Abstract
Co(II) and Zn(II) binding constants have been measured for binding to the HIV-1 nucleocapsid N-terminal metal binding domain (residues 1–18), using competition titration methods and monitoring Co(II) binding by visible absorbance spectroscopy. Enthalpies for binding were directly measured by isothermal titration colorimetry. The results are compared with recent studies of related systems, including a study of Zn(II) binding by the full length protein.
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Received: 1 December 1998 / Accepted: 31 December 1998
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McLendon, G., Hull, H., Larkin, K. et al. Metal binding to the HIV nucleocapsid peptide. JBIC 4, 171–174 (1999). https://doi.org/10.1007/s007750050301
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DOI: https://doi.org/10.1007/s007750050301