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Development of sensor-probe system with function of measuring flow and pressure for evaluating breathing property at airway in lungs

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Abstract

We propose a sensor-probe system for evaluating local airway resistance in the lungs. The system consists of a micro-machined thermal-flow sensor, based on the hot-wire airflow-meter principle, fabricated on a flexible substrate consisting of Cu foil and polyimide film and a commercially available Si pressure sensor. We inserted the system into a tube with a 5.0-mm inner diameter to evaluate its detection properties under a steady-flow of up to 6.0 L/m. The flow velocity vs. sensor output and pressure vs. tube length were successfully obtained. We then applied the system for reciprocating airflow measurement. A flow of 30 cc at 0.5 Hz generated with an artificial ventilator was used to imitate the breathing of a small animal, and we confirmed that the system successfully detected both flow and pressure change generated in the tube.

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Acknowledgements

This work was supported by JSPS KAKENHI Grant Number JP18K04912, Hiroshima City University Grant for Special Academic Research.

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Authors and Affiliations

  1. Department Biomedical Information Science, Hiroshima City University, Hiroshima, Japan

    Yuji Kawamoto, Yoshifumi Maeda, Yoshihiro Hasegawa & Mitsuhiro Shikida

  2. Department of Medical Technology, Nagoya University, Nagoya, Japan

    Miyoko Matsushima & Tsutomu Kawabe

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  1. Yuji Kawamoto
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  2. Yoshifumi Maeda
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  3. Yoshihiro Hasegawa
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  4. Miyoko Matsushima
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  5. Tsutomu Kawabe
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  6. Mitsuhiro Shikida
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Correspondence to Yoshihiro Hasegawa.

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Kawamoto, Y., Maeda, Y., Hasegawa, Y. et al. Development of sensor-probe system with function of measuring flow and pressure for evaluating breathing property at airway in lungs. Microsyst Technol 27, 3935–3942 (2021). https://doi.org/10.1007/s00542-020-05201-0

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  • DOI: https://doi.org/10.1007/s00542-020-05201-0

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