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Oxidant/antioxidant status in premenstrual syndrome

  • General Gynecology
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Abstract

Purpose

To investigate oxidant/antioxidant status in premenstrual syndrome (PMS).

Methods

Study group (n = 20) consisted of PMS and control group (n = 21) consisted of normal menstruating women. The serum oxidant status was assessed by the lipid hydroperoxide (LHP), malondialdehyde (MDA) and protein carbonyl (PC); the antioxidant status was assessed by the total thiol (T-SH) and total antioxidant capacity (TAC).

Results

The study and control groups revealed no statistical difference, in terms of day 3 LHP, MDA, PC, T-SH and TAC levels. There were no significant differences between groups in terms of day 21 MDA, PC and T-SH levels. However, day 21 LHP levels were increased and TAC levels were decreased in the study group compared with the control group.

Conclusion

Increased oxidative stress and reduced antioxidant capacity may occur in PMS. It can be speculated that the imbalance of oxidant/antioxidant systems may be a cause or the consequence of the various stress symptoms in PMS.

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Conflict of interest statement

I certify that no actual or potential conflict of interest in relation to this article exists.

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Authors and Affiliations

  1. Department of Obstetric and Gynecology, University of Fatih, Hosdere Cad. No: 145, Yukari Ayranci, 06540, Ankara, Turkey

    Candan Iltemir Duvan, Nilgun Ozturk Turhan & Hasan Kafali

  2. Department of Biochemistry, University of Gazi, Ankara, Turkey

    Ahmet Cumaoglu

  3. Department of Pharmacology, University of Gazi, Ankara, Turkey

    Cimen Karasu

Authors
  1. Candan Iltemir Duvan
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  2. Ahmet Cumaoglu
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  3. Nilgun Ozturk Turhan
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  4. Cimen Karasu
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  5. Hasan Kafali
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Correspondence to Candan Iltemir Duvan.

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Duvan, C.I., Cumaoglu, A., Turhan, N.O. et al. Oxidant/antioxidant status in premenstrual syndrome. Arch Gynecol Obstet 283, 299–304 (2011). https://doi.org/10.1007/s00404-009-1347-y

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  • DOI: https://doi.org/10.1007/s00404-009-1347-y

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