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Impact of frailty on early and mid-term outcomes of hybrid aortic arch repair

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Abstract

Purpose

The purpose of this study was to investigate the impact of frailty on the clinical outcomes of hybrid aortic arch repair with debranching of the supra-aortic arteries.

Methods

Consecutive patients ≥ 75 years old who underwent hybrid aortic arch repair from January 2010 to December 2019 were retrospectively analyzed. Using the Canadian Study of Health and Aging (CSHA) scale, all patients with a CSHA scale score > 4 were defined as frail. The frail patients (FP) group and the non-frail patients (NFP) group were compared regarding the early and mid-term outcomes of hybrid aortic arch repair.

Results

A total of 84 patients were included. The early postoperative results were not markedly different between the groups, except that the rate of transfer to a rehabilitation hospital was higher in the FP group than in the NFP group. The survival at 5 years was significantly lower in the FP group at 43.0% than in the NFP group at 67.7% (P = 0.015). However, the freedom from aorta-related death was not significantly different between the two groups.

Conclusion

Frailty did not affect the short-term outcomes of hybrid aortic arch repair; however, the mid-term outcomes, including the survival, of the frail patients were significantly worse than those of the non-frail patients, mostly because of non-aorta-related causes.

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Acknowledgements

This work was supported, in part, by JSPS KAKENHI Grant number 16K10659

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Authors and Affiliations

  1. Division of Cardiovascular Surgery, Tottori University School of Medicine, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan

    Yuichiro Kishimoto, Yasushi Yoshikawa, Kenichi Morimoto, Takeshi Onohara, Hiromu Horie, Kunitaka Kumagai, Rikuto Nii & Motonobu Nishimura

Authors
  1. Yuichiro Kishimoto
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  2. Yasushi Yoshikawa
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  3. Kenichi Morimoto
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  4. Takeshi Onohara
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  5. Hiromu Horie
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  6. Kunitaka Kumagai
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  7. Rikuto Nii
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  8. Motonobu Nishimura
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Correspondence to Yasushi Yoshikawa.

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Kishimoto, Y., Yoshikawa, Y., Morimoto, K. et al. Impact of frailty on early and mid-term outcomes of hybrid aortic arch repair. Surg Today 52, 1194–1201 (2022). https://doi.org/10.1007/s00595-021-02443-x

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  • DOI: https://doi.org/10.1007/s00595-021-02443-x

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