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The controversy in the management of the N0 neck for squamous cell carcinoma of the maxillary sinus

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European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Squamous cell carcinoma (SCC) of the maxillary sinus is a relatively rare disease. As the reported incidence of regional metastasis varies widely, controversy exists as to whether or not the N0 classified neck should be treated electively. In this review, the data from published series are analyzed to decide on a recommendation of elective treatment of the neck in maxillary SCC. The published series consist of heterogeneous populations of different subsites of the paranasal sinuses, different histological types, different staging and treatment modalities used and different ways of reporting the results. These factors do not allow for recommendations based on high levels of evidence. Given this fact, the relatively high incidence rate of regional metastasis at presentation or in follow-up in the untreated N0 neck, and the relatively low toxicity of elective neck irradiation, such irradiation in SCC of the maxillary sinus should be considered.

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Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    Robert P. Takes

  2. ENT Clinic, University of Udine, Udine, Italy

    Alfio Ferlito, Alessandra Rinaldo & Vanni Mondin

  3. Departments of Surgery and Otolaryngology-Head and Neck Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA

    Carl E. Silver

  4. Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma, OK, USA

    Jesus E. Medina

  5. Division of Otolaryngology-Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL, USA

    K. Thomas Robbins

  6. Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain

    Juan P. Rodrigo & Carlos Suárez

  7. Instituto Universitario de Oncología Del Principado de Asturias, Oviedo, Spain

    Juan P. Rodrigo & Carlos Suárez

  8. Department of Head and Neck Surgery, Head and Neck Oncology Program, St. Luc University Hospital and Cancer Center, Brussels, Belgium

    Marc Hamoir

  9. Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital, Berne, Switzerland

    Peter Zbären

  10. Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Ashok R. Shaha

  11. Department of Radiation Oncology, University of Florida, Gainesville, FL, USA

    William M. Mendenhall

  12. Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia

    Primož Strojan

Authors
  1. Robert P. Takes
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  2. Alfio Ferlito
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  3. Carl E. Silver
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  4. Alessandra Rinaldo
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  5. Jesus E. Medina
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  6. K. Thomas Robbins
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  7. Juan P. Rodrigo
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  8. Marc Hamoir
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  9. Carlos Suárez
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  10. Peter Zbären
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  11. Vanni Mondin
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  12. Ashok R. Shaha
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  13. William M. Mendenhall
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  14. Primož Strojan
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Corresponding author

Correspondence to Robert P. Takes.

Additional information

This paper was written by members and invitees of the International Head and Neck Scientific Group (www.IHNSG.com).

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Takes, R.P., Ferlito, A., Silver, C.E. et al. The controversy in the management of the N0 neck for squamous cell carcinoma of the maxillary sinus. Eur Arch Otorhinolaryngol 271, 899–904 (2014). https://doi.org/10.1007/s00405-013-2591-0

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  • DOI: https://doi.org/10.1007/s00405-013-2591-0

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