Abstract
A 50-year-old woman was diagnosed as having stage IV breast cancer with bilateral supraclavicular lymph node metastasis resistant to CAF therapy. She received immunotherapy using autologous tumor lysate-pulsed dendritic cells (DCs). Four cycles of DC injection into the right supraclavicular lymph nodes resulted in regression of bilateral supraclavicular lymphogenous metastasis. Histological studies revealed an accumulation of CD45+ T lymphcytes in the regressive lymph nodes. This case suggests that immunotherapy with DCs may be a safe and promising approach for the treatment of advanced breast cancer.
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Received: July 27, 2000 / Accepted: January 9, 2001
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Kobayashi, T., Shinohara, H., Toyoda, M. et al. Regression of Lymph Node Metastases by Immunotherapy Using Autologous Breast Tumor-Lysate Pulsed Dendritic Cells: Report of a Case. Surg Today 31, 513–516 (2001). https://doi.org/10.1007/s005950170112
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DOI: https://doi.org/10.1007/s005950170112