Abstract
A 36-year-old Japanese male, who 7 years previously had been diagnosed as having an ependymoma in the left parietal region, had received surgery, chemotherapy and radiotherapy. He later developed a rapid growth of multiple skin lesions on his back and extremities, which coincided with a regrowth of the tumor. Postmortem examination revealed that the ependymoma showed anaplastic transformation and necrosis; however, no malignancy was observed in the extracranial organs. The skin lesions were histologically diagnosed as seborrheic keratoses. We have, therefore, diagnosed the patient as having Leser-Trélat sign associated with anaplastic ependymoma.
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Received: 5 May 1996 / Revised, accepted: 15 July 1996
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Hamada, Y., Iwaki, T., Muratani, H. et al. Leser-Trélat sign with anaplastic ependymoma – an autopsy case. Acta Neuropathol 93, 97–100 (1996). https://doi.org/10.1007/s004010050588
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DOI: https://doi.org/10.1007/s004010050588