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Parasitological studies and hematological alterations among infected patients with chronic diarrhea

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Abstract

Chronic diarrhea is considered one of the leading causes of morbidity and mortality around the world, especially in developing nations. The current study explored the parasitological studies and hematologic alterations associated with gastroenteritis infection among patients with chronic diarrhea. A cross-sectional study was conducted on patients suffering from chronic diarrhea and matched the healthy control group. Complete blood count and serum iron profile (iron level, total iron-binding capacity (TIBC), and transferrin saturation) assayed. About 125 infected patients were suffering from watery diarrhea and were investigated for various intestinal parasitic pathogens during the period of the study. The prevalence of the most common enteric pathogens isolated were hookworms (41.6%), Ascaris (21.6%), and whipworm (36.8%). Hematological examination showed remarkable alterations in CBC and iron profile compared with those of healthy control subjects. The study participants infected with hookworms, Ascaris, and whipworms demonstrated vital alterations in hematological parameters that could be helpful for the diagnosis of chronic diarrhea that has a deleterious effect on morbidity and mortality in participants.

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Correspondence to Nabil Hasona.

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The authors declare no competing interests.

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All the participants provided informed consent for our study. Our study was carried out in accordance with the Helsinki Declaration, and institutional ethics committee approval was obtained from the College of Applied medical Science, Hail University, KSA.

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Hasona, N., Amer, O.H., Alouffi, S. et al. Parasitological studies and hematological alterations among infected patients with chronic diarrhea. Comp Clin Pathol 31, 317–321 (2022). https://doi.org/10.1007/s00580-022-03335-3

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  • DOI: https://doi.org/10.1007/s00580-022-03335-3

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