Skip to main content
SpringerLink
Log in

Emerging roles of transporter-PDZ complexes in renal proximal tubular reabsorption

  • Frontiers in Physiology
  • Published:
Pflügers Archiv Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bezprozvanny I, Maximov A (2001) PDZ domains: more than just a glue. Proc Natl Acad Sci USA 98:787–789

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Cao TT, Deacon HW, Reczek D, Bretscher A, Zastrow M (1999) A kinase-regulated PDZ-domain interaction controls endocytic sorting of the ß2-adrenergic receptor. Nature 401:286–289

    Article  CAS  PubMed  Google Scholar 

  3. Fanning AS, Anderson JM (1999) PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. J Clin Invest 103:767–772

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Garner CC, Nash J, Huganir RL (2000) PDZ domains in synapse assembly and signalling. Trends Cell Biol 10:274–280

    Article  CAS  PubMed  Google Scholar 

  5. Gisler SM, Stagljar I, Traebert M, Bacic D, Biber J, Murer H (2001) Interaction of the type IIa Na/Pi -cotransporter with PDZ proteins. J Biol Chem 276:9206–9213

    Article  CAS  PubMed  Google Scholar 

  6. Hall RA, Ostedgaad LS, Premont RT, Blitzer JT, Rahman N, Welsh MJ, Lefkowitz RJ (1998) A C-terminal motif found in the ß2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na/H exchanger regulatory factor family of PDZ proteins. Proc Natl Acad Sci USA 95:8496–8501

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  7. Karim-Jimenez Z, Hernando N, Biber J, Murer H (2001) Molecular determinants for apical expression of the renal type lla Na/Pi-cotransporter. Pflügers Arch (in press) DOI s004240100602

  8. Kocher O, Comella N, Gilchrist A, Pal R, Tognazzi K, Brown LF, Knoll JHM (1999) PDKZ1, a novel PDZ domain containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT ( MRP2), the multidrug resistance associated protein. Lab Invest 79:1161–1170

    CAS  PubMed  Google Scholar 

  9. Moe OW (1999) Acute regulation of proximal tubule apical membrane Na/H exchanger NHE3: role of phosphorylation, protein trafficking and regulatory factors. J Am Soc Nephrol 10:2412–2425

    CAS  PubMed  Google Scholar 

  10. Murer H, Biber J (1997) A molecular view of proximal tubular inorganic phosphate (Pi) reabsorption and of its regulation. Pflügers Arch 433:379–389

    Article  CAS  PubMed  Google Scholar 

  11. Reczek D, Bretscher A (2001) Identification of EPI64, a TBC/ rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP. J Cell Biol 153:191–205

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  12. Shenolikar S, Weinman EJ (2001) NHERF: targeting and trafficking membrane proteins. Am J Physiol 280:F389–F395

    Google Scholar 

  13. Tomita S, Nicoll RA, Bredt DS (2001) PDZ protein interactions regulating glutamate receptor function and plasticity. J Cell Biol 153:F19–F23

    Article  PubMed Central  Google Scholar 

  14. Weinman E, Minkoff C, Shenolikar S (2000) Signal complex regulation of renal transport: NHERF and regulation of NHE3 by PKA. Am J Physiol 279:F393–F399

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland

    J. Biber

Authors
  1. J. Biber
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J. Biber.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Biber, J. Emerging roles of transporter-PDZ complexes in renal proximal tubular reabsorption. Pflügers Arch - Eur J Physiol 443, 3 (2001). https://doi.org/10.1007/s004240100721

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004240100721

Keywords

Search

Navigation