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A disposable electrochemical sensor based on electrospinning of molecularly imprinted nanohybrid films for highly sensitive determination of the organotin acaricide cyhexatin

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Abstract

Nanofibrous polyporous membranes imprinted with cyhexatin (CYT) were formed via the ordered distribution of the imprints in electrospun nanofibers. The MIPs have a high mass transfer rate and enhanced adsorption capacity. In addition, a printed carbon electrode with enhanced sensitivity was developed via electrochemical fabrication of reduced graphene oxide (rGO) and gold nanoparticles (AuNPs). The molecularly imprinted sensor exhibits excellent selectivity and sensitivity for CYT. The structure and morphology of the nanohybrid films were characterized by using scanning electron microscopy, atomic force microscopy and chronoamperometry. The sensing performances were evaluated by cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy by using hexacyanoferrate(IV) as an electrochemical probe. The electrode, best operated at a working potential of around 0.16 V (vs. Ag/AgCl), has a linear response in the 1–800 ng mL−1 CYT concentration range and a detection limit of 0.17 ng mL−1 (at S/N = 3). The sensor demonstrated satisfactory recoveries when applied to the determination of CYT in spiked pear samples.

Schematic presentation of the electrochemical sensor for detection of CYT.

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Acknowledgements

The authors acknowledge the funding from the National Natural Science Foundation of China (Contact No31471654, 31772071), and China Agriculture Research System (NoCARS-05-05A-03).

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Authors and Affiliations

  1. Key Laboratory of Agro-product Quality and Food Safety, Ministry of Agriculture, Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing, 100081, People’s Republic of China

    Chao Zhang, Yahui He, Yongxin She, Sihui Hong, Jun Ma, Miao Wang, Zhen Cao & Jing Wang

  2. School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, People’s Republic of China

    Chao Zhang, Fengnian Zhao, Jianfeng Ping & Yibin Ying

  3. College of Life Sciences and Engineering, Hebei University of Engineering, Handan, 056021, People’s Republic of China

    Tengfei Li

  4. Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt

    A. M. Abd EI-Aty

  5. Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240, Erzurum, Turkey

    A. M. Abd EI-Aty

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  1. Chao Zhang
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  2. Fengnian Zhao
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  13. Jing Wang
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Correspondence to Yongxin She or Jing Wang.

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Zhang, C., Zhao, F., He, Y. et al. A disposable electrochemical sensor based on electrospinning of molecularly imprinted nanohybrid films for highly sensitive determination of the organotin acaricide cyhexatin. Microchim Acta 186, 504 (2019). https://doi.org/10.1007/s00604-019-3631-2

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