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Organic anion transport is the primary function of the SLC17/type I phosphate transporter family

  • The ABC of Solute Carriers
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Abstract

Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitter glutamate to the degradation and metabolism of glycoproteins.

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Acknowledgements

The authors are supported in part by funding from the NINDS (R.H.E. and R.J.R.), NIDA (R.H.E.) and NIMH (R.H.E.).

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Authors and Affiliations

  1. Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA

    Richard J. Reimer

  2. Departments of Neurology and Physiology, Graduate Programs in Neuroscience and Cell Biology, University of California, San Francisco, CA 94143, USA

    Robert H. Edwards

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Correspondence to Richard J. Reimer.

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Reimer, R.J., Edwards, R.H. Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Pflugers Arch - Eur J Physiol 447, 629–635 (2004). https://doi.org/10.1007/s00424-003-1087-y

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  • DOI: https://doi.org/10.1007/s00424-003-1087-y

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