Skip to main content
SpringerLink
Log in

A combination procedure with thrombolytic therapy and balloon dilatation for portal vein thrombus enables the successful performance of antiviral therapy after a living-donor liver transplantation: Report of a case

  • Case Report
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

This report presents a case of portal vein thrombosis possibly caused by anastomotic stricture after livingdonor liver transplantation. The patient underwent systemic thrombolytic therapy with tissue plasminogen activator and subsequent balloon dilatation of the stenotic lesion, and both were successful. These procedures allowed the patient to receive antiviral therapy to improve the pancytopenia, leading to a sustained virological response.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cavallari A, Vivarelli M, Bellusci R, Jovine E, Mazziotti A, Rossi C. Treatment of vascular complications following liver transplantation: multidisciplinary approach. Hepatogastroenterology 2001;48:179–183.

    CAS  PubMed  Google Scholar 

  2. Settmacher U, Nussler NC, Glanemann M, Haase R, Heise M, Bechstein WO, et al. Venous complications after orthotopic liver transplantation. Clin Transplant 2000;14:235–241.

    Article  CAS  PubMed  Google Scholar 

  3. Kyoden Y, Tamura S, Sugawara Y, Matsui Y, Togashi J, Kaneko J, et al. Portal vein complications after adult-to-adult living donor liver transplantation. Transpl Int 2008;21:1136–1144.

    Article  PubMed  Google Scholar 

  4. Ueda M, Oike F, Kasahara M, Ogura Y, Ogawa K, Haga H, et al. Portal vein complications in pediatric living donor liver transplantation using left-side grafts. Am J Transplant 2008;8:2097–2105.

    Article  CAS  PubMed  Google Scholar 

  5. Ko GY, Sung KB, Yoon HK, Lee S. Early posttransplantation portal vein stenosis following living donor liver transplantation: percutaneous transhepatic primary stent placement. Liver Transpl 2007;13:530–536.

    Article  PubMed  Google Scholar 

  6. Shibata T, Itoh K, Maetani Y, Shibata T, Togashi K, Tanaka K. Percutaneous transhepatic balloon dilation of portal venous stenosis in patients with living donor liver transplantation. Radiology 2005;235:1078–1083.

    Article  PubMed  Google Scholar 

  7. Eguchi S, Takatsuki M, Hidaka M, Tajima Y, Kanematsu T. Evolution of living donor liver transplantation over 10 years: experience of a single center. Surg Today 2008;38:795–800.

    Article  PubMed  Google Scholar 

  8. Lee SG, Hwang S, Kim KH, Ahn CS, Moon DB, Ha TY, et al. Toward 300 liver transplants a year. Surg Today 2009;39:367–373.

    Article  CAS  PubMed  Google Scholar 

  9. Miyazaki K, Takatsuki M, Eguchi S, Hidaka M, Yamanouchi K, Hamasaki K, et al. Living donor liver transplantation for a patient with huge portal venous aneurysm. Liver Transplant 2007;14:1225–1226.

    Google Scholar 

  10. Takatsuki M, Chen CL, Chen YS, Huang TL. Systemic thrombolytic therapy for late onset portal vein thrombosis after livingdonor liver transplantation. Transplantation 2004;77:1014–1018.

    CAS  PubMed  Google Scholar 

  11. Uflacker R. Applications of percutaneous mechanical thrombectomy in transjugular intrahepatic portosystemic shunt and portal vein thrombosis. Tech Vasc Interv Radiol 2003;6:59–69.

    Article  PubMed  Google Scholar 

  12. Henao EA, Bohannon WT, Silva MB Jr. Treatment of portal venous thrombosis with selective superior mesenteric artery infusion of recombinant tissue plasminogen activator. J Vasc Surg 2003;38:1411–1415.

    Article  CAS  PubMed  Google Scholar 

  13. Gluckelberger O, Bechstein WO, Langrehr JM, Kratschmer B, Loeffel J, Settmacher U, et al. Successful recanalization of late portal vein thrombosis after liver transplantation using systemic low-dose recombinant tissue plasminogen activator. Transpl Int 1999;12:273–277.

    Article  Google Scholar 

  14. Vignali C, Cioni R, Petruzzi P, Cicorelli A, Bargellini I, Perri M, et al. Role of interventional radiology in the management of vascular complications after liver transplantation. Transplant Proc 2004;36:552–554.

    Article  CAS  PubMed  Google Scholar 

  15. Ichikawa T, Nakao K, Hamasaki K, Honda T, Shibata H, Akahoshi M, et al. Clearance of hepatitis C virus after living-donor liver transplantation in spite of residual viremia on end date of interferon therapy before transplantation. World J Gastroenterol 2007;13:4149–4151.

    CAS  PubMed  Google Scholar 

  16. Eguchi S, Takatsuki M, Soyama A, Hidaka M, Tokai H, Hamasaki K, et al. Intentional conversion from tacrolimus to cyclosporine for HCV-positive patients on preemptive interferon therapy after living donor liver transplantation. Ann Transplant 2007;12:11–15.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan

    Koji Hamasaki, Susumu Eguchi, Mitsuhisa Takatsuki, Kensuke Miyazaki, Akihiko Soyama, Masaaki Hidaka, Kosho Yamanouchi, Yoshitsugu Tajima & Takashi Kanematsu

Authors
  1. Koji Hamasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Susumu Eguchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mitsuhisa Takatsuki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kensuke Miyazaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Akihiko Soyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Masaaki Hidaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Kosho Yamanouchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Yoshitsugu Tajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Takashi Kanematsu
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hamasaki, K., Eguchi, S., Takatsuki, M. et al. A combination procedure with thrombolytic therapy and balloon dilatation for portal vein thrombus enables the successful performance of antiviral therapy after a living-donor liver transplantation: Report of a case. Surg Today 40, 986–989 (2010). https://doi.org/10.1007/s00595-009-4159-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-009-4159-6

Key words

Search

Navigation