Abstract
Introduction
We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features.
Case report
A 26-year-old female presented to our hospital because of difficulty in walking due to progressive paresis. Magnetic resonance imaging of the thoracic spinal cord showed multiple spinal cord tumors. Surgical resection of these tumors was performed and a different histological diagnosis including World Health Organization Grade III anaplastic ependymoma and Grade II ependymoma was obtained using the resected specimen. Additional radiotherapy and chemotherapy were also performed, and a successful outcome has been maintained for at least 3 years after surgery.
Conclusion
Surgical resections and subsequent radiotherapy and chemotherapy for cases with multiple intradural-extramedullary ependymomas can result in a good postoperative course.
References
Duffau H, Gazzaz M, Kujas M et al (2000) Primary intradural extramedullary ependymoma: case report and review of the literature. Spine 25:1993–1995
Fourney DR, Siadati A, Bruner JM et al (2004) Giant cell ependymoma of the spinal cord. Case report and review of the literature. J Neurosurg Spine 100:75–79
Iunes EA, Stávale JN, de Cássia Caldas Pessoa R et al (2011) Multifocal intradural extramedullary ependymoma. Case report. J Neurosurg Spine 14:65–70
Landril F, Ajler P, Tedesco N et al (2012) Multicentric extramedullary myxopapillary ependymomas: two case reports and literature review. Surg Neurol Int 3:102
Vural M, Arslantas A, Ciftci E et al (2010) Multiple intradural-extramedullary ependymomas: proven dissemination by genetic analysis. J Neurosurg Spine 12:467–473
Cerase A, Venturi C, Oliveri G et al (2006) Intradural extramedullary spinal anaplastic ependymoma. Case illustration. J Neurosurg Spine 5:476
Graca J, Gultasli N, D’Haene N et al (2006) Cystic extramedullary ependymoma. Am J Neuroradiol 27:818–821
Robles SG, Saldana C, Boto GR et al (2005) Intradural extramedullary spinal ependymoma: a benign pathology? Spine (Phila Pa 1976) 30:E251–E254
Schuurmans M, Vanneste JA, Verstegen MJ et al (2006) Spinal extramedullary anaplastic ependymoma with spinal and intracranial metastases. J Neurooncol 79:57
Pomeraniec IJ, Dallapiazza RF, Sumner HM et al (2015) Anaplastic extramedullary cervical ependymoma with leptomeningeal metastasis. J Clin Neurosci 22:1871–1876
Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996
Gramatzki D, Roth P, Felsberg J et al (2016) Chemotherapy for intracranial ependymoma in adults. BMC Cancer 16:287
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Honda, A., Iizuka, Y., Hirato, J. et al. Multiple intradural-extramedullary spinal ependymomas including tumors with different histological features. Eur Spine J 26 (Suppl 1), 222–224 (2017). https://doi.org/10.1007/s00586-017-5055-1
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DOI: https://doi.org/10.1007/s00586-017-5055-1