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Electrochemical sensing of L-ascorbic acid by using a glassy carbon electrode modified with a molybdophosphate film

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Abstract

Electrochemical sensing of L-ascorbic acid (AA) is reported based on the use of a redox-active molybdophosphate film on a glassy carbon electrode (GCE). Molybdophosphate is formed by reacting hydroxyapatite nanoparticles with sodium molybdate. The modified GCE can be utilized for detection of AA, typically at a working potential of 0.4 V (vs. Ag/AgCl). The GCE has a decreased overpotential and enhanced sensitivity (219 μA·mM−1·cm−2). Response is linear in the 1 μM to 1.5 mM AA concentration range, and the limit of detection is 4 nM. The selectivity of this sensor makes it a useful tool for accurate determination of AA in practical samples as shown for a vitamin C tablet and for spiked beverages.

An electrochemical sensing platform is reported that is based on the use of a redox-active molybdophosphate film that was formed via reacting hydroxyapatite nanoparticles (HAP-NPs) with sodium molybdate. Graphical abstract contains poor quality of text inside the artwork. Please do not re-use the file that we have rejected or attempt to increase its resolution and re-save. It is originally poor, therefore, increasing the resolution will not solve the quality problem. We suggest that you provide us the original format. We prefer replacement figures containing vector/editable objects rather than embedded images. Preferred file formats are eps, ai, tiff and pdf.We have uploaded the graphical abstract as PDF format

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Acknowledgments

The authors thank the support of this work by the National Natural Science Foundation of China (No. 21575165).

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Authors and Affiliations

  1. Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China

    Shuping Liu, Xingxing Jiang & Minghui Yang

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  1. Shuping Liu
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  2. Xingxing Jiang
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  3. Minghui Yang
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Correspondence to Minghui Yang.

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Liu, S., Jiang, X. & Yang, M. Electrochemical sensing of L-ascorbic acid by using a glassy carbon electrode modified with a molybdophosphate film. Microchim Acta 186, 445 (2019). https://doi.org/10.1007/s00604-019-3562-y

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