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Complete sequence and genetic characterization of pigeon avian nephritis virus, a member of the family Astroviridae

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Abstract

In the current study, the complete genome sequence of a member of the family Astroviridae isolated from pigeons was determined through genetic characterization and phylogeny analysis. The isolated genome sequence was proposed to be that of pigeon avian nephritis virus (ANV), whose genome structure and characteristics were similar to previously reported avian astroviruses. The sequenced ssRNA genome comprises 6928 nucleotides, excluding the poly(A) tail, and contains three open reading frames. Phylogenetic analysis using a partial nucleotide sequence of the polymerase gene and the entire amino acid sequence of the full-length capsid protein revealed that pigeon avian nephritis virus is closely related to the previously published ANV, especially to the Japanese G-4260 and Chinese strains. This investigation provides information on the sequence and genetic characteristics of this virus and contributes to a better understanding of pigeon ANV and the possible occurrence of astrovirus transmission between chickens and pigeons.

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Acknowledgments

The authors thank Dr Yu-hong Su for providing statistical analysis and excellent technical assistance. The diarrhoeic stool samples from pigeons were kindly provide by the Animal Center for Disease Control in Shanghai, China.

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Authors and Affiliations

  1. Group of Zoonosis and Comparative Medicine, School of Agriculture and Biology, Shanghai Jiaotong University, Room 3-217, Biulding of Agriculture and Biology, 800 Dongchuan Road, Shanghai, 200240, People’s Republic of China

    W. Zhao, A. L. Zhu, Y. Yu, C. L. Yuan, C. X. Zhu, Z. B. Yang, L. Cui & X. G. Hua

  2. Department of Laboratory Animal, LiaoNing Medical University, Jinzhou, 121200, Liaoning, People’s Republic of China

    W. Zhao

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  1. W. Zhao
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  2. A. L. Zhu
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  3. Y. Yu
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  4. C. L. Yuan
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  5. C. X. Zhu
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  6. Z. B. Yang
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  7. L. Cui
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  8. X. G. Hua
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Correspondence to X. G. Hua.

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Zhao, W., Zhu, A.L., Yu, Y. et al. Complete sequence and genetic characterization of pigeon avian nephritis virus, a member of the family Astroviridae . Arch Virol 156, 1559–1565 (2011). https://doi.org/10.1007/s00705-011-1034-8

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  • DOI: https://doi.org/10.1007/s00705-011-1034-8

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