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Functional outcome after severe cerebral venous thrombosis

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Abstract

Severe cerebral venous thrombosis (CVT) is a rare cerebrovascular condition which in the more severe cases warrants intensive care treatment. While the outcome in the majority of uncomplicated CVT cases is good, it may be fatal in more affected patients. We provide long-term functional and quality of life (QOL) outcome data in the form of a retrospective analysis of 10 patients admitted to a neurological ICU with severe CVT. Outcome measures used were the modified Rankin Scale, the 36-item Short Form Health Survey, and the Psychological General Well-Being index. The mortality rate was 50% but 4 out 5 survivors had a good functional outcome with normal QOL despite a very severe clinical course. This finding justifies extensive life-sustaining therapy as the prognosis even of severe cases may be good if the acute phase is survived.

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Authors and Affiliations

  1. Dept. of Neurology, University of Munich Klinikum Grosshadern, Marchioninistr 15, 81377, Munich, Germany

    Andreas Bender MD, Gernot Schulte-Altedorneburg MD, Thomas Pfefferkorn MD, Tobias Birnbaum MD, Berend Feddersen MD, Hans-Walter Pfister MD & Andreas Straube

  2. Dept. of Neuroradiology, University of Munich Klinikum Grosshadern (Munich), Germany

    Thomas E. Mayer MD & Hartmut Brückmann MD

Authors
  1. Andreas Bender MD
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  2. Gernot Schulte-Altedorneburg MD
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  3. Thomas E. Mayer MD
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  4. Thomas Pfefferkorn MD
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  5. Tobias Birnbaum MD
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  6. Berend Feddersen MD
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  7. Hartmut Brückmann MD
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  8. Hans-Walter Pfister MD
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  9. Andreas Straube
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Corresponding author

Correspondence to Andreas Bender MD.

Additional information

A. Bender and G. Schulte-Altedorneburg contributed equally.

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Bender, A., Schulte-Altedorneburg, G., Mayer, T.E. et al. Functional outcome after severe cerebral venous thrombosis. J Neurol 254, 465–470 (2007). https://doi.org/10.1007/s00415-006-0391-9

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  • DOI: https://doi.org/10.1007/s00415-006-0391-9

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