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Hexafluoroacetone as Protecting and Activating Reagent. Glycosylated Malic, Citramalic, and Thiomalic Acid Derivatives, New Glycosylated Building Blocks for Drug Design [1]

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Summary.

Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH2 using hexafluoroacetone as protecting and activating reagent.

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Authors and Affiliations

  1. Department of Organic Chemistry, University of Leipzig, D-04103, Leipzig, Germany

    Christoph Böttcher, Jan Spengler & Klaus Burger

Authors
  1. Christoph Böttcher
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  2. Jan Spengler
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  3. Klaus Burger
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Corresponding author

Correspondence to Klaus Burger.

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Dedicated to Prof. Dr. Horst Wilde on the occasion of his 65th birthday

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Böttcher, C., Spengler, J. & Burger, K. Hexafluoroacetone as Protecting and Activating Reagent. Glycosylated Malic, Citramalic, and Thiomalic Acid Derivatives, New Glycosylated Building Blocks for Drug Design [1]. Monatshefte für Chemie 135, 1225–1242 (2004). https://doi.org/10.1007/s00706-004-0187-5

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  • DOI: https://doi.org/10.1007/s00706-004-0187-5

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