Abstract
Growing-up milks (GUM) are milk-based drinks with low protein and added minerals and vitamins intended for children 12–36 months. Since the advantages of GUM are heavily debated, we reviewed the literature. A literature search was done using the classic databases (Pubmed, Embase, Cochrane) on the use of GUM in 12- to 36-month-old young children. Only limited data are available. GUM have a highly variable composition as their marketing is not regulated. Nevertheless, all papers conclude that GUM help to cover nutritional requirements of 12- to 36-month-old infants. Conclusion: Appropriate intakes of macro- and micronutrients in 1- to 3-year-old children have long-term health benefits. Present diets offered to toddlers do in general not meet the requirements. Supplemented foods are therefore helpful, of which GUM is a possibility.
Abbreviations
- EFSA:
-
European Food Safety Authority
- ESPGHAN:
-
European Society of Paediatric Gastroenterology, Hepatology and Nutrition
- GUM:
-
Growing-up milk
- NPNS:
-
National Pre-school Nutrition Survey
- PRI:
-
Population Reference Intake
- RDA:
-
Recommended Daily Intake
- WHO:
-
World Health Organisation
References
Agostoni C, Decsi T, Fewtrell M, Goulet O, Kolacek S, Koletzko B, Michaelsen KF, Moreno L, Puntis J, Rigo J, Shamir R, Szajewska H, Turck D, van Goudoever J, ESPGHAN Committee on Nutrition (2008) Complementary feeding: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 46(1):99–110
Agostoni C, Scaglioni S, Ghisleni D, Verduci E, Giovannini M, Riva E (2005) How much protein is safe? Int J Obes (Lond) 29(2):S8–S13
Agostoni C, Zuccotti GV, Radaelli G, Besana R, Podestà A, Sterpa A, Rottoli A, Riva E, Giovannini M (2009) Docosahexaenoic acid supplementation and time at achievement of gross motor milestones in healthy infants: a randomized, prospective, double-blind, placebo-controlled trial. Am J Clin Nutr 89(1):64–70
Braegger C, Campoy C, Colomb V, Decsi T, Domellof M, Fewtrell M, Hojsak I, Mihatsch W, Molgaard C, Shamir R, Turck D, van Goudoever J, ESPGHAN Committee on Nutrition (2013) Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr 56(6):692–701
Briefel R, Hanson C, Fox MK, Novak T, Ziegler P (2006) Feeding Infants and Toddlers Study: do vitamin and mineral supplements contribute to nutrient adequacy or excess among US infants and toddlers? J Am Diet Assoc 106(1):S52–S65
Daly A, MacDonald A, Aukett A, Williams J, Wolf A, Davidson J, Booth IW (1996) Prevention of anaemia in inner city toddlers by an iron supplemented cows' milk formula. Arch Dis Child 75(1):9–16
Dietary feeding habits of babies and toddlers in Belgium, health through food (HTF), Ipsos Ltd 2012
Dietary fFeeding habits of 6–36 months old babies and toddlers in Belgium, Feeding for life (FFL), Ipsos Ltd 2008
European Food Safety Authority (EFSA) Scientific opinion on dietary reference values for energy. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) 11:3005
European Food Safety Authority (EFSA) (2012) Scientific opinion on dietary reference values for protein1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). EFSA J 10:2557
European Food Safety Authority (EFSA) (2013) Panel on dietetic products, nutrition and allergies. Scientific opinion on nutrient requirements and dietary intakes of infants and young children in the European Union. EFSA Journal 11:3408
European Food Safety Authority. Request for an EFSA scientific opinion on the composition of milk based-drinks and similar products intended for infants and young children. EFSA register of Questions. M-2013-0088. http://registerofquestions.efsa.europa.eu/roqFrontend/questionsListLoader?unit=NUTRI (assessed May 2013)
Fleischer Michaelsen K, Weaver L, Branca F, Robertson A (2003) Feeding and nutrition of infants and young children. Guidelines for the WHO European region, with emphasis on the former Soviet countries. WHO regional Publications, European Series, No. 87. Copenhagen, WHO Regional Office for Europe
Ghisolfi J, Fantino M, Turck D, de Courcy GP, Vidailhet M (2013) Nutrient intakes of children aged 1–2 years as a function of milk consumption, cow’s milk or growing-up milk. Public Health Nutr 16(3):524–534
Gilbert-Diamond D, Baylin A, Mora-Plazas M, Marin C, Arsenault JE, Hughes MD, Willett WC, Villamor E (2010) Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study. Am J Clin Nutr 92(6):1446–1451
Gordon CM, Feldman HA, Sinclair L, Williams AL, Kleinman PK, Perez-Rossello J, Cox JE (2008) Prevalence of vitamin D deficiency among healthy infants and toddlers. Arch Pediatr Adolesc Med 162(6):505–512
Günther AL, Buyken AE, Kroke A (2007) Protein intake during the period of complementary feeding and early childhood and the association with body mass index and percentage body fat at 7 y of age. Am J Clin Nutr 85(6):1626–1633
Günther AL, Remer T, Kroke A, Buyken AE (2007) Early protein intake and later obesity risk: which protein sources at which time points throughout infancy and childhood are important for body mass index and body fat percentage at 7 y of age? Am J Clin Nutr 86(6):1765–1772
Houghton LA, Gray AR, Szymlek-Gay EA, Heath AL, Ferguson EL (2011) Vitamin D-fortified milk achieves the targeted serum 25-hydroxyvitamin D concentration without affecting that of parathyroid hormone in New Zealand toddlers. J Nutr 141(10):1840–1846
Hower J, Knoll A, Ritzenthaler KL, Steiner C, Berwind R (2013) Vitamin D fortification of growing up milk prevents decrease of serum 25-hydroxyvitamin D concentrations during winter: a clinical intervention study in Germany. Eur J Pediatr 172(12):1597–1605
Huybrechts I, De Henauw S (2007) Energy and nutrient intakes by pre-school children in Flanders-Belgium. Br J Nutr 98(3):600–610
Huybrechts I, Lin Y, De Keyzer W, Sioen I, Mouratidou T, Moreno LA, Slimani N, Jenab M, Vandevijvere S, De Backer G, De Henauw S (2011) Dietary sources and sociodemographic and economic factors affecting vitamin D and calcium intakes in Flemish preschoolers. Eur J Clin Nutr 65(9):1039–1047
Huysentruyt K, Hauser B, Van de Sompel A, Laire D, Van Avondt T, De Schepper J, Vandenplas Y. L'effet sur l'apport en proteins des jeunes enfants belges en remplaçant le lait par du lait de croissance. 35ème Congres Du Groupe Francophone d'Hépatologie, Gastroentérologie et Nutrition Pédiatriques 2014 (abstract).
Huysentruyt K, Van de Sompel A, Laire D, Van AVondt T, D Schepper J, Vandenplas Y. Milk intake in Belgian toddlers: does growing up milk have a place? Espghan 2014 (accepted abstract).
Irish Universities Nutrition Alliance. National preschool nutrition survey main report. www.iuna.net (assessed May 2013)
Koletzko B, von Kries R, Closa R, Escribano J, Scaglioni S, Giovannini M, Beyer J, Demmelmair H, Gruszfeld D, Dobrzanska A, Sengier A, Langhendries JP, Rolland Cachera MF, Grote V, European Childhood Obesity Trial Study Group (2009) Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial. Am J Clin Nutr 89(6):1836–1845
Male C, Persson LA, Freeman V, Guerra A, van't Hof MA, Haschke F, Euro-Growth Iron Study Group (2001) Prevalence of iron deficiency in 12-mo-old infants from 11 European areas and influence of dietary factors on iron status (Euro-Growth study). Acta Paediatr 90(5):492–498
Mallet E, Gaudelus J, Reinert P, Stagnara J, Bénichou J, Castanet M, Thill C, Basuyau JP, Billard C, Roden A, Uhlrich J (2012) Prophylactic prescription of vitamin D in France: national multicenter epidemiological study of 3240 children under 6 years of age. Arch Pediatr 19(12):1293–1302
Marcy TR, Britton ML, Harrison D (2011) Identification of barriers to appropriate dietary behavior in low-income patients with type 2 diabetes mellitus. Diabetes Ther 2(1):9–19
Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M, Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society (2008) Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 122(2):398–417
Mullie P, Clarys P, Hulens M, Vansant G (2010) Dietary patterns and socioeconomic position. Eur J Clin Nutr 64(3):231–238
Nutrient reference values for Australia and New Zealand including recommended dietary intakes. Australian Government Department of Health and Ageing. National Health and Medical Research Council 2005
Przyrembel H, Agostoni B (2013) Growing-up milk: a necessity or marketing? In: Szajewska H, Shamir R (eds): Evidence-based research in pediatric nutrition. World Rev Nutr Diet. 108:49–55
Rolland-Cachera MF, Deheeger M, Akrout M, Bellisle F (1995) Influence of macronutrients on adiposity development: a follow up study of nutrition and growth from 10 months to 8 years of age. Int J Obes Relat Metab Disord 19(8):573–578
Scaglioni S, Agostoni C, Notaris RD, Radaelli G, Radice N, Valenti M, Giovannini M, Riva E (2000) Early macronutrient intake and overweight at five years of age. Int J Obes Relat Metab Disord 24(6):777–781
Sioen I, Huybrechts I, Verbeke W, Camp JV, De Henauw S (2007) n-6 and n-3 PUFA intakes of pre-school children in Flanders, Belgium. Br J Nutr 98(4):819–825
Townsend E, Pitchford NJ (2012) Baby knows best? The impact of weaning style on food preferences and body mass index in early childhood in a case-controlled sample. BMJ Open 6:e000298
Uijterschout L, Vloemans J, Vos R, Teunisse PP, Hudig C, Bubbers S, Verbruggen S, Veldhorst M, de Leeuw T, van Goudoever JB, Brus F (2014) Prevalence and risk factors of iron deficiency in healthy young children in the southwestern Netherlands. J Pediatr Gastroenterol Nutr 58(2):195–200
Walton J, ed. National pre-school nutrition survey — summary report. www.iuna.net; 2012 (assessed May 2013)
Walton J, Flynn A (2013) Nutritional adequacy of diets containing growing up milks or unfortified cow's milk in Irish children (aged 12–24 months). Food Nutr Res 57:21836
Weber M, Grote V, Closa-Monasterolo R, Escribano J, Langhendries JP, Dain E, Giovannini M, Verduci E, Gruszfeld D, Socha P, Koletzko B; for The European Childhood Obesity Trial Study Group (2014) Lower protein content in infant formula reduces BMI and obesity risk at school age: follow-up of a randomized trial. Am J Clin Nutr (in press)
Williams J, Wolff A, Daly A, MacDonald A, Aukett A, Booth IW (1999) Iron supplemented formula milk related to reduction in psychomotor decline in infants from inner city areas: randomised study. BMJ 318(7185):693–697
Conflict of interest
No potential COI of any of the authors regarding this manuscript.
Author contributions
Y Vandenplas has participated as a clinical investigator, and/or advisory board member, and/or consultant, and/or speaker for Abbott Nutrition, Biogaia, Biocodex, Danone, Hero, Nestle Nutrition Institute, Nutricia, Mead Johnson, Merck, Orafti, Pfizer, Phacobel, Sari Husada, Sucampo, Takeda, United Pharmaceuticals, Wyeth and Yakult.
J. Rigo has participated as a clinical investigator, and/or advisory board member, and/or consultant, and/or speaker for Abbott, Baxter Healthcare, Danone, Mead Johnson, Nestle Nutrition
Daniel Brasseur is a member of the Danone Institute.
P. Goyens is a consultant and/or investigator and/or speaker for Danone Waters, Merck Serono and Vertex Pharmaceuticals.
I. Scheers, AM Van De Sompel, M. Robert, N. De Ronne, K. Huysentruyt have no potential conflict of interest to declare.
Author information
Authors and Affiliations
Corresponding author
Additional information
Communicated by Peter de Winter
Rights and permissions
About this article
Cite this article
Vandenplas, Y., De Ronne, N., Van De Sompel, A. et al. A Belgian consensus-statement on growing-up milks for children 12–36 months old. Eur J Pediatr 173, 1365–1371 (2014). https://doi.org/10.1007/s00431-014-2321-7
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00431-014-2321-7