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First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles “Gazella dorcas” in the Sudan, 2016-2017

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Abstract

In May 2017, many free-ranging dorcas gazelles (Gazella dorcas) with suspected signs of peste des petits ruminants (PPR) were reported in Dinder National Park, South-Eastern Sudan. Peste des petits ruminants virus (PPRV) antigen and nucleic acid were detected in specimens from these gazelles using an immunocapture ELISA and a reverse transcription polymerase chain reaction (RT-PCR) assays. PPRV was also detected in four healthy semi-captive dorcas gazelles from two areas of Khartoum State. Phylogenetic analysis showed that these PPRV strains belonged to the lineage IV genotype. The present study demonstrates that gazelles are a potential wild small ruminant host for PPRV and may influence the epidemiology of PPR in the Sudan.

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Acknowledgements

We are grateful to Prof. Elsayed Elowni (University of Khartoum) and Prof. Satya Parida (The Pirbright Institute, UK) for their valuable comments, the staff of the General Directorate of the Epizootics Disease Control, Khartoum, Sudan, and the Kuku Zoo (Sudan University of Science and Technology) for their kind assistance with collection of samples.

Funding

The research in this study was partially funded by a project from the Food and Agriculture Organization (FAO) (Grant No. SUD/TCP/3504) in collaboration with the Central Veterinary Research Laboratory (CVRL), Soba, Khartoum, Sudan, and by a research project for N.A. Osman from the Republic of the Sudan, Sudanese Ministry of Higher Education and Scientific Research, Commission of Scientific Research and Innovation (Grant No. 2017/972).

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Author notes

  1. Rayan M. Asil and Nussieba A. Osman contributed equally to this work.

  2. Deceased: Abdelgadir Ballal.

Authors and Affiliations

  1. Department of Pathology, Parasitology and Microbiology, College of Veterinary Medicine, Sudan University of Science and Technology, P.O. Box 204, Kuku, Khartoum-North, Sudan

    Rayan M. Asil & Nussieba A. Osman

  2. Virology Department, Central Veterinary Research Laboratory (CVRL), Soba, P.O. Box 8067, Al Amarat, Khartoum, Sudan

    Rayan M. Asil, Wegdan H. Ali, Baraa A. Mohamed & Shaza M. Mutwakil

  3. Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover Foundation, Bünteweg 17, 30559, Hannover, Germany

    Martin Ludlow

  4. Viral Vaccine Production Department, Central Veterinary Research Laboratory (CVRL), Soba, P.O. Box 8067, Al Amarat, Khartoum, Sudan

    Abdelgadir Ballal & Saafass Alsarraj

Authors
  1. Rayan M. Asil
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  2. Martin Ludlow
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  3. Abdelgadir Ballal
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  4. Saafass Alsarraj
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  5. Wegdan H. Ali
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  6. Baraa A. Mohamed
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  7. Shaza M. Mutwakil
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  8. Nussieba A. Osman
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Contributions

RMA performed most of the laboratory work and data analysis. ML helped with data interpretation and revised and finalized the manuscript. SA, WHA, BAM and SMM also contributed to these laboratory studies. AB (deceased) also contributed to the design of this study and laboratory work. NAO was responsible for the design and supervision of this research project, data analysis and interpretation, sequence and phylogenetic analysis, and wrote and finalized the drafted manuscript.

Corresponding author

Correspondence to Nussieba A. Osman.

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All authors declare that they have no conflict of interest.

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This article does not contain any studies with animals performed by any of the authors.

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Asil, R.M., Ludlow, M., Ballal, A. et al. First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles “Gazella dorcas” in the Sudan, 2016-2017. Arch Virol 164, 2537–2543 (2019). https://doi.org/10.1007/s00705-019-04330-w

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  • DOI: https://doi.org/10.1007/s00705-019-04330-w

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