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Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review

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Abstract

Introduction

Struma ovarii is a rare form of ovarian neoplasm and consists mainly of thyroid tissue. Ascites has been reported in approximately one-third of all the cases. However, the combination of struma ovarii and elevated CA-125 has rarely been reported.

Materials and methods

We described a case of benign struma ovarii, presenting with the clinical features of ovarian cancer: large complex pelvic mass, gross ascites and markedly elevated serum CA-125 levels. Surgical excision of the ovarian mass was followed by rapid resolution of the ascites and reduction of the serum CA-125 level.

Conclusion

Struma ovarii can mimic ovarian malignancy clinically, when presented with ascites and an elevated CA-125 level.

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Acknowledgments

The authors would like to thank Professor Annie Cheung for her support on pathological field.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Centro Hospitalar Conde de S. Januario, Macao, People’s Republic of China

    Mabel Po Mui

  2. Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, Hong Kong, People’s Republic of China

    Kar-fai Tam & Hextan Y. S. Ngan

  3. Department of Pathology, University of Hong Kong, Queen Mary Hospital, Hong Kong, People’s Republic of China

    Fiona K. Y. Tam

Authors
  1. Mabel Po Mui
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  2. Kar-fai Tam
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  3. Fiona K. Y. Tam
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  4. Hextan Y. S. Ngan
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Correspondence to Mabel Po Mui.

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Mui, M.P., Tam, Kf., Tam, F.K.Y. et al. Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review. Arch Gynecol Obstet 279, 753–757 (2009). https://doi.org/10.1007/s00404-008-0794-1

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  • DOI: https://doi.org/10.1007/s00404-008-0794-1

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