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Probing the internal environment of PVP networks generated by irradiation with different sources

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Abstract

Poly(N-vinyl-2-pyrrolidone) (PVP) hydrogels have been synthesised from the aqueous solutions of the same linear polymer by two different radiation sources: electron beams and UV rays. The present investigation couples conventional hydrogel characterisation techniques with the study of the partition equilibria, fluorescence behaviour and release of two different molecular probes, 1-anilino-8-naphthalene sulphonate (ANS) and Thioflavin T (ThT). The two probes have comparable molecular weight and different structural and optical properties. The ‘chemical’ networks produced upon irradiation in different experimental conditions presented quite distinctive mechanical spectra, yielded to different porous solids upon freeze-drying and showed specific rehydration ratios when ‘equilibrated’ in water. More interestingly, they offered ‘hydrophobic pockets’ to host the ANS molecules in a way that the probe is completely occluded from water, making it fluoresce. Conversely, the generated PVP networks did not show any specific affinity towards the hydrophilic ThT that was only barely untaken.

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Author notes

  1. Vito Foderà

    Present address: Sector of Biological and Soft Systems, Department of Physics, Cavendish Laboratory, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0HE, UK

Authors and Affiliations

  1. Dipartimento di Ingegneria Chimica dei Processi e dei Materiali, Università di Palermo, Viale delle Scienze Ed. 6, 90100, Palermo, Italy

    Mariaelena Ricca, Giuseppe Spadaro & Clelia Dispenza

  2. Dipartimento di Scienze Fisiche ed Astronomiche, Università di Palermo, Via Archirafi 36, 90123, Palermo, Italy

    Vito Foderà & Maurizio Leone

  3. CNR—Istituto di Biofisica, U.O. Via U. La Malfa 153, 90146, Palermo, Italy

    Vito Foderà, Daniela Giacomazza & Maurizio Leone

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  1. Mariaelena Ricca
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Correspondence to Clelia Dispenza.

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Ricca, M., Foderà, V., Giacomazza, D. et al. Probing the internal environment of PVP networks generated by irradiation with different sources. Colloid Polym Sci 288, 969–980 (2010). https://doi.org/10.1007/s00396-010-2217-7

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  • DOI: https://doi.org/10.1007/s00396-010-2217-7

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