Abstract
Epithelioid hemangioendothelioma (EH) of the liver is a rare tumor, generally considered to have low-grade malignancy. Little is known about its clinical behavior and the therapeutic strategy is not established. We report the case of a 36-year-old woman who underwent living donor liver transplantation for EH with splenic metastases and died of recurrence 8 months later. To determine if transplantation improves the prognosis of patients with EH, we must re-evaluate its indications.
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References
KG Ishak IA Sesterhenn MD Goodman L Rabin FW Stromeyer (1984) ArticleTitleEpithelioid hemangioendothelioma of the liver: a clinicopathologic and follow-up study of 32 cases Hum Pathol 15 839–52 Occurrence Handle6088383 Occurrence Handle1:STN:280:DyaL2c3oslCqsQ%3D%3D
JM Läufer A Zimmermann L Krähenbühl J Triller HU Baer (1996) ArticleTitleEpithelioid hemangioendothelioma of the liver: a rare hepatic tumor Cancer 78 2318–27 Occurrence Handle10.1002/(SICI)1097-0142(19961201)78:11<2318::AID-CNCR8>3.0.CO;2-I
HR Makhlouf KG Ishak ZD Goodman (1999) ArticleTitleEpithelioid hemangioendothelioma of the liver: a clinicopathologic study of 137 cases Cancer 85 562–82 Occurrence Handle10091730 Occurrence Handle1:STN:280:DyaK1M7ptVWmsw%3D%3D Occurrence Handle10.1002/(SICI)1097-0142(19990201)85:3<562::AID-CNCR7>3.0.CO;2-T
MB Kelleher S Iwatsuki DG Sheahan (1989) ArticleTitleEpithelioid hemangioendothelioma of liver: clinicopathological correlation of 10 cases treated by orthotopic liver transplantation Am J Surg Pathol 13 999–1008 Occurrence Handle2596622 Occurrence Handle1:STN:280:DyaK3c%2FoslWrtw%3D%3D Occurrence Handle10.1097/00000478-198912000-00001
K Uchimura M Nakamuta M Osoegawa S Takeaki H Nishi H Iwamoto et al. (2001) ArticleTitleHepatic epithelioid hemangioendothelioma J Clin Gastroenterol 32 431–4 Occurrence Handle11319317 Occurrence Handle1:STN:280:DC%2BD3M3jtFSksA%3D%3D Occurrence Handle10.1097/00004836-200105000-00015
d'Annibale M, Iovanello P, Carlini P, Del Nonno F, Sciarretta F, Rossi M et al. Epithelioid hemangioendothelioma of the liver: case report and review of the literature. Transpl Proc 2002;34:1248–51
JY Scoazec P Lamy C Degott M Reynes G Feldmann H Bismuth et al. (1988) ArticleTitleEpithelioid hemangioendothelioma of the liver: diagnostic features and role of liver transplantation Gastroenterology 94 1447–53 Occurrence Handle3282968 Occurrence Handle1:STN:280:DyaL1c7ps1OltQ%3D%3D
IR Marino S Todo AG Tzakis G Klintmalm M Kelleher S Iwatsuki et al. (1988) ArticleTitleTreatment of hepatic epithelioid hemangioendothelioma with liver transplantation Cancer 62 2079–84 Occurrence Handle3052779 Occurrence Handle1:STN:280:DyaL1M%2FivVSrsw%3D%3D Occurrence Handle10.1002/1097-0142(19881115)62:10<2079::AID-CNCR2820621002>3.0.CO;2-J
CF Hung LB Jeng WC Lee DY Lin PPC Tan MF Chen (1998) ArticleTitleLiver transplantation for epithelioid hemangioendothelioma Transpl Proc 30 3307–9 Occurrence Handle1:STN:280:DyaK1M%2FlsFynsw%3D%3D Occurrence Handle10.1016/S0041-1345(98)01041-0
M Ben-Haim S Roayaie MQ Ye SN Thung S Emre TA Fishbein et al. (1999) ArticleTitleHepatic epithelioid hemangioendothelioma: resection or transplantation, which and when? Liver Transpl Surg 5 526–31 Occurrence Handle10545542 Occurrence Handle1:STN:280:DC%2BD3c%2FhsFejtA%3D%3D Occurrence Handle10.1002/lt.500050612
LK Kayler RM Merion JD Arenas JC Magee DA Campbell SM Rudich et al. (2002) ArticleTitleEpithelioid hemangioendothelioma of the liver disseminated to the peritoneum treated with liver transplantation and interferon alpha-2B Transplantation 74 128–30 Occurrence Handle12134111 Occurrence Handle10.1097/00007890-200207150-00022
JP Lerut G Orlando C Sempoux O Ciccarelli BE Van Beers E Danse et al. (2004) ArticleTitleHepatic hemangioendothelioma in adults: excellent outcome following liver transplantation Transpl Int 17 202–7 Occurrence Handle15114438 Occurrence Handle10.1111/j.1432-2277.2004.tb00429.x
J Van de Stadt M Gelin M Adler JP Lambilliotte (1989) ArticleTitleEpithelioid hemangioendothelioma and liver transplantation Gastroenterology 96 275–6 Occurrence Handle2642441 Occurrence Handle1:STN:280:DyaL1M%2FnvV2jtA%3D%3D
ND Simpson AM Ahmed PW Simpson JA Parker EB Keeffe A Ahmed (2003) ArticleTitleLiving donor liver transplantation in a patient with hepatic epithelioid hemangioendothelioma J Clin Gastroenterol 37 349–50 Occurrence Handle14506396 Occurrence Handle10.1097/00004836-200310000-00017
AJ Demetris M Minervini RB Raikow RG Lee (1997) ArticleTitleHepatic epithelioid hemangioendothelioma: biological questions based on pattern of recurrence in an allograft and tumor immunophenotype Am J Surg Pathol 21 263–70 Occurrence Handle9060595 Occurrence Handle1:STN:280:DyaK2s3htl2jtA%3D%3D Occurrence Handle10.1097/00000478-199703000-00001
SD St Peter AA Moss EA Huettl KO Leslie DC Mulligan (2003) ArticleTitleChemoembolization followed by orthotopic liver transplantation for epithelioid hemangioendothelioma Clin Transpl 17 549–53 Occurrence Handle10.1046/j.1399-0012.2003.00055.x
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Hasegawa, K., Sugawara, Y., Ikeda, M. et al. Living Donor Liver Transplantation for Epithelioid Hemangioendothelioma: Report of a Case. Surg Today 36, 1024–1027 (2006). https://doi.org/10.1007/s00595-006-3292-8
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DOI: https://doi.org/10.1007/s00595-006-3292-8