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Right ventricular and atrial functions in patients with nonischemic dilated cardiomyopathy

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Summary

Objective

The aim of this study was to assess the right ventricular and right atrial functions in patients with nonischemic dilated cardiomyopathy by novel echocardiographic measures.

Methods

In all, 40 patients with nonischemic dilated cardiomyopathy and 26 healthy subjects were consecutively included. Left ventricular, right ventricular, and right atrial functions were assessed by tissue Doppler imaging and two-dimensional speckle tracking echocardiography. Right ventricular systolic dysfunction was accepted moderated to severe when tissue Doppler peak systolic velocity of tricuspid lateral annulus was < 9 cm/s.

Results

In all, 18 of the 40 nonischemic dilated cardiomyopathy patients had peak systolic velocity of tricuspid lateral annulus < 9 cm/s and had significantly lower right ventricular free wall basal segment longitudinal strain, displacement, and right atrial functions assessed by speckle tracking echocardiography. Left ventricular tissue Doppler systolic velocity, global longitudinal and circumferential strain values were also lower in patients with moderated to severe right ventricular systolic dysfunction. Receiver operating characteristic analysis was preformed to assess the utility of right ventricular free wall basal segment longitudinal strain to predict right ventricular systolic dysfunction (peak systolic velocity < 9 cm/s). The cut off value for predicting right ventricular systolic dysfunction was − 20 % with a sensitivity of 72%  and specificity of 73%  (AUC: 0.793; p = 0.002; 95 % confidence interval: 0.645–0.941).

Conclusions

Right ventricular systolic function is impaired in nonischemic dilated cardiomyopathy patients. Two-dimensional speckle tracking echocardiography represents a promising noninvasive method to evaluate right ventricular and atrial function in this patient group.

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Authors and Affiliations

  1. Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey

    Kursat Tigen MD, Altug Cincin MD,  Beste Ozben MD, Murat Sunbul MD &  Yelda Basaran MD

  2. Department of Cardiology, Acibadem University Faculty of Medicine, Istanbul, Turkey

    Tansu Karaahmet MD

  3. Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey

    Cihan Dundar MD, Ahmet Guler MD & Emre Gurel MD

Authors
  1. Kursat Tigen MD
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  2. Tansu Karaahmet MD
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  3. Cihan Dundar MD
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  4. Altug Cincin MD
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  5. Beste Ozben MD
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  6. Ahmet Guler MD
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Correspondence to Murat Sunbul MD.

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Tigen, K., Karaahmet, T., Dundar, C. et al. Right ventricular and atrial functions in patients with nonischemic dilated cardiomyopathy. Wien Klin Wochenschr 127, 877–883 (2015). https://doi.org/10.1007/s00508-015-0852-1

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  • DOI: https://doi.org/10.1007/s00508-015-0852-1

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