microspheres with free-standing nanofibers for high performance non-enzymatic glucose sensor. Analyst 138(22):6727–6731
Yuan J, Cen Y, Kong XJ, Wu S, Liu CL, Yu RQ, Chu X (2015) MnO2-nanosheet-modified conversion nanosystem for sensitive turn-on fluorescence detection of H2O2 and glucose in blood. ACS Appl Mater Interfaces 7(19):10548–10555
Lee SH, Yang J, Han YJ, Cho M, Lee Y (2015) Rapid and highly sensitive MnOx nanorods array platform for a glucose analysis. Sensors Actuators B Chem 218:137–144
Patil D, Dung NQ, Jung H, Ahn SY, Jang DM, Kim D (2012) Enzymatic glucose biosensor based on CeO2 nanorods synthesized by non-isothermal precipitation. Biosens Bioelectron 31(1):176–181
Li SQ, Liu XD, Chai HX, Huang YM (2018) FeNPs@Co3O4 hollow nanocages hybrids as effective peroxidase mimics for glucose biosensing. Trends Anal Chem 105:391–403
Khun K, Ibupoto ZH, Liu X, Beni V, Willander M (2015) The ethylene glycol template assisted hydrothermal synthesis of Co3O4 nanowires; structural characterization and their application as glucose non-enzymatic sensor. Mater Sci Eng B 194:94–100
Wang GM, Lu XH, Zhai T, Ling YC, Wang HY, Tong YX, Li Y (2012) Free-standing nickel oxide nanoflake arrays: synthesis and application for highly sensitive non-enzymatic glucose sensors. Nanoscale 4(10):3123–3127
Toghill KE, Compton RG (2010) Electrochemical non-enzymatic glucose sensors: a perspective and an evaluation. Int J Electrochem Sci 5:1246–1301
Saha S, Arya SK, Singh SP, Sreenivas K, Malhotra BD, Gupta V (2009) Nanoporous cerium oxide thin film for glucose biosensor. Biosens Bioelectron 24(7):2040–2045
Han L, Shao CX, Liang B, Liu H (2016) Genetically engineered phage-templated MnO2 nanowires: synthesis and their application in electrochemical glucose biosensor operated at neutral pH condition. ACS Appl Mater Interfaces 8(22):13768–13776
Wang Y, Cui JW, Luo L, Zhang JC, Wang Y, Qin YQ, Zhang Y, Shu X, Lv J, Wu YC (2017) One-pot synthesis of NiO/Mn2O3 nanoflake arrays and their application in electrochemical biosensing. Appl Surf Sci 423:1182–1187
Thi TV, Rai AK, Gim J, Kim J (2015) High performance of Co-doped NiO nanoparticle anode material for rechargeable lithium ion batteries. J Power Sources 292:23–30
Lee JW, Hall AS, Kim JD, Mallouk TE (2012) A facile and template-free hydrothermal synthesis of Mn3O4 nanorods on graphene sheets for supercapacitor electrodes with long cycle stability. Chem Mater 24(6):1158–1164
Wang JG, Jin DD, Zhou R, Liu XR, Shen C, Xie KY, Li BH, Kang FY, Wei BQ (2016) Highly flexible graphene/Mn3O4 nanocomposite membrane as advanced nodes for Li-ion batteries. ACS Nano 10(6):6227–6234
Cui JW, Adeloju SB, Wu YC (2014) Integration of a highly ordered gold nanowires array with glucose oxidase for ultra-sensitive glucose detection. Anal Chim Acta 809:134–140
Sekar NC, Shaegh SAM, Ng SH, Ge LY, Tan SN (2014) A paper-based amperometric glucose biosensor developed with Prussian blue-modified screen-printed electrodes. Sensors Actuators B Chem 204:414–420
Pradhan D, Niroui F, Leung KT (2010) High-performance, flexible enzymatic glucose biosensor based on ZnO nanowires supported on a gold-coated polyester substrate. ACS Appl Mater Interfaces 8:2409–2412
Chu XF, Zhu XH, Dong YP, Chen TY, Ye MF, Sun WQ (2012) An amperometric glucose biosensor based on the immobilization of glucose oxidase on the platinum electrode modified with NiO doped ZnO nanorods. J Electroanal Chem 676:20–26
Cui JW, Luo JB, Peng BG, Zhang XY, Zhang Y, Wang Y, Qin YQ, Zheng HM, Shu X, Wu YC (2016) Synthesis of porous NiO/CeO2 hybrid nanoflake arrays as a platform for electrochemical biosensing. Nanoscale 8(2):770–774
Ju J, Chen W (2015) In situ growth of surfactant-free gold nanoparticles on nitrogen doped graphene quantum dots for electrochemical detection of hydrogen peroxide in biological environments. Anal Chem 87(3):1903–1910
Long GL, Winefordner JD (1983) Limit of detection. A closer look at the IUPAC definition. Anal Chem 55:712A–724A
Wang J (2008) Electrochemical glucose biosensors. Chem Rev 108(2):814–825
Li Y, Song YY, Yang C, Xia XH (2007) Hydrogen bubble dynamic template synthesis of porous gold for nonenzymatic electrochemical detection of glucose. Electrochem Commun 9(5):981–988
Funding
The authors appreciate the financial supports from National Natural Science Foundation of China (Nos. 51402081, 51502071, and 31501576) and Fundamental Research Funds for the Central Universities (No. JZ2017HGTB0203). The authors also would like to thank the financial support from the 111 Project (B18018).
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Wang, Y., Cui, J., Wang, Y. et al. Decorating Mn3O4 nanoparticle on NiO nanoflake arrays for high-performance electrochemical biosensors. J Solid State Electrochem 23, 135–142 (2019). https://doi.org/10.1007/s10008-018-4117-6
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DOI: https://doi.org/10.1007/s10008-018-4117-6