Abstract
Introduction
Most endometrial stromal sarcomas (ESS) develop recurrent disease at pelvis and lung. Recurrent ESS in the cecum causing intussusception is a rare but emergent phenomenon.
Case report
After initial surgical treatment in 1997, a 41-year-old female developed recurrent ESS in the cecum causing ileo-colic intussusception in 2008, which were operated with right hemicolectomy. The patient was then treated with progestin for 2 years to date. She has since been disease-free.
Conclusion
This case report emphasizes the importance of long-term follow-up and initial surgical treatment of ESS and suggests systemic hormonal therapy in case of recurrence.
References
Major FJ, Blessing JA, Silverberg SG et al (1993) Prognostic factors in early-stage uterine sarcoma. A Gynecologic Oncology Group study. Cancer 71:1702–1709
D’Angelo E, Prat J (2010) Uterine sarcomas: a review. Gynecol Oncol 116:131–139
Lax SF (2007) Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium. Pathology 39:46–54
Tavassoli F, Devilee P (2003) Pathology and genetics of tumours of the breast and female genital organs. In: World Health Organization classification of tumours. IARC Press, Lyon
Tavassoli FA, Norris HJ (1981) Mesenchymal tumours of the uterus. VII. A clinicopathological study of 60 endometrial stromal nodules. Histopathology 5:1–10
Sutton GP, Stehman FB, Michael H, Young PC, Ehrlich CE (1986) Estrogen and progesterone receptors in uterine sarcomas. Obstet Gynecol 68:709–714
Chu MC, Mor G, Lim C, Zheng W, Parkash V, Schwartz PE (2003) Low-grade endometrial stromal sarcoma: hormonal aspects. Gynecol Oncol 90:170–176
Boardman CH, Webb MJ, Jefferies JA (2000) Low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer. Gynecol Oncol 79:120–123
Huang BY, Warshauer DM (2003) Adult intussusception: diagnosis and clinical relevance. Radiol Clin North Am 41:1137–1151
Reich O, Regauer S (2007) Hormonal therapy of endometrial stromal sarcoma. Curr Opin Oncol 19:347–352
Bal A, Mohan H, Aulakh R, Huria A (2008) Endometrial stromal lesions: a morphological and immunohistochemical study of short series. Arch Gynecol Obstet 277:21–24
Aubry MC, Myers JL, Colby TV, Leslie KO, Tazelaar HD (2002) Endometrial stromal sarcoma metastatic to the lung: a detailed analysis of 16 patients. Am J Surg Pathol 26:440–449
Dahhan T, Fons G, Buist MR, Ten Kate FJ, van der Velden J (2009) The efficacy of hormonal treatment for residual or recurrent low-grade endometrial stromal sarcoma. A retrospective study. Eur J Obstet Gynecol Reprod Biol 144:80–84
Leath CA III, Huh WK, Hyde J Jr et al (2007) A multi-institutional review of outcomes of endometrial stromal sarcoma. Gynecol Oncol 105:630–634
Amant F, Coosemans A, Debiec-Rychter M, Timmerman D, Vergote I (2009) Clinical management of uterine sarcomas. Lancet Oncol 10:1188–1198
Kim WY, Lee JW, Choi CH et al (2008) Low-grade endometrial stromal sarcoma: a single center’s experience with 22 cases. Int J Gynecol Cancer 18:1084–1089
Thomas MB, Keeney GL, Podratz KC, Dowdy SC (2009) Endometrial stromal sarcoma: treatment and patterns of recurrence. Int J Gynecol Cancer 19:253–256
Amant F, Moerman P, Cadron I, Neven P, Berteloot P, Vergote I (2003) The diagnostic problem of endometrial stromal sarcoma: report on six cases. Gynecol Oncol 90:37–43
Li N, Wu LY, Zhang HT, An JS, Li XG, Ma SK (2008) Treatment options in stage I endometrial stromal sarcoma: a retrospective analysis of 53 cases. Gynecol Oncol 108:306–311
Conflict of interest statement
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Li, CH., Chang, WC. Recurrent endometrial stromal sarcoma in the cecum causing intussusception. Arch Gynecol Obstet 283, 899–901 (2011). https://doi.org/10.1007/s00404-010-1508-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00404-010-1508-z