References
Karmacharya P, Poudel DR, Pathak R et al (2015) Rituximab-induced serum sickness: a systematic review. Semin Arthritis Rheum 45(3):334–340
Moreira Ferreira VF, Kimbrough DJ, Stankiewicz JM (2021) A possible case of serum sickness after ocrelizumab infusion. Mult Scler 27:155–158
Rjeily NB, Nourbakhsh B, Mowry EM (2023) Serum sickness/serum sickness-like reactions following ocrelizumab infusion in 2 patients with multiple sclerosis. Int J MS Care 25(5):196–198
Kumar A, Khamkar K, Gopal H (2012) Serum sickness and severe angioedema following Rituximab therapy in RA. Int J Rheum Dis 15(1):e6–e7
Bayer G, Agier MS, Lioger B et al (2019) Rituximabinduced serum sickness is more frequent in autoimmune diseases as compared to hematological malignancies: a French nationwide study. Eur J Intern Med 67:59–64
Holmoy T, Fogdell-Hahn A, Svenningsson A (2019) Serum sickness following rituximab therapy in multiple sclerosis. Neurol Clin Pract 9(6):519–521
Wolf AB, Ryerson LZ, Pandey K et al (2019) Rituximab-induced serum sickness in multiple sclerosis patients. Mult Scler Relat Disord 36:101402
Krumbholz M, Pellkofer H, Gold R et al (2007) Delayed allergic reaction to natalizumab associated with early formation of neutralizing antibodies. Arch Neurol 64(9):1331–1333
Lapucci C, Gualandi F, Mikulska M et al (2018) Serum sickness (Like Reaction) in a patient treated with alemtuzumab for multiple sclerosis: a case report. Mult Scler Relat Disord 26:52–54
Saba J, Logan AC (2017) Obinutuzumab-induced serum sickness following salvage therapy for chronic lymphocytic leukemia. Clin Case Rep 5(6):891–893
Elmanaseer O, Avelino ARM, Azem A et al (2021) Serum sickness reaction to obinutuzumab in a patient with chronic lymphocytic leukaemia. BMJ Case Rep 14(12):e245557
Joubert M, Paris P, Clavelou P et al (2021) Ocrelizumab can be used in multiple sclerosis after a rituximab-induced serum sickness: a case report. Rev Neurol (Paris) 177(8):1041–1042
Doyle AJ, Stubbs MJ, Lester W et al (2022) The use of obinutuzumab and ofatumumab in the treatment of immune thrombotic thrombocytopenic purpura. Br J Haematol 198(2):391–396
Rapp M, Pentland A, Richardson C (2018) Successful treatment of pemphigus vulgaris with ofatumumab. J Drugs Dermatol 17(12):1338–1339
Podestà MA, Ruggiero B, Remuzzi G, Ruggenenti P (2023) Ofatumumab for multirelapsing membranous nephropathy complicated by rituximab-induced serum-sickness. BMJ Case Rep 13(1):e232896
Al-Araji S, Ciccarelli O (2021) A possible case of serum sickness after ocrelizumab infusion - Commentary. Mult Scler 27:158–159
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VM contributed to the conceptualization, gathering of data and drafting the manuscript; CC, PB, RB, and GN contributed to gathering of data and drafting the manuscript; AS contributed to drafting and revising the manuscript.
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Mantero, V., Cordano, C., Balgera, R. et al. Serum sickness in a multiple sclerosis patient treated with ocrelizumab. J Neurol 271, 727–728 (2024). https://doi.org/10.1007/s00415-023-12082-6
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DOI: https://doi.org/10.1007/s00415-023-12082-6