Abstract
We report a case of nonfunctioning endocrine tumor of the pancreas with extrapancreatic growth and cyst formation. A 48-year-old woman was admitted to our hospital with an upper abdominal mass, which was detected during a routine medical checkup. The preoperative diagnosis was a solid cystic tumor of the pancreas. The tumor, which measured about 7 cm in diameter, arose from the head of the pancreas and had a thin stalk, measuring about 1 cm in diameter. The histopathological diagnosis was a malignant nonfunctioning endocrine tumor of the pancreas. Cyst formation occurred in 67% of the reported cases with extrapancreatic growth in Japan. It is speculated that the cyst formation in this disease is related to the large size of the tumor and to the extrapancreatic growth.
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Zeki S, Horie Y, Miura S, Akiba Y, Higuchi H, Hibi N, Oda M, Ishii H, Tsuchiya M, Shimazu M, Kitajima M, Matsuoka K, Sugiura H (1996) A case study of nonfunctioning islet cell tumor in patient with splenic tumor and increased AFP (in Japanese). Nippon Syokakibyo Gakkai Zasshi (Jpn J Gastroenterol) 93:382–387
Takashima N, Fukuda K, Yoshimura T, Miyoshi K, Moriwaki S (1977) Large non-functioning islet cell tumor of the pancreas; a case report (in Japanese). Rinsho Geka (J Clin Surg) 32:125–128
Yonemura Y, Miwa K, Koyama H, Miyazaki I, Nakanishi I, Matsubara H, Takashima T (1981) A case of non-functioning islet cell tumor, with extrapancreatic growth (in Japanese). Saishin Igaku 36:601–610
Yamaguchi G, Kawahara T, Maruyama N, Mototsugu J, Ninomiya H, Nagata H, Sakai K, Isomura T, Tanigawa H (1981) A case of giant nonfunctioning islet cell tumor (in Japanese). Rinsyo to Kenkyu 58:1506–1509
Okuno M, Sakaguchi S, Nagayama M, Yamashita T, Sakazaki S, Yoshikawa K, Taruya E, Fukamizu A, Ueyama K (1984) Nonfunctioning islet cell carcinoma presenting bleeding gastric varices and splenomegaly. Jpn J Surg 14:244–247
Onodera H, Oikawa M, Abe M, Chida N, Kimura T, Okabe N, Oikawa S, Goto Y, Sugawara N (1985) A case of islet cell tumor (in Japanese with English abstract). Rinsyo Hoshasen 30:621–624
Maeda K, Nishino H, Ikehara T, Kitoh H, Togoh K, Okuno M, Umeyama K (1990) A case of non-functioning islet cell carcinoma (in Japanese with English abstract). Suizo (J Jpn Pancr Soc) 5:516–521
Amano M, Mori H, Matsukawa S, Maeda J, Miyata A, Hayashida M, Irie J, Tomioka T (1991) A case report of nonfunctioning islet cell tumor with extrapancreatic growth (in Japanese with English abstract). Nippon Syokakigeka Gakkai Zasshi (Jpn J Gastroenterol Surg) 24:2452–2456
Nishihara K, Shinagawa Y, Shiragami T, Tominaga H, Kawamura A, Hamanaka Y, Murakami T, Suzuki T (1990) A case report of multiple asymptomatic pancreatic endocrine tumors arising in the extrapancreatic tissues (in Japanese with English abstract). Nippon Rinsho Geka Gakkai Zasshi (J Jpn Soc Clin Surg) 51:2257–2262
Waku T, Uetsuka H, Watanabe N, Mori T, Shiiki S, Nakai H, Orita Y, Harafuji I, Yoshino T (1997) A case of malignant asymptomatic pancreatic endocarcinoma with extrapancreatic growth (in Japanese with English abstract). Nippon Syokakigeka Gakkai Zasshi (Jpn J Gastroenterol Surg) 30:1942–1946
Mitani M, Kataoka M, Kuwabara Y, Taniwaki S, Kureyama Y, Kasugai T, Mitsui T, Kawamura H, Iwata H, Sakagami M, Kashima T, Sato A, Masaoka A, Tsuchiya T (1992) Investigation about preoperative diagnostic imagings of pancreatic islet cell tumors (in Japanese with English abstract). Nippon Rinsho Geka Gakkai Zasshi (J Jpn Soc Clin Surg) 53:685–694
Buetow PC, Parrino TV, Buck JL, Pantongrag-Brown L, Ros PR, Dachman AH, Cruess DF (1995) Islet cell tumors of the pancreas: pathologic-imaging correlation among size, necrosis and cysts, calcification, malignant behavior, and functional status. AJR 165:1175–1179
Tomioka T, Miyagi N, Nakata T, Miyata A, Amano M, Mori H, Hayashida M, Saeki S (1983) A case report of nonfunctioning islet cell tumor — a review of Japanese literature (in Japanese). Nippon Syokakigeka Gakkai Zasshi (Jpn J Gastroenterol Surg) 16:1389–1394
Kondo S, Nimura Y, Hayakawa N, Kamiya J, Shionoya S (1987) Imaging diagnosis of solid and cystic tumor of the pancreas (in Japanese). Hukubu Gazosindan 7:419–425
Takeshita K, Furui S, Yamauchi T, Irie T, Tsuchiya K, Kusano S, Ohtomo K (1994) Cystic islet cell tumors: Radioloyic findings in three cases. Abdom Imaging 19:225–228
Sohaib SAA, Reznek RH, Healy JC, Besser GM (1998) Cystic islet cell tumors of the pancreas. AJR 170:217
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Kato, K., Kondo, S., Ambo, Y. et al. Nonfunctioning endocrine tumor of the pancreas with extrapancreatic growth and cyst formation: Report of a case. Surg Today 30, 651–654 (2000). https://doi.org/10.1007/s005950070107
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DOI: https://doi.org/10.1007/s005950070107