Summary
Moyamoya disease is a progressive occlusive disease of the circle of Willis with prominent collateral arterial formation. We report on a 12-year-old girl with moyamoya disease presenting with transient ischemic attacks (TIAs). Surgical indirect revascularization was performed. The patient did not suffer further TIAs at 12 month follow-up. Pre and postoperative cerebral perfusion were studied in quantitative single photon emission computerized tomography (SPECT) and CT perfusion imaging. CT perfusion imaging demonstrated postoperatively increased cerebral blood flow as well as SPECT before and after revascularization. Furthermore, the area of decreased vascular reserve in SPECT with acetazolamide corresponded to areas of increased cerebral blood volume in CT perfusion imaging. CT perfusion imaging was equivalent to SPECT in accuracy, and superior in spatial resolution. CT perfusion imaging is likely to become more widely available as an easy-to-perform technique for assessing cerebral perfusion in a patients with moyamoya disease.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
JC Baron MG Bousser A Rey A Guillard D Comar P Castaigne (1981) ArticleTitleReversal of focal “misery-perfusion syndrome” by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography Stroke 12 454–459 Occurrence Handle6976022 Occurrence Handle1:STN:280:Bi2D1crmtlQ%3D
DS DeWitt PP Fatouros AO Wist LM Stewart HA Kontos JA Hall PR Kishore RL Keenan A Marmarou (1989) ArticleTitleStable xenon versus radiolabeled microsphere cerebral blood flow measurements in baboons. Stroke 20 1716–1723 Occurrence Handle2512692 Occurrence Handle1:STN:280:By%2BD1crislQ%3D
JD Eastwood MJ Alexander JR Petrella JM Provenzale (2002) ArticleTitleDynamic CT perfusion imaging with acetazolamide challenge for the preprocedural evaluation of a patient with symptomatic middle cerebral artery occlusive disease. AJNR Am J Neuroradiol 23 285–287 Occurrence Handle11847056
M Fukui (1997) ArticleTitleCurrent state of study on moyamoya disease in Japan. Surg Neurol 47 138–143 Occurrence Handle9040816 Occurrence Handle1:STN:280:ByiC1Mzit1A%3D
H Hoshi T Ohnishi S Jinnouchi S Futami S Nagamachi T Kodama K Watanabe T Ueda S Wakisaka (1994) ArticleTitleCerebral blood flow study in patients with moyamoya disease evaluated by IMP SPECT. J Nucl Med 35 44–50 Occurrence Handle8271059 Occurrence Handle1:STN:280:ByuD1MnhsFw%3D
K Ikezaki T Matsushima Y Kuwabara SO Suzuki T Nomura M Fukui (1994) ArticleTitleCerebral circulation and oxygen metabolism in childhood moyamoya disease: a perioperative positron emission tomography study. J Neurosurg 81 843–850 Occurrence Handle7965114 Occurrence Handle1:STN:280:ByqD2MvktlI%3D
SK Kim KC Wang CW Oh IO Kim DS Lee IC Song BK Cho (2003) ArticleTitleEvaluation of cerebral hemodynamics with perfusion MRI in childhood moyamoya disease. Pediatr Neurosurg 38 68–75 Occurrence Handle12566838 Occurrence Handle10.1159/000068050
M Koenig E Klotz B Luka DJ Venderink JF Spittler L Heuser (1998) ArticleTitlePerfusion CT of the brain: diagnostic approach for early detection of ischemic stroke. Radiology 209 85–93 Occurrence Handle9769817 Occurrence Handle1:STN:280:DyaK1cvktF2msQ%3D%3D
DE Kuhl JR Barrio SC Huang C Selin RF Ackermann JL Lear JL Wu TH Lin ME Phelps (1982) ArticleTitleQuantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography. J Nucl Med 23 196–203 Occurrence Handle6801219 Occurrence Handle1:STN:280:Bi2C2cvotFI%3D
Y Kuwabara Y Ichiya M Otsuka T Tahara R Gunasekera K Hasuo K Masuda T Matsushima M Fukui (1990) ArticleTitleCerebral hemodynamic change in the child and the adult with moyamoya disease. Stroke 21 272–277 Occurrence Handle2305403 Occurrence Handle1:STN:280:By%2BC283ns10%3D
RE Latchaw H Yonas SL Pentheny D Gur (1987) ArticleTitleAdverse reactions to xenon-enhanced CT cerebral blood flow determination. Radiology 163 251–254 Occurrence Handle3823444 Occurrence Handle1:STN:280:BiiC2cjpvFw%3D
T Matsushima S Fujiwara S Nagata K Fujii M Fukui K Kitamura K Hasuo (1989) ArticleTitleSurgical treatment for paediatric patients with moyamoya disease by indirect revascularization procedures (EDAS, EMS, EMAS). Acta Neurochir (Wien) 98 135–140 Occurrence Handle10.1007/BF01407339 Occurrence Handle1:STN:280:BiaA3c%2FjvVQ%3D
DJ McAuley K Poskitt P Steinbok (2004) ArticleTitlePredicting stroke risk in pediatric moyamoya disease with xenon-enhanced computed tomography. Neurosurgery 55 327–332 Occurrence Handle15271238
K Mizoi T Kayama T Yoshimoto Y Nagamine (1996) ArticleTitleIndirect revascularization for moyamoya disease: is there a beneficial effect for adult patients? Surg Neurol 45 541–548 Occurrence Handle8638240 Occurrence Handle1:STN:280:BymB38vpvFE%3D
Sakamoto S, Eguchi K, Kiura Y, Arita K, Kurisu K (in press) CT perfusion imaging in the syndrome of the sinking skin flap before and after cranioplasty. Clin Neurol Neurosurg
J Suzuki A Takaku (1969) ArticleTitleCerebrovascular “moyamoya” disease. Disease showing abnormal net-like vessels in base of brain. Arch Neurol 20 288–299 Occurrence Handle5775283 Occurrence Handle1:STN:280:CCaC3sbhvFY%3D
Y Suzuki M Negoro M Shibuya J Yoshida T Negoro K Watanabe (1997) ArticleTitleSurgical treatment for pediatric moyamoya disease: use of the superficial temporal artery for both areas supplied by the anterior and middle cerebral arteries. Neurosurgery 40 324–329 Occurrence Handle9007865 Occurrence Handle10.1097/00006123-199702000-00017 Occurrence Handle1:STN:280:ByiC28%2Fjs1E%3D
H Touho J Karasawa H Ohnishi (1996) ArticleTitlePreoperative and postoperative evaluation of cerebral perfusion and vasodilatory capacity with 99 mTc-HMPAO SPECT and acetazolamide in childhood Moyamoya disease. Stroke 27 282–289 Occurrence Handle8571424 Occurrence Handle1:CAS:528:DyaK28XhsV2lurg%3D
S Vorstrup B Brun NA Lassen (1986) ArticleTitleEvaluation of the cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery. Stroke 17 1291–1298 Occurrence Handle3492787 Occurrence Handle1:STN:280:BiiC387ivFA%3D
M Wintermark JP Thiran P Maeder P Schnyder R Meuli (2001) ArticleTitleSimultaneous measurement of regional cerebral blood flow by perfusion CT and stable xenon CT: a validation study. AJNR Am J Neuroradiol 22 905–914 Occurrence Handle11337336 Occurrence Handle1:STN:280:DC%2BD3MzotlGrtw%3D%3D
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sakamoto, S., Ohba, S., Shibukawa, M. et al. CT perfusion imaging for childhood moyamoya disease before and after surgical revascularization. Acta Neurochir (Wien) 148, 77–81 (2006). https://doi.org/10.1007/s00701-005-0634-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00701-005-0634-z