Skip to main content
Log in

Evaluation of hearing loss and tinnitus in Behcet’s disease

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objective

The aim of this study is to evaluate sensorineuralhearing loss (SHNL) and tinnitus in patients with Behcet’s disease (BD), while also determining the association between the clinical symptoms of BD and the disease duration with the development of hearing loss.

Materials and methods

The study included 44 patients with BD and 42 healthy volunteers as the control group. The level of tinnitus-induced annoyance and the effects of tinnitus on daily life were evaluated with Visual Analog Scale (VAS) and the Tinnitus Reaction Questionnaire (TRQ). The hearing levels of all participants were measured with high-frequency audiometry and transient auto-acoustic emission tests.

Results

The patients with BD were significantly more affected by SNHL and tinnitus than the controls (p < 0.05). The correlation between disease duration and age among those with SNHL was statistically significant (p < 0.05). No association was found between the clinical findings and SNHL and tinnitus (p > 0.05) in the BD patients.

Conclusion

In the present study, high-frequency SNHL was found to be common in among the patients with BD. SNHL in BD is positively correlated with the patients’ age of the and the disease duration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Alpsoy E (2005) Behçet’s disease: treatment of mucocutaneous lesions. Clin Exp Rheumatol 23:532–539

    PubMed  CAS  Google Scholar 

  2. Greco A, De Virgilio A, Ralli M, Ciofalo A et al (2018) Behçet’s disease: New insights into pathophysiology, clinical features and treatment options. Autoimmun Rev 17(6):567–575

    Article  CAS  Google Scholar 

  3. Seyahi E (2016) Behçet's disease: How to diagnose and treat vascular involvement. Best Pract Res Clin Rheumatol 30(2):279–295

    Article  Google Scholar 

  4. Ghate JV, Jorizzo JL (1999) Behcet’s disease and complex aphthosis. J Am Acad Dermatol 40:1–18

    Article  CAS  Google Scholar 

  5. Watad A, Tiosano S, Yahav D et al (2016) Behçet’s disease ‬and FMF: two sides of the same coin or just an association? A cross-sectional study. Eur J Intern Med 39:75–78

    Article  Google Scholar 

  6. Yazıcı H, Tuzun Y, Pazarlı H, Yurdakul S et al (1984) Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behçet’s syndrome. Ann Rheum Dis 43:783–789

    Article  Google Scholar 

  7. Mancini P, Atturo F, Di Mario A et al (2018) Hearing loss in autoimmune disorders: Prevalence and therapeutic options. Autoimmun Rev 17(7):644–652

    Article  Google Scholar 

  8. Ahmadzadeh A, Daraei M, Jalessi M et al (2017) Author information Hearing status in patients with rheumatoid arthritis. J Laryngol Otol 131(10):895–989

    Article  CAS  Google Scholar 

  9. Greco A, Marinelli C, A. Gallo,M, et al (2014) Immunological model and otological manifestations of Behçet's disease. Open Immunol J 7:1–7

    Article  CAS  Google Scholar 

  10. Sonbay ND, Saka C, Tatlican S, Vuralkan E, Aygener N, Eren C, Akin I (2014) Audiological evaluation in patients with Behçet's disease. J Laryngol Otol 128(8):694–697

    Article  CAS  Google Scholar 

  11. Cinar S, Cinar F, Kiran S (2012) Is there a need for audiologic evaluation in patients with Behçet disease? Ear Nose Throat J 91(3):E15–E19

    Article  Google Scholar 

  12. Barna BP, Hughes GB (1988) Autoimmunity and otologic disease: clinical and experimental aspects. Clin Lab Med 8:385–398

    Article  CAS  Google Scholar 

  13. Rossini BAA, Penido NO, Munhoz MSL et al (2017) Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases. Int Arch Otorhinolaryngol 21(3):213–223

    Article  Google Scholar 

  14. Sota J, Vitale A, Orlando I et al (2017) Auditory involvement in Behcet's disease: relationship with demographic, clinical, and therapeutic characteristics. Clin Rheumatol 36(2):445–449

    Article  Google Scholar 

  15. Morales-Angulo C, Vergara Pastrana S, Obeso-Agüera S, Acle L et al (2014) Otorhinolaryngological manifestations in patients with Behçet disease. Acta Otorrinolaringol Esp 65(1):15–21

    Article  Google Scholar 

  16. International Study Group for Behcet's Disease (1990) Criteria for diagnosis of Behcet's disease. Lancet 335:1078–1080

    Google Scholar 

  17. Guidelines for screening for hearing impairment and middle- ear disorders, (1990) Working Group on acoustic immittance measurements and the committee on audiologic evaluation. American Speech-Language-Hearing Association. ASHA Suppl 2:17–24

    Google Scholar 

  18. Wilson PH, Henry J, Bowen M et al (1991) Tinnitus reaction questionnaire: pyscometric properties of a measure of distress associated with tinnitus. J Speech Hear Res 34:197–201

    Article  CAS  Google Scholar 

  19. Eğilmez OK, Kalcıoğlu MT, Kökten N (2014) Questionnaire methods used in the psychosomatic evaluation of tinnitus. J Ear Nose Throat 24(5):303–310

    Article  Google Scholar 

  20. Ak E, Harputluoglu U, Oghan F et al (2004) Behçet’s disease and hearing loss. Auris Nasus Larynx 31:29–33

    Article  Google Scholar 

  21. Süslü AE, Polat M, Köybaşi S et al (2010) Inner ear involvement in Behçet's disease. Auris Nasus Larynx 37(3):286–290

    Article  Google Scholar 

  22. Choung YH, Cho MJ, Park K et al (2006) Audiovestibular disturbance in patients with Behcet’s disease. Laryngoscope 116:1987–1990

    Article  Google Scholar 

  23. Andreoli C, Savastano M (1989) Audiologic pathology in Behçet syndrome. Am J Otol 10:466–467

    PubMed  CAS  Google Scholar 

  24. Alajouanine T, Castaigne P, Lhermitte F et al (1961) The meningoencephalitis of Behcet’s disease. Presse Med 69:2579–2582

    PubMed  CAS  Google Scholar 

  25. Bakhshaee M, Ghasemi MM, Hatef MR et al (2007) Hearing loss in Behçet syndrome. Otolaryngol Head Neck Surg 137:439–442

    Article  Google Scholar 

  26. Aslan S, Serarslan G, Savas N et al (2010) Hearing loss in patients with Behçet’s disease: an audiological and transient evoked otoacoustic emission study. J Laryngol Otol 124:10–15

    Article  CAS  Google Scholar 

  27. Bayazit Y, Evereklioglu C, Ozer E et al (2004) Neurotological status in Behcet’s disease and its ophthalmological correlates. Postgrad Med J 80:724–728

    Article  CAS  Google Scholar 

  28. Yarıktaş M, Yıldırım M, Döner F et al (2004) Hearing loss in Behcet's disease. Medical journal of Suleyman Demirel University 11(1):18–20

    Google Scholar 

  29. Kemal O, Anadolu Y, Boyvat A et al (2013) Behcet disease as a cause of hearing loss: a prospective, placebo-controlled study of 29 patients. Ear Nose Throat 92(3):112–120

    Article  Google Scholar 

Download references

Funding

This study was not funded by any sources.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ahmet Karadağ.

Ethics declarations

Conflict of interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Karadağ, A., Karadağ, M., Bora, A. et al. Evaluation of hearing loss and tinnitus in Behcet’s disease. Eur Arch Otorhinolaryngol 276, 2691–2696 (2019). https://doi.org/10.1007/s00405-019-05506-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-019-05506-5

Keywords

Navigation