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Hydrophobic acrylic versus polymethyl methacrylate intraocular lens implantation following cataract surgery in the first year of life

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Abstract

Purpose

To evaluate complication rates following implantation of hydrophobic acrylic versus polymethyl methacrylate (PMMA) intraocular lens (IOL) with cataract surgery in infants.

Methods

Records of children undergoing cataract surgery with IOL implantation in first year of life were retrospectively reviewed. Infants were divided into two groups—hydrophobic acrylic IOLs were implanted in group A, and PMMA IOLs in group B. Outcome measures included incidence of complications, additional surgical procedures, and refractive error changes.

Results

One hundred and thirteen eyes of 113 children (75 males) with mean age of 6.49 ± 3.56 months were included. Group A included 62 eyes, and group B included 51 eyes. The two groups did not differ significantly in terms of age and axial length. There was no significant difference between the groups for incidence of posterior capsular opacification (PCO), pupillary membranes, glaucoma, fibrin on IOL surface or IOL malposition (p = 0.09). Development of PCO was delayed in group A (p = 0.049). Thirteen eyes of group A and 18 eyes of group B required additional surgical intervention (p = 0.20) in the follow-up visits.

Conclusion

Comparable complications may be expected in infants with PMMA and hydrophobic acrylic lenses. Children implanted with PMMA IOLs may require earlier surgical re-intervention for PCO.

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References

  1. Lundvall A, Zetterström C (2006) Primary intraocular lens implantation in infants: complications and visual results. J Cataract Refract Surg 32:1672–1677

    Article  PubMed  Google Scholar 

  2. Lambert SR, Lynn M, Drews-Botsch C, DuBois L, Wilson ME, Plager DA et al (2003) Intraocular lens implantation during infancy: perception of parents and the American Association for Pediatric Ophthalmology and Strabismus member. J AAPOS 7:400–405

    Article  PubMed  Google Scholar 

  3. Nischal KK, Solebo L, Russell-Eggitt I (2010) Paediatric IOL implantation and postoperative refractive state: what role do study methodology and surgical technique play? Br J Ophthalmol 94:529–531

    Article  PubMed  Google Scholar 

  4. Fan DS, Yip WW, Yu CB, Rao SK, Lam DS (2006) Updates on the surgical management of paediatric cataract with primary intraocular lens implantation. Ann Acad Med Singap 35:564–570

    PubMed  Google Scholar 

  5. Trivedi RH, Wilson ME, Vasavada AR, Shah SK, Vasavada V, Vasavada VA (2011) Visual axis opacification after cataract surgery and hydrophobic intraocular lens implantation in the first year of life. J Cataract Refract Surg 37:83–87

    Article  PubMed  Google Scholar 

  6. Ram J, Brar GS, Kaushik S, Sukhija J, Bandyopadhyay S, Gupta A (2007) Primary intraocular lens implantation in the first two years of life: safety profile and visual results. Indian J Ophthalmol 55:185–189

    Article  PubMed  Google Scholar 

  7. Bhusal S, Ram J, Sukhija J, Pandav SS, Kaushik S (2010) Comparison of the outcome of implantation of hydrophobic acrylic versus silicone intraocular lens in pediatric cataract: prospective randomized study. Can J Ophthalmol 45:531–536

    Article  PubMed  Google Scholar 

  8. Trivedi RH, Wilson ME Jr (2003) Single piece acrylic intraocular lens implantation in children. J Cataract Refract Surg 29:1738–1743

    Article  PubMed  Google Scholar 

  9. Vanderveen DK, Nizam A, Lynn MJ, Bothun ED, McClatchey SK, Weakley DR et al (2012) Infant Aphakia Treatment Study Group. Predictability of intraocular lens calculation and early refractive status. Arch Ophthalmol 130:293–299

    Article  PubMed Central  PubMed  Google Scholar 

  10. Tromans C, Haigh PM, Biswas S, Lloyd IC (2001) Accuracy of intraocular lens power calculation in paediatric cataract surgery. Br J Ophthalmol 85:939–941

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  11. Kirwan C, Lanigan B, O’ Keefe M (2010) Glaucoma in aphakic and pseudophakic eyes following surgery for congenital cataract in the first year of life. Acta Ophthalmol 88:53–59

    Article  PubMed  Google Scholar 

  12. Gupta A, Kekunnaya R, Ramappa M, Vaddavalli PK (2011) Safety profile of primary intraocular lens implantation in children below 2 years of age. Br J Ophthalmol 95:477–480

    Article  PubMed  Google Scholar 

  13. Plager DA, Yang S, Neely D, Sprunger D, Sondhi N (2002) Complications in the first year following cataract surgery with and without IOL in infants and older children. J AAPOS 6:9–14

    Article  PubMed  Google Scholar 

  14. Apple DJ, Solomon KD, Tetz MR et al (1992) Posterior capsule opacification. Surv Ophthalmol 37:73–116

    Article  CAS  PubMed  Google Scholar 

  15. Llyod IC, Ashworth J, Biswas S, Abadi RV (2007) Advances in the management of congenital and infantile cataract. Eye 21:1301–1309

    Article  Google Scholar 

  16. Ram J, Brar GS, Kaushik S, Gupta A, Gupta A (2003) Role of posterior capsulotomy with vitrectomy and intraocular lens design and material in reducing posterior capsule opacification after pediatric cataract surgery. J Cataract Refract Surg 29:1579–1584

    Article  PubMed  Google Scholar 

  17. Rowe NA, Biswas S, Lloyd IC (2004) Primary IOL implantation in children: a risk analysis of foldable acrylic v/s PMMA lenses. Br J Ophthalmol 88:481–485

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  18. Hayashi K, Hideyuki H, Nakao F et al (2001) Changes in posterior capsule opacification after poly(methyl methacrylate), silicone, and acrylic intraocular lens implantation. J Cataract Refract Surg 27:817–824

    Article  CAS  PubMed  Google Scholar 

  19. Ram J, Apple D, Peng Q et al (1999) Update on fixation of rigid and foldable posterior chamber intraocular lenses. Part II: Choosing the correct haptic fixation and intraocular lens design to help eradicate posterior capsule opacification. Ophthalmology 106:891–900

    Article  CAS  PubMed  Google Scholar 

  20. Wilson ME, Elliott L, Johnson B, Petersein MM, Rah S, Werner L, Pandey SK (2001) AcrySof acrylic intraocular lens implantation in children: clinical indication of biocompatibility. J AAPOS 5:377–380

    Article  CAS  PubMed  Google Scholar 

  21. Küchle M, Lausen B, Gusek-Schneider GC (2003) Results and complications of hydrophobic acrylic vs PMMA posterior chamber lenses in children under 17 years of age. Graefes Arch Clin Exp Ophthalmol 241:637–641

    Article  PubMed  Google Scholar 

  22. Glynn RJ, Rosner B (1992) Accounting for the correlation between fellow eyes in regression analysis. Arch Ophthalmol 110:381–387

    Article  CAS  PubMed  Google Scholar 

  23. Dahan E, Drusedau MU (1997) Choice of lens and dioptric power in pediatric pseudophakia. J Cataract Refract Surg 23:618–623

    Article  PubMed  Google Scholar 

  24. Tuncer S, Gucukoglu A, Gozum N (2005) Cataract extraction and primary hydrophobic acrylic intraocular lens implantation in infants. J AAPOS 9:250–256

    Article  PubMed  Google Scholar 

  25. O’Keefe M, Mulvihill A, Yeoh PL (2000) Visual outcome and complications of bilateral intraocular lens implantation in children. J Cataract Refract Surg 26:1758–1764

    Article  PubMed  Google Scholar 

  26. Krishnamachary M, Rathi V, Gupta S (1997) Management of traumatic cataract in children. J Cataract Refract Surg 23:681–687

    Article  PubMed  Google Scholar 

  27. Campbell MJ (2001) Statistics at square two: understanding modern statistical applications in medicine. BMJ Books, London

    Google Scholar 

  28. Barbour W, Saika S, Miyamoto T, Ohnishi Y (2005) Biological compatibility of polymethyl methacrylate, hydrophilic acrylic and hydrophobic acrylic intraocular lenses. Ophthalmic Res 37:255–261

    Article  CAS  PubMed  Google Scholar 

  29. Hollick EJ, Spalton DJ, Ursell PG, Pande MV, Barman SA, Boyce JF, Tilling K (1999) The effect of polymethylmethacrylate, silicone, and polyacrylic intraocular lenses on posterior capsular opacification 3 years after cataract surgery. Ophthalmology 106:49–54

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

There are no financial interest(s) to disclose. No funding was received to carry out the study.

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None of the authors have any proprietary/financial or non-financial competing interest to disclose.

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The author/(s) do not have any financial or proprietary interests/affiliations or arrangements.

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Correspondence to Jagat Ram.

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Ram, J., Jain, V.K., Agarwal, A. et al. Hydrophobic acrylic versus polymethyl methacrylate intraocular lens implantation following cataract surgery in the first year of life. Graefes Arch Clin Exp Ophthalmol 252, 1443–1449 (2014). https://doi.org/10.1007/s00417-014-2689-0

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  • DOI: https://doi.org/10.1007/s00417-014-2689-0

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