Abstract
Depression during pregnancy has been associated with an increased risk of adverse outcomes for the infant such as preterm birth. These risks are not reduced with pharmacological treatment, but the effect of non-pharmacological therapies is unknown. We performed a systematic review to assess the risk of adverse perinatal outcomes in non-pharmacologically treated depressed women compared to non-depressed women. We found no studies that met our inclusion criteria, highlighting a critical need for research on this topic.
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References
Campagne DM (2007) Fact: antidepressants and anxiolytics are not safe during pregnancy. Eur J Obstet Gynecol Reprod Biol 135:145–148. doi:10.1016/j.ejogrb.2007.06.010
Chatillon O, Even C (2010) [Antepartum depression: prevalence, diagnosis and treatment]. Encéphale 36:443–451. doi:10.1016/j.encep.2010.02.004
Cohen LS et al (2006) Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment. JAMA 295:499–507. doi:10.1001/jama.295.5.499
Dennis C-L, Ross LE, Grigoriadis S (2007) Psychosocial and psychological interventions for treating antenatal depression. Cochrane Database Syst Rev:CD006309 doi:10.1002/14651858.CD006309.pub2
Goldenberg RL, Culhane JF, Iams JD, Romero R (2008) Epidemiology and causes of preterm birth. Lancet 371:75–84. doi:10.1016/s0140-6736(08)60074-4
Goodman JH (2009) Women's attitudes, preferences, and perceived barriers to treatment for perinatal depression. Birth 36:60–69. doi:10.1111/j.1523-536X.2008.00296.x
Grigoriadis S et al (2013) The impact of maternal depression during pregnancy on perinatal outcomes: a systematic review and meta-analysis. J Clin Psychiatry 74:e321–341. doi:10.4088/JCP.12r07968
Huang H, Coleman S, Bridge JA, Yonkers K, Katon W (2014) A meta-analysis of the relationship between antidepressant use in pregnancy and the risk of preterm birth and low birth weight. Gen Hosp Psychiatry 36:13–18. doi:10.1016/j.genhosppsych.2013.08.002
Spinelli MG et al (2013) A controlled clinical treatment trial of interpersonal psychotherapy for depressed pregnant women at 3 New York City sites. J Clin Psychiatry 74:393–399. doi:10.4088/JCP.12m07909
Valero De Bernabé J, Soriano T, Albaladejo R, Juarranz M, Calle ME, Martínez D, Domínguez-Rojas V (2004) Risk factors for low birth weight: a review. Eur J Obstet Gynecol Reprod Biol 116:3–15. doi:10.1016/j.ejogrb.2004.03.007
Yonkers KA et al (2011) Does antidepressant use attenuate the risk of a major depressive episode in pregnancy? Epidemiology 22:848–854. doi:10.1097/EDE.0b013e3182306847
Acknowledgments
JB holds the John D. Cameron Endowed Chair in the Genetic Determinants of Chronic Diseases, Department of Clinical Epidemiology and Biostatistics, McMaster University. SDM is supported by a Canadian Institutes of Health Research (CIHR) Tier II Canada Research Chair in Maternal and Child Obesity Prevention and Intervention, Sponsor Award #950-229920. DK is supported by a New Investigator Award (CIHR) and an Early Career Transition Award (Alberta Centre for Child, Family, and Community Research). RG is supported by an MCRI Career Development Award. None of the agencies had any influence on the design, analysis, interpretation, conclusions, or decision to publish this manuscript.+
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Jarde, A., Morais, M., Kingston, D. et al. Does non-pharmacological therapy for antenatal depression reduce risks for the infant?. Arch Womens Ment Health 19, 549–552 (2016). https://doi.org/10.1007/s00737-015-0577-1
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DOI: https://doi.org/10.1007/s00737-015-0577-1