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Outcome of optical iridectomy in Peters anomaly

  • Cornea
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Abstract

Purpose

Optical iridectomy creates a defect in the iris to allow an alternative clear visual axis in cases of central corneal opacities occluding the pupillary axis. The purpose of this study is to evaluate the outcomes of optical sector iridectomy in children with Peters anomaly.

Methods

Retrospective case series. The medical records of all patients diagnosed with Peters anomaly who underwent optical iridectomy during the years 2002–2014 were reviewed. Data collection included surgical and visual acuity outcomes.

Results

Twenty-nine eyes (22 patients) were included in the study. Mean age at the time of surgery was 15.6 ± 26.3 months. Eighteen (81.8%) patients had bilateral disease. No intraoperative complications occurred. A red reflex was obtained in 28 (96.6%) eyes after surgery. Mean visual acuity improved from 2.5 ± 0.3 to 1.8 ± 0.6 in logMAR (p < 0.001). Vision improved in 21 (72.4%) eyes, remained stable in 5 (17.2%) eyes, and deteriorated in 3 (10.3%) eyes. Postoperatively visual acuity improved significantly in the patients with the bilateral disease (p < 0.05), but not in the unilateral group (p = 0.056). Mean follow-up time was 41.6 ± 43.8 months. During the follow-up period, five (17.2%) eyes were diagnosed with glaucoma, two (6.9%) eyes underwent PK, one (3.4%) eye underwent an additional sector iridectomy, and one (3.4%) eye underwent keratoprosthesis.

Conclusions

In this largest series published of optical iridectomy for Peters anomaly, it was found to be a safe procedure. Improvement in visual acuity is expected, particularly in bilateral cases. The utility of optical iridectomy in unilateral cases necessitates further studies.

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Funding

This study was supported by the Research to Prevent Blindness Unrestricted Grant (New York, New York) and by the National Eye Institute core grant P30-EY14801 (Bethesda, Maryland). The sponsors had no role in the design or conduct of this research.

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Authors and Affiliations

  1. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St 450N, Miami, FL, 33136, USA

    Oriel Spierer, Kara M. Cavuoto, Sirinya Suwannaraj, Craig A. McKeown & Ta Chen Chang

  2. Ophthalmology Division, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Oriel Spierer

  3. Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

    Sirinya Suwannaraj

Authors
  1. Oriel Spierer
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  2. Kara M. Cavuoto
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  3. Sirinya Suwannaraj
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  4. Craig A. McKeown
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  5. Ta Chen Chang
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Corresponding author

Correspondence to Ta Chen Chang.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the University of Miami research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

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Spierer, O., Cavuoto, K.M., Suwannaraj, S. et al. Outcome of optical iridectomy in Peters anomaly. Graefes Arch Clin Exp Ophthalmol 256, 1679–1683 (2018). https://doi.org/10.1007/s00417-018-4000-2

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  • DOI: https://doi.org/10.1007/s00417-018-4000-2

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