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Seeking a fine balance between effective antithrombotic prophylaxis and safety drug profile in the elderly population: the special case of traumatic brain injury

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Data Availability

All data mentioned in this manuscript have been either extracted from Laic et al. [10] or are retrievable from the public repositories of the US National Library of Medicine, including: pubmed.ncbi.nlm.nih.gov and pubmed.ncbi.nlm.nih.gov.

References

  1. Brown JD, Goodin AJ, Lip GYH, Adams VR (2018) Risk stratification for bleeding complications in patients with venous thromboembolism: application of the HAS-BLED bleeding score during the first 6 months of anticoagulant treatment. J Am Heart Assoc 7(6):e007901. https://doi.org/10.1161/JAHA.117.007901

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Chibbaro S, Cebula H, Todeschi J, Fricia M, Vigouroux D, Abid H, Kourbanhoussen H, Pop R, Nannavecchia B, Gubian A, Prisco L, Ligarotti GKI, Proust F, Ganau M (2018) Evolution of prophylaxis protocols for venous thromboembolism in neurosurgery: results from a prospective comparative study on low-molecular-weight heparin, elastic stockings, and intermittent pneumatic compression devices. World Neurosurg 109:e510–e516. https://doi.org/10.1016/j.wneu.2017.10.012

    Article  PubMed  Google Scholar 

  3. Clark D, Joannides A, Adeleye AO, Bajamal AH, Bashford T, Biluts H, Budohoski K, Ercole A, Fernández-Méndez R, Figaji A, Gupta DK, Härtl R, Iaccarino C, Khan T, Laeke T, Rubiano A, Shabani HK, Sichizya K, Tewari M, Tirsit A, Thu M, Tripathi M, Trivedi R, Devi BI, Servadei F, Menon D, Kolias A, Hutchinson P, Global Neurotrauma Outcomes Study collaborative (2022) Casemix, management, and mortality of patients rreseceiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study. Lancet Neurol 21(5):438–449. https://doi.org/10.1016/S1474-4422(22)00037-0

    Article  PubMed  Google Scholar 

  4. Dasic D, Morgan L, Panezai A, Syrmos N, Ligarotti GKI, Zaed I, Chibbaro S, Khan T, Prisco L, Ganau M (2022) A scoping review on the challenges, improvement programs, and relevant output metrics for neurotrauma services in major trauma centers. Surg Neurol Int 13:171. https://doi.org/10.25259/SNI_203_2022

    Article  PubMed  PubMed Central  Google Scholar 

  5. Del Brutto VJ, Chaturvedi S, Diener HC, Romano JG, Sacco RL (2019) Antithrombotic therapy to prevent recurrent strokes in ischemic cerebrovascular disease: JACC scientific expert panel. J Am Coll Cardiol 74(6):786–803. https://doi.org/10.1016/j.jacc.2019.06.039

    Article  PubMed  PubMed Central  Google Scholar 

  6. Ganau M, Lavinio A, Prisco L (2018) Delirium and agitation in traumatic brain injury patients: an update on pathological hypotheses and treatment options. Minerva Anestesiol 84(5):632–640. https://doi.org/10.23736/S0375-9393.18.12294-2

    Article  PubMed  Google Scholar 

  7. Ganau M, Prisco L, Cebula H, Todeschi J, Abid H, Ligarotti G, Pop R, Proust F, Chibbaro S (2017) Risk of deep vein thrombosis in neurosurgery: state of the art on prophylaxis protocols and best clinical practices. J Clin Neurosci 45:60–66. https://doi.org/10.1016/j.jocn.2017.08.008

    Article  PubMed  Google Scholar 

  8. Hijazi Z, Oldgren J, Lindbäck J, Alexander JH, Alings M, De Caterina R, Eikelboom JW, Ezekowitz MD, Held C, Huber K, Hylek EM, Granger CB, Lopes RD, Vinereanu D, Siegbahn A, Wallentin L (2020) Evaluation of the age, biomarkers, and clinical history-bleeding risk score in patients with atrial fibrillation with combined aspirin and anticoagulation therapy enrolled in the ARISTOTLE and RE-LY trials. JAMA Netw Open 3(9):e2015943. https://doi.org/10.1001/jamanetworkopen.2020.15943

    Article  PubMed  PubMed Central  Google Scholar 

  9. Ho KH, van Hove M, Leng G (2020) Trends in anticoagulant prescribing: a review of local policies in English primary care. BMC Health Serv Res 20(1):279. https://doi.org/10.1186/s12913-020-5058-1

    Article  PubMed  PubMed Central  Google Scholar 

  10. Laic RAG, Verhamme P, Vander Sloten J, Depreitere B (2023) Long-term outcomes after traumatic brain injury in elderly patients on antithrombotic therapy. Acta Neurochir (Wien) 165(5):1297–1307. https://doi.org/10.1007/s00701-023-05542-5

    Article  PubMed  Google Scholar 

  11. Maas AI, Hukkelhoven CW, Marshall LF, Steyerberg EW (2005) Prediction of outcome in traumatic brain injury with computed tomographic characteristics: a comparison between the computed tomographic classification and combinations of computed tomographic predictors. Neurosurgery 57(6):1173–1182. https://doi.org/10.1227/01.neu.0000186013.63046.6b

    Article  PubMed  Google Scholar 

  12. Marshall LF, Marshall SB, Klauber MR, Van Berkum CM, Eisenberg H, Jane JA, Luerssen TG, Marmarou A, Foulkes MA (1992) The diagnosis of head injury requires a classification based on computed axial tomography. J Neurotrauma 9(Suppl 1):S287–S292

    PubMed  Google Scholar 

  13. Previtali E, Bucciarelli P, Passamonti SM, Martinelli I (2011) Risk factors for venous and arterial thrombosis. Blood Transfus 9(2):120–138. https://doi.org/10.2450/2010.0066-10

    Article  PubMed  PubMed Central  Google Scholar 

  14. Prisco L, Iscra F, Ganau M, Berlot G (2012) Early predictive factors on mortality in head injured patients: a retrospective analysis of 112 traumatic brain injured patients. J Neurosurg Sci 56(2):131–136

    CAS  PubMed  Google Scholar 

  15. Toorop MMA, van Rein N, Nierman MC, Vermaas HW, Huisman MV, van der Meer FJM, Cannegieter SC, Lijfering WM (2020) Switching from vitamin K antagonists to direct oral anticoagulants: treatment satisfaction and patient concerns. J Thromb Haemost 18(6):1390–1397. https://doi.org/10.1111/jth.14793

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Yeh RW, Secemsky EA, Kereiakes DJ, Normand SL, Gershlick AH, Cohen DJ, Spertus JA, Steg PG, Cutlip DE, Rinaldi MJ, Camenzind E, Wijns W, Apruzzese PK, Song Y, Massaro JM, Mauri L, DAPT Study Investigators (2016) Development and validation of a prediction rule for benefit and harm of dual antiplatelet therapy beyond 1 year after percutaneous coronary intervention. JAMA 315(16):1735–1749. https://doi.org/10.1001/jama.2016.3775

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. School of Medicine, University of Cagliari, Cagliari, Italy

    Laura Ganau

  2. School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Nikolaos Syrmos

  3. Institute of Aerospace Medicine, Milan, Italy

    Gianfranco K. I. Ligarotti

  4. Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK

    Mario Ganau

Authors
  1. Laura Ganau
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  2. Nikolaos Syrmos
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  3. Gianfranco K. I. Ligarotti
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  4. Mario Ganau
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Correspondence to Mario Ganau.

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Ganau, L., Syrmos, N., Ligarotti, G.K.I. et al. Seeking a fine balance between effective antithrombotic prophylaxis and safety drug profile in the elderly population: the special case of traumatic brain injury. Acta Neurochir 165, 2215–2218 (2023). https://doi.org/10.1007/s00701-023-05699-z

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