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Surgical techniques to minimize shoulder pain after laparoscopic cholecystectomy. A systematic review

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Abstract

Background

Laparoscopic cholecystectomy (LC) is the treatment of choice for symptomatic cholecystolithiasis. Despite the many advantages over open surgery, many patients complain about referred pain to the shoulder during the postoperative course. The purpose of this review was to evaluate different intraoperative surgical methods to minimize shoulder pain (SP).

Methods

A search of the literature was conducted using PubMed, Excerpta Medica Database (EMBASE), and Cochrane database of systematic reviews. Eligibility criteria were: randomized clinical trials or meta-analysis evaluating intraoperative surgical methods applied to minimize incidence or severity of SP after LC. Only papers published in English were included. Data extracted were year of publication, number of participants and allocation, nonsignificant or significant effect on incidence or severity of SP.

Results

A total of 31 papers where included in the review. Seven, 8, and 12 papers investigated the effect of drains, abdominal wall lift (AWL), and low-pressure pneumoperitoneum respectively. Four papers investigated drain suction, active gas aspiration, low insufflation flow or N2O insufflation respectively. The interventions that overall showed a significant reduction on either the incidence or severity of SP were low-pressure pneumoperitoneum, low insufflation rate, and active gas aspiration.

Conclusions

Drainage and AWL are not recommended to reduce SP after LC. Low-pressure pneumoperitoneum with carbon dioxide is the best documented intraoperative surgical method to minimize both the incidence and severity of SP after LC.

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References

  1. Keus F, Gooszen HG, van Laarhoven CJ (2010) Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews. Cochrane Database Syst Rev 1:CD008318. doi:10.1002/14651858.CD008318

  2. Bisgaard T, Kehlet H, Rosenberg J (2001) Pain and convalescence after laparoscopic cholecystectomy. Eur J Surg 167:84–96

    Article  PubMed  CAS  Google Scholar 

  3. Jensen K, Kehlet H, Lund CM (2009) Postoperative recovery profile after elective abdominal hysterectomy: a prospective, observational study of a multimodal anaesthetic regime. Eur J Anaesthesiol 26:382–388

    Article  PubMed  CAS  Google Scholar 

  4. Paulson J, Mellinger J, Baguley W (2003) The use of intraperitoneal bupivacaine to decrease the length of stay in elective laparoscopic cholecystectomy patients. Am Surg 69:275–278

    PubMed  Google Scholar 

  5. Kandil TS, El Hefnawy E (2010) Shoulder pain following laparoscopic cholecystectomy: factors affecting the incidence and severity. J Laparoendosc Adv Surg Tech A 20:677–682

    Article  PubMed  Google Scholar 

  6. Sandhu T, Yamada S, Ariyakachon V, Chakrabandhu T, Chongruksut W, Ko-iam W (2009) Low-pressure pneumoperitoneum versus standard pneumoperitoneum in laparoscopic cholecystectomy, a prospective randomized clinical trial. Surg Endosc 23:1044–1047

    Article  PubMed  Google Scholar 

  7. Tsimoyiannis EC, Siakas P, Tassis A, Lekkas ET, Tzourou H, Kambili M (1998) Intraperitoneal normal saline infusion for postoperative pain after laparoscopic cholecystectomy. World J Surg 22:824–828

    Article  PubMed  CAS  Google Scholar 

  8. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700. doi:10.1136/bmj.b2700

  9. Kahokehr A, Sammour T, Shoshtari KZ, Taylor M, Hill AG (2011) Intraperitoneal local anesthetic improves recovery after colon resection: a double-blinded randomized controlled trial. Ann Surg 254:28–38

    Article  PubMed  Google Scholar 

  10. Kahokehr A, Sammour T, Soop M, Hill AG (2011) Intraperitoneal local anaesthetic in abdominal surgery—a systematic review. ANZ J Surg 81:237–245

    Article  PubMed  Google Scholar 

  11. Georgiou C, Demetriou N, Pallaris T, Theodosopoulos T, Katsouyanni K, Polymeneas G (2011) Is the routine use of drainage after elective laparoscopic cholecystectomy justified? A randomized trial. J Laparoendosc Adv Surg Tech A 21:119–123

    Article  PubMed  Google Scholar 

  12. Hawasli A, Brown E (1994) The effect of drains in laparoscopic cholecystectomy. J Laparoendosc Surg 4:393–398

    Article  PubMed  CAS  Google Scholar 

  13. Mrozowicz A, Rucinski P, Polkowski WP (2006) Routine drainage of the subhepatic area after laparoscopic cholecystectomy. Prospective, controlled study with random patient selection. Polski Przeglad Chirurgiczny 78:597–609

    Google Scholar 

  14. Mrsic V, Nesek-Adam V, Budinscak I, Smiljanic A, Cala Z, Rasic Z (1997) Effect of abdominal drainage on postoperative shoulder pain in laparoscopic cholecystectomy. Croat J Gastroenterol Hepatol 6:41–44

    Google Scholar 

  15. Nursal TZ, Yildirim S, Tarim A, Noyan T, Poyraz P, Tuna N, Haberal M (2003) Effect of drainage on postoperative nausea, vomiting, and pain after laparoscopic cholecystectomy. Langenbecks Arch Surg 388:95–100

    PubMed  Google Scholar 

  16. Gurusamy Kurinchi S, Samraj K, Mullerat P, Davidson Brian R (2007) Routine abdominal drainage for uncomplicated laparoscopic cholecystectomy. Cochrane Database Syst Rev. doi:10.1002/14651858.CD006004.pub3

    Google Scholar 

  17. Barczynski M, Herman RM (2003) A prospective randomized trial on comparison of low-pressure (LP) and standard-pressure (SP) pneumoperitoneum for laparoscopic cholecystectomy. Surg Endosc 17:533–538

    Article  PubMed  CAS  Google Scholar 

  18. Beqiri AI, Domi RQ, Sula HH, Zaimi EQ, Petrela EY (2012) The combination of infiltrative bupivacaine with low-pressure laparoscopy reduces postcholecystectomy pain. A prospective randomized controlled study. Saudi Med J 33:134–138

    PubMed  Google Scholar 

  19. Chok KS, Yuen WK, Lau H, Fan ST (2006) Prospective randomized trial on low-pressure versus standard-pressure pneumoperitoneum in outpatient laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech 16:383–386

    Article  PubMed  Google Scholar 

  20. Esmat ME, Elsebae MM, Nasr MM, Elsebaie SB (2006) Combined low pressure pneumoperitoneum and intraperitoneal infusion of normal saline for reducing shoulder tip pain following laparoscopic cholecystectomy. World J Surg 30:1969–1973

    Article  PubMed  Google Scholar 

  21. Ibraheim OA, Samarkandi AH, Alshehry H, Faden A, Farouk EO (2006) Lactate and acid base changes during laparoscopic cholecystectomy. Middle East J Anesthesiol 18:757–768

    PubMed  Google Scholar 

  22. Kanwer DB, Kaman L, Nedounsejiane M, Medhi B, Verma GR, Bala I (2009) Comparative study of low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy—a randomised controlled trial. Trop Gastroenterol 30:171–174

    PubMed  Google Scholar 

  23. Perrakis E, Vezakis A, Velimezis G, Savanis G, Deverakis S, Antoniades J, Sagkana E (2003) Randomized comparison between different insufflation pressures for laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech 13:245–249

    Article  PubMed  CAS  Google Scholar 

  24. Sarli L, Costi R, Sansebastiano G, Trivelli M, Roncoroni L (2000) Prospective randomized trial of low-pressure pneumoperitoneum for reduction of shoulder-tip pain following laparoscopy. Br J Surg 87:1161–1165

    Article  PubMed  CAS  Google Scholar 

  25. Yasir M, Mehta KS, Banday VH, Aiman A, Masood I, Iqbal B (2012) Evaluation of post operative shoulder tip pain in low pressure versus standard pressure pneumoperitoneum during laparoscopic cholecystectomy. Surgeon 10:71–74

    Article  PubMed  Google Scholar 

  26. Gurusamy KS, Samraj K, Davidson BR (2009) Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy. Cochrane Database Syst Rev 15:CD006930. doi:10.1002/14651858.CD006930.pub2

  27. Koivusalo AM, Kellokumpu I, Lindgren L (1996) Gasless laparoscopic cholecystectomy: comparison of postoperative recovery with conventional technique. Br J Anaesth 77:576–580

    Article  PubMed  CAS  Google Scholar 

  28. Larsen JF, Ejstrud P, Kristensen JU, Svendsen F, Redke F, Pedersen V (2001) Randomized comparison of conventional and gasless laparoscopic cholecystectomy: operative technique, postoperative course, and recovery. J Gastrointest Surg 5:330–335

    Article  PubMed  CAS  Google Scholar 

  29. Lindgren L, Koivusalo AM, Kellokumpu I (1995) Conventional pneumoperitoneum compared with abdominal wall lift for laparoscopic cholecystectomy. Br J Anaesth 75:567–572

    Article  PubMed  CAS  Google Scholar 

  30. Talwar N, Pusuluri R, Arora MP, Pawar M (2006) Randomized controlled trial of conventional carbon dioxide pneumoperitoneum versus gasless technique for laparoscopic cholecystectomy. JK Sci 8:73–78

    Google Scholar 

  31. Uen YH, Chen Y, Kuo CY, Wen KC, Koay LB (2007) Randomized trial of low-pressure carbon dioxide-elicited pneumoperitoneum versus abdominal wall lifting for laparoscopic cholecystectomy. J Chin Med Assoc 70:324–330

    Article  PubMed  Google Scholar 

  32. Uen YH, Liang AI, Lee HH (2002) Randomized comparison of conventional carbon dioxide insufflation and abdominal wall lifting for laparoscopic cholecystectomy. J Laparoendosc Adv Surg Tech A 12:7–14

    Article  PubMed  Google Scholar 

  33. Vezakis A, Davides D, Gibson JS, Moore MR, Shah H, Larvin M, McMahon MJ (1999) Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy. Surg Endosc 13:890–893

    Article  PubMed  CAS  Google Scholar 

  34. Gurusamy Kurinchi S, Samraj K, Davidson Brian R (2008) Abdominal lift for laparoscopic cholecystectomy. Cochrane Database Syst Rev. doi:10.1002/14651858.CD006574.pub2

    Google Scholar 

  35. Jorgensen JO, Gillies RB, Hunt DR, Caplehorn JR, Lumley T (1995) A simple and effective way to reduce postoperative pain after laparoscopic cholecystectomy. Aust N Z J Surg 65:466–469

    Article  PubMed  CAS  Google Scholar 

  36. Berberoglu M, Dilek ON, Ercan F, Kati I, Ozmen M (1998) The effect of CO2 insufflation rate on the postlaparoscopic shoulder pain. J Laparoendosc Adv Surg Tech A 8:273–277

    Article  PubMed  CAS  Google Scholar 

  37. Aitola P, Airo I, Kaukinen S, Ylitalo P (1998) Comparison of N2O and CO2 pneumoperitoneums during laparoscopic cholecystectomy with special reference to postoperative pain. Surg Laparosc Endosc 8:140–144

    Article  PubMed  CAS  Google Scholar 

  38. Atak I, Ozbagriacik M, Akinci OF, Bildik N, Subasi IE, Ozdemir M, Ayta NI (2011) Active gas aspiration to reduce pain after laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech 21:98–100

    Article  PubMed  Google Scholar 

  39. Wallace DH, Serpell MG, Baxter JN, O’Dwyer PJ (1997) Randomized trial of different insufflation pressures for laparoscopic cholecystectomy. Br J Surg 84:455–458

    Article  PubMed  CAS  Google Scholar 

  40. Al Shehri MY (1999) Radiological evaluation of patients after laparoscopic cholecystectomy. Saudi J Gastroenterol 5:23–26

    PubMed  CAS  Google Scholar 

  41. Draper K, Jefson R, Jongeward R Jr, McLeod M (1997) Duration of postlaparoscopic pneumoperitoneum. Surg Endosc 11:809–811

    Article  PubMed  CAS  Google Scholar 

  42. Jackson SA, Laurence AS, Hill JC (1996) Does post-laparoscopy pain relate to residual carbon dioxide? Anaesthesia 51:485–487

    Article  PubMed  CAS  Google Scholar 

  43. Tzovaras G, Liakou P, Fafoulakis F, Baloyiannis I, Zacharoulis D, Hatzitheofilou C (2009) Is there a role for drain use in elective laparoscopic cholecystectomy? A controlled randomized trial. Am J Surg 197:759–763

    Article  PubMed  Google Scholar 

  44. Uchiyama K, Tani M, Kawai M, Terasawa H, Hama T, Yamaue H (2007) Clinical significance of drainage tube insertion in laparoscopic cholecystectomy: a prospective randomized controlled trial. J Hepatobiliary Pancreat Surg 14:551–556

    Article  PubMed  Google Scholar 

  45. Fredman B, Jedeikin R, Olsfanger D, Flor P, Gruzman A (1994) Residual pneumoperitoneum: a cause of postoperative pain after laparoscopic cholecystectomy. Anesth Analg 79:152–154

    PubMed  CAS  Google Scholar 

  46. Alijani A, Hanna GB, Cuschieri A (2004) Abdominal wall lift versus positive-pressure capnoperitoneum for laparoscopic cholecystectomy: randomized controlled trial. Ann Surg 239:388–394

    Article  PubMed  Google Scholar 

  47. Koivusalo AM, Kellokumpu I, Scheinin M, Tikkanen I, Makisalo H, Lindgren L (1998) A comparison of gasless mechanical and conventional carbon dioxide pneumoperitoneum methods for laparoscopic cholecystectomy. Anesth Analg 86:153–158

    PubMed  CAS  Google Scholar 

  48. Ninomiya K, Kitano S, Yoshida T, Bandoh T, Baatar D, Matsumoto T (1998) Comparison of pneumoperitoneum and abdominal wall lifting as to hemodynamics and surgical stress response during laparoscopic cholecystectomy. Surg Endosc 12:124–128

    Article  PubMed  CAS  Google Scholar 

  49. Uemura N, Nomura M, Inoue S, Endo J, Kishi S, Saito K, Ito S, Nakaya Y (2002) Changes in hemodynamics and autonomic nervous activity in patients undergoing laparoscopic cholecystectomy: differences between the pneumoperitoneum and abdominal wall-lifting method. Endoscopy 34:643–650

    Article  PubMed  CAS  Google Scholar 

  50. Dexter SP, Vucevic M, Gibson J, McMahon MJ (1999) Hemodynamic consequences of high- and low-pressure capnoperitoneum during laparoscopic cholecystectomy. Surg Endosc 13:376–381

    Article  PubMed  CAS  Google Scholar 

  51. Gutt CN, Oniu T, Mehrabi A, Schemmer P, Kashfi A, Kraus T, Buchler MW (2004) Circulatory and respiratory complications of carbon dioxide insufflation. Dig Surg 21:95–105

    Article  PubMed  CAS  Google Scholar 

  52. Hasukic S (2005) Postoperative changes in liver function tests: randomized comparison of low- and high-pressure laparoscopic cholecystectomy. Surg Endosc 19:1451–1455

    Article  PubMed  CAS  Google Scholar 

  53. Di Massa A, Avella R, Gentili C (1996) Respiratory dysfunction related to diaphragmatic shoulder pain after abdominal and pelvic laparoscopy. Minerva Anestesiol 62:171–176

    PubMed  Google Scholar 

  54. Schulz KF, Altman DG, Moher D (2011) CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. Int J Surg 9:672–677

    Article  PubMed  Google Scholar 

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Disclosures

Anders Meller Donatsky, Flemming Bjerrum, and Ismail Gögenur have no conflict of interest or financial ties to disclose.

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Donatsky, A.M., Bjerrum, F. & Gögenur, I. Surgical techniques to minimize shoulder pain after laparoscopic cholecystectomy. A systematic review. Surg Endosc 27, 2275–2282 (2013). https://doi.org/10.1007/s00464-012-2759-5

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