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Malignant melanoma arising in a burn scar

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Abstract

Secondary malignancies are rare but devastating complications of longstanding burn scars. Squamous cell carcinoma is the most common, followed by basal cell carcinoma and melanomas. There are fewer than 50 total reported cases of malignant melanomas arising in burn scars. We report a case of malignant melanoma arising within a longstanding burn scar confirmed by histology, FISH, and PRAME staining to further characterize melanomas arising in burn scars and to illustrate the diagnostic challenges they present.

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No datasets were generated or analysed during the current study.

Abbreviations

BCC:

Basal cell carcinoma

SCC:

Squamous cell carcinoma

PRAME:

Preferentially expressed antigen in melanoma

FISH:

Fluorescence in situ hybridization

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Authors and Affiliations

  1. University of Maryland School of Medicine, Baltimore Maryland, USA

    Emily Ma

  2. Department of Dermatology, University of Maryland Medical Center, Baltimore, MD, USA

    Shealinna Ge

  3. Joint Pathology Center, 606 Stephen Sitter Avenue, Silver Spring, MD, 20910, USA

    Walter L. Rush & Jill Allbritton

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  1. Emily Ma
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  2. Shealinna Ge
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  3. Walter L. Rush
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  4. Jill Allbritton
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EM wrote the main manuscript text and prepared the table. SG prepared the figures. All authors edited and reviewed the manuscript.

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Correspondence to Jill Allbritton.

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Ma, E., Ge, S., Rush, W.L. et al. Malignant melanoma arising in a burn scar. Arch Dermatol Res 316, 146 (2024). https://doi.org/10.1007/s00403-024-02861-0

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