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The effects of detraining on blood adipokines and antioxidant enzyme in Korean overweight children

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Abstract

The present study examined the change to clarify the effects of detraining on the concentration of lipid profiles, serum adipokines and antioxidant enzyme gene expression in Korean overweight children. The subjects were normal children (n = 19) and obese children (n = 20) who were further subdivided into the overweight training (OT) group (n = 10) and the overweight detraining (OD) group (n = 10). Maximal oxygen uptake (VO2max); body composition; lipid profiles (TG, TC); adipokines (adiponectin and leptin); antioxidants (blood and gene expressions SOD and GPX) were measured before, 12 weeks, and 24 weeks after the exercise program. Body mass index (BMI) and %fat were significantly higher in the OD group only. However, waist hip ration (WHR) and systolic blood pressure (SBP) were significantly decreased in the OT group. TG was significantly decreased in the OT group. There was a significant difference in TG level between the two groups. Besides, adiponectin was significantly increased in both the OT group and the OD group. Furthermore, leptin was significantly decreased in the OT group. There was a significant difference in leptin level between the two groups. In training groups, the expression of SOD was significantly increased after a 12- and 24-week period (p < 0.05). However, detraining group was significantly increased after a 12-week only (p < 0.05). In addition, GPX was significantly increased after a 24-week only in the training group (p < 0.05). Thus, detraining showed that negative effected on body composition and lipid profiles and maintained of uniform period on adipokines and antioxidant enzyme the protein and expression.

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Acknowledgements

This study was supported by Dong-A University research fund.

Conflict of interest

The authors declare that they have no conflict of interest. This study was not sponsored by any external organization.

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Authors and Affiliations

  1. Laboratory of Exercise Physiology, Department of Physical Education, College of Sports Science, Dong-A University, 840 Hadan2-dong, Saha-gu, Busan, 604-714, South Korea

    Jinhee Woo, Ki Ok Shin & Sunghwun Kang

  2. Department of Pediatrics, College of Medicine, Dong-A University, Busan, South Korea

    Jae-Ho Yoo

  3. Department of Pharmacology, Medical Sciences Research Institute, College of Medicine, Dong-A University, Busan, South Korea

    Soyoung Park & Sunghwun Kang

Authors
  1. Jinhee Woo
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  2. Ki Ok Shin
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  3. Jae-Ho Yoo
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  4. Soyoung Park
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  5. Sunghwun Kang
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Correspondence to Sunghwun Kang.

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Woo, J., Shin, K.O., Yoo, JH. et al. The effects of detraining on blood adipokines and antioxidant enzyme in Korean overweight children. Eur J Pediatr 171, 235–243 (2012). https://doi.org/10.1007/s00431-011-1518-2

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  • DOI: https://doi.org/10.1007/s00431-011-1518-2

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