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Laparoscopic gastrectomy and metastasectomy for stage IV gastric cancer

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A Correction to this article was published on 12 May 2020

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Abstract

Background

The standard recommended treatment of stage IV gastric cancer is palliative chemotherapy. The aim of this study is to evaluate the role of radical gastrectomy with metastasectomy in these patients, as well as to explore the feasibility and safety of a laparoscopic approach.

Methods

117 consecutive patients with pathologically proven Stage IV gastric cancer who underwent radical gastrectomy with metastasectomy were enrolled in this study. We evaluated short-term and long-term outcomes, comparing laparoscopic surgery with open surgery by propensity score matching.

Results

The 5-year overall survival rate (OSR) was 23.2% and the median survival time (MST) was 19.8 months. After propensity scoring matching, the 5-year OSR and MST of laparoscopy group was 23.4%, 17.9 months and in the open group, it was 25.0%, 22.8 months (p = 0.882). The complication rate was 5.6% in the laparoscopy group and 23.4% in the open group (p = 0.069). In multivariate analysis, adjuvant chemotherapy, chemotherapy cycle, and postoperative complication were independent prognostic factors of overall survival.

Conclusions

Radical gastrectomy with metastasectomy could have a potential role in stage IV gastric cancer. Laparoscopic gastrectomy with metastasectomy in selected stage IV gastric cancer patients is safe and feasible.

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Author notes

  1. Sa-Hong Min

    Present address: Chungnam National University Sejong Hospital, Daejeon, South Korea

Authors and Affiliations

  1. Department of Surgery, Seoul National University Bundang Hospital, 82, Gumi-ro 173 beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea

    Sa-Hong Min, Yongjoon Won, Kanghaeng Lee, Sang Il Youn, Guowei Kim, Young Suk Park, Sang-Hoon Ahn, Do Joong Park & Hyung-Ho Kim

  2. Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea

    Sang-Hoon Ahn, Do Joong Park & Hyung-Ho Kim

  3. University Surgical Cluster, National University Health System, Singapore, Singapore

    Guowei Kim

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  1. Sa-Hong Min
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Correspondence to Hyung-Ho Kim.

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Disclosure

Sa-Hong Min, YongjoonWon, Kanghaeng Lee, Sang Il Youn, Guowei Kim, Young Suk Park, Sang-Hoon Ahn, Do Joong Park, and Hyung-Ho Kim have no conflict of interest to disclose.

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This article was updated: Do Joong Park’s name was incorrect in the original article. It is correct as displayed here and above: Do Joong (given name) Park (family name).

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Min, SH., Won, Y., Lee, K. et al. Laparoscopic gastrectomy and metastasectomy for stage IV gastric cancer. Surg Endosc 35, 1879–1887 (2021). https://doi.org/10.1007/s00464-020-07592-7

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