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Genomic structure of the Aeromonas bacteriophage pAh6-C and its comparative genomic analysis

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Abstract

pAh6-C is a virulent bacteriophage (phage), isolated from a river in Korea, that infects a multiple-antibiotic-resistant A. hydrophila strain, JUNAH. The double-stranded DNA genome of pAh6-C is composed of 53,744 bp with a G + C content of 52.83 %. The genome encodes 86 putative ORFs, four putative promoters, and seven transcriptional terminator regions. Genome sequence analysis of pAh6-C and comparative analysis with the homologous Shewanella phage Spp001 revealed that there is a high degree of similarity between pAh6-C and Spp001 in 50 of the 86 ORFs of pAh6-C. The results of this investigation indicate that pAh6-C is closely related to Spp001, especially in the genes coding for proteins involved in DNA metabolism.

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Acknowledgements

This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2013R1A1A2006794).

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Authors and Affiliations

  1. Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Former American Base of Gournes, Heraklion, 71003, Crete, Greece

    Jin Woo Jun

  2. Laboratory of Aquatic Biomedicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, 151-742, Republic of Korea

    Hyoun Joong Kim, Sae Kil Yun & Se Chang Park

  3. Departments of Rheumatology, Bundang Jesaeng Hospital, Seongnam, 463-774, Republic of Korea

    Ji Young Chai

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  1. Jin Woo Jun
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  2. Hyoun Joong Kim
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  3. Sae Kil Yun
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  5. Se Chang Park
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Correspondence to Se Chang Park.

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Jun, J.W., Kim, H.J., Yun, S.K. et al. Genomic structure of the Aeromonas bacteriophage pAh6-C and its comparative genomic analysis. Arch Virol 160, 561–564 (2015). https://doi.org/10.1007/s00705-014-2221-1

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  • DOI: https://doi.org/10.1007/s00705-014-2221-1

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