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Sinking skin flap syndrome visualized by upright computed tomography

  • Case Report - Neurosurgery general
  • Published:
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Abstract

Sinking skin flap syndrome is a craniectomy complication characterized by new neurological dysfunction that typically worsens in the upright position and improves after cranioplasty. We present a 33-year-old man who experienced hemiparesis in the upright position after craniectomy. Upright computed tomography (CT) before cranioplasty showed a remarkable shift of the brain compared to supine CT. After cranioplasty, both symptoms and brain shift on CT resolved. Upright CT enables detection and objective evaluation of paradoxical herniation and midline shift that is not obvious on supine imaging modalities. Clinicians need to be aware of positional brain shift in postcraniectomy patients.

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Abbreviations

CSF:

Cerebrospinal fluid

CT:

Computed tomography

ICP:

Intracranial pressure

SSFS:

Sinking skin flap syndrome

References

  1. Andresen M, Juhler M (2014) Intracranial pressure following complete removal of a small demarcated brain tumor: a model for normal intracranial pressure in humans. J Neurosurg 121:797–801

    Article  Google Scholar 

  2. Annan M, De Toffol B, Hommet C, Mondon K (2015) Sinking skin flap syndrome (or syndrome of the trephined): a review. Br J Neurosurg 29:314–318

    Article  Google Scholar 

  3. Ashayeri K, Jackson EM, Huang J, Brem H, Gordon CR (2016) Syndrome of the trephined: a systematic review. Neurosurgery 79:525–534

    Article  Google Scholar 

  4. Di Rienzo A, Colasanti R, Gladi M, Pompucci A, Della Costanza M, Paracino R, Esposito D, Iacoangeli M (2020) Sinking flap syndrome revisited: the who, when and why. Neurosurg Rev 43:323–335

  5. Epstein HM, Linde HW, Crampton AR, Ciric IS, Eckenhoff JE (1970) The vertebral venous plexus as a major cerebral venous outflow tract. Anesthesiology 32:332–337

    Article  CAS  Google Scholar 

  6. Grant FC, Norcross NC (1939) Repair of cranial defects by cranioplasty. Ann Surg 110:488–512

    Article  CAS  Google Scholar 

  7. Holmlund P, Johansson E, Qvarlander S, Wahlin A, Ambarki K, Koskinen LD, Malm J, Eklund A (2017) Human jugular vein collapse in the upright posture: implications for postural intracranial pressure regulation. Fluids Barriers CNS 14:17

    Article  Google Scholar 

  8. Jinzaki M, Yamada Y, Nagura T, Nakahara T, Yokoyama Y, Narita K, Ogihara N, Yamada M (2020) Development of upright computed tomography with area detector for whole-body scans: phantom study, efficacy on workflow, effect of gravity on human body, and potential clinical impact. Invest Radiol 55:73–83

  9. Lim J, Kwon HJ, Kim SH, Koh HS, Choi SW (2018) Early occurrence of sinking skin flap syndrome in a state of intracranial hypertension : case report. Clin Neuroradiol 28:297–300

    Article  Google Scholar 

  10. Magnaes B (1976) Body position and cerebrospinal fluid pressure. Part 2: clinical studies on orthostatic pressure and the hydrostatic indifferent point. J Neurosurg 44:698–705

    Article  CAS  Google Scholar 

  11. Monea AG, Verpoest I, Vander Sloten J, Van der Perre G, Goffin J, Depreitere B (2012) Assessment of relative brain-skull motion in quasistatic circumstances by magnetic resonance imaging. J Neurotrauma 29:2305–2317

    Article  Google Scholar 

  12. Petersen LG, Lawley JS, Lilja-Cyron A, Petersen JCG, Howden EJ, Sarma S, Cornwell WK 3rd, Zhang R, Whitworth LA, Williams MA, Juhler M, Levine BD (2019) Lower body negative pressure to safely reduce intracranial pressure. J Physiol 597:237–248

    Article  CAS  Google Scholar 

  13. Petersen LG, Ogoh S (2019) Gravity, intracranial pressure, and cerebral autoregulation. Physiol Rep 7:e14039

    Article  Google Scholar 

  14. Petersen LG, Petersen JC, Andresen M, Secher NH, Juhler M (2016) Postural influence on intracranial and cerebral perfusion pressure in ambulatory neurosurgical patients. Am J Physiol Regul Integr Comp Physiol 310:R100–R104

    Article  CAS  Google Scholar 

  15. Schnaudigel S, Preul C, Ugur T, Mentzel HJ, Witte OW, Tittgemeyer M, Hagemann G (2010) Positional brain deformation visualized with magnetic resonance morphometry. Neurosurgery 66:376–384

  16. Stiver SI, Wintermark M, Manley GT (2008) Reversible monoparesis following decompressive hemicraniectomy for traumatic brain injury. J Neurosurg 109:245–254

    Article  Google Scholar 

  17. Stok WJ, Karemaker JM, Berecki-Gisolf J, Immink RV, van Lieshout JJ (2019) Slow sinusoidal tilt movements demonstrate the contribution to orthostatic tolerance of cerebrospinal fluid movement to and from the spinal dural space. Physiol Rep 7:e14001

    Article  Google Scholar 

  18. Valdueza JM, von Munster T, Hoffman O, Schreiber S, Einhaupl KM (2000) Postural dependency of the cerebral venous outflow. Lancet 355:200–201

    Article  CAS  Google Scholar 

  19. Vasung L, Hamard M, Soto MCA, Sommaruga S, Sveikata L, Leemann B, Vargas MI (2016) Radiological signs of the syndrome of the trephined. Neuroradiology 58:557–568

    Article  Google Scholar 

  20. Yamada Y, Yamada M, Yokoyama Y, Tanabe A, Matsuoka S, Yuki Niijima KN, Nakahara T, Murata M, Fukunaga K, Chubachi S, Jinzaki M (2020) Differences in lung and lobe volumes between supine and standing positions scanned with conventional and newly developed 320-detector-row upright CT: intra-individual comparison. Respiration https://doi.org/10.1159/000507265

  21. Yamaura A, Makino H (1977) Neurological deficits in the presence of the sinking skin flap following decompressive craniectomy. Neurol Med Chir (Tokyo) 17:43–53

    Article  CAS  Google Scholar 

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Acknowledgments

The authors would like to thank Enago (www.enago.jp) for the English language review.

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Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by all authors. The first draft of the manuscript was written by Keisuke Yoshida, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Masahiro Toda.

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The authors declare that they have no conflict of interest.

Ethical approval

Approval was obtained from the ethics committee of Keio University School of Medicine. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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The patient consented to the submission of the case report to the journal.

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This article is part of the Topical Collection on Neurosurgery general

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Yoshida, K., Toda, M., Yamada, Y. et al. Sinking skin flap syndrome visualized by upright computed tomography. Acta Neurochir 162, 1825–1828 (2020). https://doi.org/10.1007/s00701-020-04459-7

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  • DOI: https://doi.org/10.1007/s00701-020-04459-7

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