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Compliance status and influencing factors of anticoagulation therapy in outpatient undergoing major orthopedic surgery

  • Orthopaedic Surgery
  • Published:
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Abstract

Purpose

This study was designed to investigate influencing factors of out-of-hospital anticoagulation therapy compliance among patients undergoing major orthopaedic surgeries.

Methods

A cross-sectional, descriptive study was conducted from July 2022 to February 2023 among outpatients who underwent major orthopedic surgery in our hospital. Patients (n = 200) were surveyed using the General Information Questionnaire, the General Self-Efficacy Scale, the Specificity of Medication-Taking Beliefs Scale, and the Morisky Medication Adherence Scale. Factors that influenced patient compliance were also determined using univariate and multivariate regression analyses.

Results

One hundred eighty-three valid questionnaires were returned, the compliance with outpatient anticoagulation therapy among patients undergoing major orthopaedic surgeries was good in 56.3% (103/183) of all cases and poor in 43.7% (80/183). Multivariate logistic regression analysis showed that medication duration, adverse effects, self-efficacy and medication beliefs influenced adherence to out-of-hospital anticoagulation therapy in patients undergoing major orthopedic surgery (P < 0.05).

Conclusions

Poor compliance with out-of-hospital anticoagulation therapy in patients undergoing major orthopedic surgery is mainly associated with a long course of medication, adverse reactions, low self-efficacy and low medication beliefs. Healthcare staff should strengthen post-discharge anticoagulation management based on relevant influencing factors to enhance patient compliance.

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Data availability

Data are available from the corresponding author upon reasonable request.

Code availability

Not applicable.

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Acknowledgements

We wish to thank all the patients who participated in this study and the administrators in the hospitals who made the study possible.

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

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Author notes

  1. Wenqi Hu

    Present address: Department of Surgical Clinic, The First Affiliated Hospital of China Medical University, Liaoning, 110001, China

Authors and Affiliations

  1. School of Nursing, China Medical University, Liaoning, 110122, China

    Wenqi Hu

  2. Department of Surgical Clinic, The First Affiliated Hospital of China Medical University, Liaoning, 110001, China

    Mao Ye

Authors
  1. Wenqi Hu
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  2. Mao Ye
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by WH and MY. WH wrote the paper. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Mao Ye.

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Conflict of interest

The authors declare no competing interests.

Ethical approval

The Medical Ethics Committee of the First Affiliated Hospital of China Medical University approved this study (No. 2023135).

Informed consent

Written informed consent was obtained from all study participants before participation.

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Hu, W., Ye, M. Compliance status and influencing factors of anticoagulation therapy in outpatient undergoing major orthopedic surgery. Arch Orthop Trauma Surg 144, 583–589 (2024). https://doi.org/10.1007/s00402-023-05106-3

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  • DOI: https://doi.org/10.1007/s00402-023-05106-3

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